Test Price
2,800 AED✅ Home Collection Available
KCNE2 Gene Atrial Fibrillation Type 4 Genetic Test in UAE | 2800 AED | DHA Licensed Lab
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation provided by specialist team.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This Next-Generation Sequencing (NGS) test analyzes the entire KCNE2 gene to detect pathogenic variants responsible for hereditary atrial fibrillation type 4 (ATFB4), enabling accurate cardiovascular risk stratification and personalized prevention. The assay uses Illumina NovaSeq X Plus technology to achieve comprehensive gene coverage, identifying single nucleotide variants (SNVs) and small insertions/deletions with high analytical sensitivity.
| Feature | Our Test (KCNE2 NGS) | Closest Alternative (Standard Sanger Sequencing) |
|---|---|---|
| Methodology | Illumina NovaSeq X Plus – comprehensive gene analysis | Single-gene Sanger sequencing |
| Analytical Sensitivity | >99.9% for all variant types (SNVs, indels) | ~98% (misses deep intronic/novel variants) |
| Turnaround Time | 3–4 Weeks | 1–2 Weeks |
| Clinical Utility | Full gene coverage – prognostic, familial screening, targeted therapy | Limited to previously known mutations only |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics specialist, I recognise that a family history of atrial fibrillation raises important questions about inherited risk. This KCNE2 gene test offers precise molecular insight, but it must always be interpreted alongside a thorough clinical evaluation, pedigree analysis, and ECG findings. Results should guide shared decision-making with your cardiologist and genetic counsellor. Continue all prescribed therapies and attend regular follow-up visits."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory – Medication & Pre-Test Guidance
Pre-Test Preparation
- A genetic counselling session is mandatory to document a three-generation family pedigree and discuss implications.
- Sample: Blood (EDTA whole blood), extracted DNA, or one drop blood on FTA card. Fasting not required.
- Critical: If you are taking anticoagulants (blood thinners), do not stop them without explicit instruction from your cardiologist. Continue all prescribed medications unless your doctor advises otherwise.
Safety Exclusion Criteria & Emergency Red Flags
Exclusion Criteria (Do Not Test If)
- Active febrile illness (temperature >38.5°C)
- Recent major surgery or blood transfusion (<2 weeks)
- Severe anemia (Hb <7 g/dL) or thrombocytopenia (platelets <50×10⁹/L)
- Inability to provide blood sample due to poor venous access without clinical clearance
Emergency Red Flags – Call 998 Immediately
- Syncope (fainting) or near-fainting with palpitations
- Sudden chest pain, pressure, or shortness of breath at rest
- Rapid, irregular heartbeat accompanied by dizziness
- Signs of stroke: facial droop, arm weakness, speech difficulty
Patient FAQ & Clinical Guidance
1. What is the KCNE2 atrial fibrillation type 4 genetic test?
This genetic test detects KCNE2 mutations causing familial atrial fibrillation type 4, supporting risk management. The assay uses next-generation sequencing to read the entire KCNE2 gene, identifying both previously reported and novel variants. Results help cardiologists and genetic counsellors assess your inherited risk, guide surveillance (e.g., ECG monitoring, echocardiography), and inform family screening. Turnaround time is 3–4 weeks.
2. Who should consider this test?
Individuals with a strong family history of early-onset atrial fibrillation or unexplained sudden cardiac events should consider this test. It is particularly relevant for athletes, individuals with lone atrial fibrillation before age 60, and families with multiple affected members. A cardiology or clinical genetics consultation is recommended before testing to ensure appropriate context.
3. How does the home collection service work and what does the price include?
The 2800 AED package includes a cold-chain home blood draw, full NGS analysis, and a post-test clinical discussion. A trained phlebotomist arrives at your location between 8 AM and 11 PM, collects a small blood sample using a pain-minimizing technique, and transports it in a temperature-controlled chain to our ISO-certified laboratory. The price covers the genetic counselling session, sequencing, bioinformatics interpretation, and a comprehensive written report. Insurance pre-approval can be checked instantly via WhatsApp.
UAE Regulatory & Data Privacy Adherence
All genetic testing services at DNA Labs UAE are performed under the regulatory oversight of the Dubai Health Authority (DHA Facility License No. 1143). We comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Genetic data is processed with the highest privacy standards and stored in secure, access-controlled systems.
ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) | Contact: +971 54 548 8731 | WhatsApp: +971545488731
Clinical & Logistical Metadata
| Test Name | KCNE2 Gene Atrial Fibrillation Type 4 Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card Blood Spot |
| Methodology Used | Next-Generation Sequencing (Illumina NovaSeq X Plus) |
| ICD-10-CM Code | I48.91 |
| LOINC Code | 55233-1 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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