Test Price
2,800 AED✅ Home Collection Available
MYH6 Gene Dilated Cardiomyopathy Type 1EE Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by Consultant Medical Genetics Lina Osama Zaki Quteineh (DHA ID: 9294403).
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The MYH6 NGS test detects pathogenic variants in the cardiac beta-myosin heavy chain gene, providing a definitive molecular diagnosis for dilated cardiomyopathy type 1EE. This test is essential for personalised cardiac care, family cascade screening, and informed reproductive decisions in the UAE.
| Feature | Our Test (NGS) | Closest Alternative (Single-Gene Sanger) |
|---|---|---|
| Methodology | Next Generation Sequencing – full MYH6 gene coverage | Sanger sequencing – limited to known hot-spots |
| Diagnostic Sensitivity | >99.9% for single-nucleotide variants and indels | ~85–90%, may miss deep intronic/regulatory variants |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks (often requires reflex to NGS) |
| Sample Requirement | Whole Blood, Extracted DNA, or one drop on FTA Card | Typically 3–5 mL whole blood only |
Physician Insight & Safety Protocols
"A positive genetic finding in MYH6 is not a standalone diagnosis; it must be correlated with echocardiographic and clinical data. I advise every patient to view this result as a powerful family risk tool, not an inevitability, and to remain under multiparametric cardiac surveillance."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication & Clinical Advisory
⚠️ Important Medication Notice
Do not discontinue prescribed cardiac medication such as beta-blockers or ACE inhibitors without consulting your treating physician. Abrupt cessation can lead to acute clinical decompensation.
Safety Exclusion Criteria & Emergency Red Flags
Absolute Contraindications & Precautions
- Testing is not recommended for minors without legal guardian consent as per Federal Decree-Law No. 4 of 2016 on Medical Liability.
- No absolute medical contraindications for standard blood draw; however, sampling may be deferred in cases of acute heart failure decompensation.
- Seek emergency care (998) immediately if you experience: crushing chest pain, severe shortness of breath, syncope, or palpitations with dizziness.
Patient FAQ & Clinical Guidance
1. What is the MYH6 gene and how does it cause dilated cardiomyopathy?
The MYH6 gene encodes the cardiac beta-myosin heavy chain, a critical motor protein for heart muscle contraction. Pathogenic mutations disrupt the sarcomere structure, leading to progressive ventricular dilation and systolic dysfunction.
2. Who should consider this genetic test?
Individuals with a family history of dilated cardiomyopathy, idiopathic heart failure, or sudden cardiac death should consider this test. It is also strongly indicated for patients presenting with early-onset cardiomyopathy without a clear etiology.
3. How accurate is this NGS test and what does a positive result mean?
With 99.9% sensitivity for single-nucleotide variants and indels, a positive result confirms a pathogenic mutation linked to dilated cardiomyopathy. This finding directs family cascade screening and informs clinical management and surveillance strategies.
UAE Regulatory & Data Privacy Adherence
Your Data Protection & Compliance Framework
- Data Privacy: Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL). Your genetic data is encrypted, anonymized, and processed within secure UAE-based servers.
- Health Information Governance: Adheres to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, ensuring strict confidentiality and integrity of electronic health records.
- Medical Liability: All clinical procedures follow Federal Decree-Law No. 4 of 2016 on Medical Liability, guaranteeing informed consent and professional accountability.
Clinical & Logistical Metadata
| Test Name | MYH6 Gene Dilated Cardiomyopathy Type 1EE Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 - 4 Weeks |
| Sample Type / Matrix | Whole Blood (3-5 mL), Extracted DNA, or FTA Card |
| Methodology Used | Next Generation Sequencing (NGS) – Full MYH6 gene coverage |
| ICD-10-CM Code | I42.0 |
| LOINC Code | 90569-1 |
| DHA Facility License & Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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