Test Price
2,800 AED✅ Home Collection Available
GATA6 Gene – Tetralogy of Fallot Next‑Generation Sequencing (NGS) Genetic Test in UAE | AED 2800 | DNA Labs UAE
Executive Summary & Core Metrics
The GATA6 gene NGS test delivers 99.9% diagnostic sensitivity for detecting pathogenic variants associated with Tetralogy of Fallot and related congenital heart defects, performed under ISO‑accredited protocols (Cert: INT/EGQ/2509DA/3139) within the DHA‑licensed facility of DNA Labs UAE.
- Accuracy: 99.9% analytical sensitivity covering coding exons ± 20 bp splice junctions via Illumina NGS platform.
- Collection Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection – Available daily from 8 AM to 11 PM across all seven emirates.
- Post‑Test Support: Complimentary tele‑counselling session with a Consultant Medical Genetics specialist to interpret results and guide family cascade screening.
- Insurance Verification: Direct billing confirmation via WhatsApp +971 54 548 8731 (major UAE insurers accepted).
Test Overview & Methodology
This molecular assay employs next‑generation sequencing to interrogate the entire coding region and canonical splice sites of the GATA6 gene. Pathogenic variants in GATA6 are linked to Tetralogy of Fallot, truncus arteriosus, and other conotruncal heart defects, making this test essential for reproductive risk assessment, surgical prognostication, and cascade screening of at‑risk relatives.
| Feature | Our Test – GATA6 NGS (DNA Labs UAE) | Closest Alternative – Single‑Gene Sanger Sequencing |
|---|---|---|
| Precision | 99.9% analytical sensitivity; full coding exon ± 20 bp splice junction coverage | ~99% sensitivity for targeted regions; limited flanking intronic coverage |
| Method | Illumina‑based NGS with orthogonal bioinformatics confirmation | Capillary electrophoresis Sanger sequencing |
| Turnaround Time | 3–4 Weeks (including cold‑chain logistics) | 4–8 Weeks (frequent shipment delays) |
| Compliance | DHA‑licensed facility (License 1143), ISO 9001:2015, UAE PDPL compliant | Variable overseas certification; no local DHA oversight |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics specialist, I emphasise that a genetic finding constitutes one component of a comprehensive diagnostic evaluation. Echocardiographic findings, family pedigree analysis, and clinical history must be integrated before any surgical or reproductive decision is made. Knowledge of GATA6 variant status enables tailored surveillance, but ongoing follow‑up with a paediatric cardiologist or adult congenital heart specialist remains essential.”
– Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Medication Advisory
Do not discontinue any prescribed cardiac or anticoagulant medication before discussing the test results with your treating physician. Genetic information augments but does not replace real‑time clinical assessment.
Patient Safety – Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Individuals experiencing acute cardiac decompensation, unstable angina, or recent myocardial infarction should postpone elective genetic testing until medically stable.
- Exclusion Criteria: Patients with severe anxiety or uncontrolled psychiatric conditions must be assessed by a genetic counsellor before testing to avoid psychological distress.
- ER Red Flags: New‑onset cyanosis, hyper‑cyanotic spells (Tet spells), syncope, or severe dyspnoea require immediate emergency care – genetic test results do not address acute life‑threatening events.
Patient FAQ & Clinical Guidance
1. How accurate is the GATA6 NGS test for Tetralogy of Fallot?
With 99.9% analytical sensitivity and complete coding‑region coverage via next‑generation sequencing, this test reliably detects pathogenic and likely pathogenic variants in the GATA6 gene.
2. Can a parent pass the GATA6 mutation to their child, and how is the risk calculated?
Inheritance is autosomal dominant; a single affected parent carries a 50% risk per pregnancy, which our genetic counselling session explains in detail before and after testing.
3. Is home sample collection available across all UAE emirates, and how should I prepare?
Yes, VIP Mobile Phlebotomy is available daily from 8 AM to 11 PM across all seven emirates. Avoid eating for three hours prior to collection and provide the patient’s latest echocardiogram report during the visit.
4. What are the pre‑test requirements for this genetic test?
A detailed clinical history and a pre‑test genetic counselling session are required to construct a full pedigree chart of family members affected with GATA6‑related heart defects. The sample accepted is whole blood (EDTA), extracted DNA, or one drop of blood on an FTA card.
5. Does health insurance in the UAE cover the cost of the GATA6 genetic test?
Coverage is available under most major UAE insurance plans. Verify your specific policy by contacting us via WhatsApp at +971 54 548 8731 for a direct billing confirmation.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates in full compliance with UAE federal data protection and health information governance frameworks. All genetic data is processed under:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – governing the collection, storage, and transfer of personal genomic data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – regulating electronic health records and tele‑counselling platforms.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – establishing the standard of care for genetic testing, patient consent, and clinical safety.
All test results are transmitted via encrypted channels, and identifiable genetic information is never shared with third parties without explicit patient consent.
Clinical & Logistical Metadata
| Test Name | GATA6 Gene – Tetralogy of Fallot NGS Genetic Test |
| Price (AED) | 2800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card Blood Spot – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily 8 AM–11 PM |
| Methodology Used | Next‑Generation Sequencing (NGS) – Illumina platform with orthogonal bioinformatics confirmation |
| ICD-10-CM Code | Q21.3 (Tetralogy of Fallot) |
| LOINC Code | 81320-5 (GATA6 gene targeted mutation analysis) |
| DHA Facility License & Laboratory Address | DHA License Number: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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