Test Price
2,800 AEDโ Home Collection Available
LMNA Gene Cardiomyopathy (Dilated Type 1A) Genetic Test in UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic post-test clinical result interpretation with DHA-licensed consultants.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
- Price: 2,800 AED inclusive of NGS sequencing, bioinformatic analysis, and genetic counselling.
Test Overview & Methodology
The LMNA Gene Cardiomyopathy (Dilated Type 1A) Genetic Test employs next-generation sequencing (NGS) to detect pathogenic variants in the LMNA gene responsible for autosomal dominant dilated cardiomyopathy with high arrhythmic risk. This assay serves as the definitive molecular diagnostic for patients with familial cardiomyopathy, supporting precise risk stratification and cascade screening. Our laboratory integrates full gene NGS with MLPA for structural variant detection, achieving 99.9% analytical sensitivity across all coding regions and splice sites.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | NGS with 99.9% analytical sensitivity | Sanger sequencing of selected exons (~90%) |
| Method | Full gene NGS + MLPA for structural variants | Single-gene PCR-based panel |
| Speed | 3โ4 Weeks | 6โ8 Weeks (external referral) |
Physician Insight & Safety Protocols
โAs a Consultant Medical Genetics specialist, I consider LMNA genetic testing essential when clinical signs or family history suggest laminopathy; negative imaging does not exclude a lethal arrhythmia risk. I strongly advise that all results be correlated with a comprehensive cardiac evaluation, including ECG and echocardiogram, and shared with a clinical geneticist for cascade screening of first-degree relatives.โ โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Important Medication Advisory
Do not discontinue prescribed medication without consulting your doctor. Genetic test results do not overrule current cardioprotective therapy, and sudden withdrawal of beta-blockers or ACE inhibitors may precipitate acute decompensation. Continue all prescribed treatments until your physician advises otherwise based on the integrated clinical and genetic findings.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Active febrile illness or haemodynamic instability at time of home venipuncture.
- Exclusion: Inability to provide informed consent or legal guardian approval (mandatory for minors per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Emergency Red Flags: If you experience syncope, sustained palpitations, or new-onset chest pain during the testing period, call 998 or proceed to your nearest emergency department immediately.
Patient FAQ & Clinical Guidance
1. What does the LMNA NGS reveal about my heart muscle disease?
A comprehensive LMNA gene analysis identifies pathogenic mutations that cause dilated cardiomyopathy type 1A, enabling personalised arrhythmia risk stratification and family screening. The test distinguishes laminopathy from other genetic cardiomyopathies, guiding the use of implantable cardioverter-defibrillator (ICD) therapy in high-risk individuals.
2. How is the sample collected and what happens during home collection?
A certified phlebotomist arrives with temperature-controlled cold-chain transport and collects one blood tube (peripheral whole blood). The VIP Mobile Phlebotomy service operates daily from 8 AM to 11 PM, with all samples processed within the ISO 9001:2015 accredited laboratory in Dubai Healthcare City.
3. When will I receive my results and who will explain them?
The report is delivered in 3 to 4 weeks, accompanied by a telephonic consultation with a genetic counsellor and cardiologist to interpret the findings. Results include variant classification per ACMG guidelines, clinical recommendations, and cascade screening advice for at-risk family members.
4. Is genetic counselling included in the test price?
Yes, pre-test and post-test genetic counselling is included in the 2,800 AED fee. A DHA-licensed Consultant Medical Genetics specialist reviews your family history, explains the implications of potential results, and provides a written post-test summary for your referring physician.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Legal Compliance
This service adheres strictly to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is stored within UAE borders under ISO 9001:2015 certified processes (Cert: INT/EGQ/2509DA/3139). Clinical testing safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | LMNA Gene Cardiomyopathy (Dilated Type 1A) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (3โ5 mL in EDTA tube) or DNA FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) + MLPA for Structural Variants |
| ICD-10-CM Code | I42.0 (Dilated cardiomyopathy) |
| LOINC Code | 82248-7 (LMNA gene mutation analysis in Blood or Tissue by NGS) |
| DHA Facility License & Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians