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Test Price

2,800 AED

✅ Home Collection Available

TNNT2 Gene Cardiomyopathy, Dilated Type 1D Genetic Test in UAE | 2,800 AED

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO-accredited whole-gene next-generation sequencing with Sanger confirmation.
  • Premium Logistics: VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM within Dubai.
  • Clinical Guidance: Post-test telephonic consultation for results interpretation in coordination with a consultant medical geneticist.
  • Insurance Support: Direct billing verification available via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

This advanced genetic test utilizes whole-gene next-generation sequencing (NGS) to analyze the TNNT2 gene for pathogenic variants causative of dilated cardiomyopathy type 1D. The assay delivers 99.9% diagnostic sensitivity through ISO-accredited laboratory processing, with all clinically significant variants verified by Sanger sequencing. Results enable precise diagnosis, prognostic stratification, and cascade screening for at-risk family members.

FeatureOur TNNT2 NGS TestStandard Targeted Panel
MethodologyWhole‑gene Next‑Generation Sequencing (NGS) + Sanger verificationTargeted mutation analysis, limited coverage
Diagnostic Sensitivity99.9%~95%
Turnaround Time3–4 Weeks6–8 Weeks
Sample TypesWhole Blood, Extracted DNA, FTA CardWhole Blood only
Price (AED)2,8003,500 – 4,200

Physician Insight & Safety Protocols

“The TNNT2 genetic test serves as a critical tool for confirming a genetic etiology in suspected dilated cardiomyopathy, yet its full clinical value depends on integration with echocardiographic data, electrocardiogram findings, and a three-generation family pedigree. A pathogenic variant indicates hereditary predisposition, but the age of onset and phenotypic expression remain variable. All results must be reviewed in a multidisciplinary setting involving a cardiologist and a certified genetic counselor before any therapeutic decisions are made.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory Notice

⚠️ Medication and Clinical Supervision

Do not discontinue, alter, or initiate any cardiac medication, including beta-blockers, ACE inhibitors, or anticoagulants, solely based on genetic test results. Treatment adjustments must be directed by your managing cardiologist following a complete clinical assessment. This genetic report is intended to complement, not replace, standard cardiac care protocols.

Exclusion Criteria & Emergency Red Flags

  • Exclusion Criteria: Testing is contraindicated for minors unaccompanied by a parent or legal guardian providing written informed consent, individuals unable to comprehend or sign the informed consent document, and patients currently experiencing an acute psychiatric crisis requiring emergency intervention.
  • Emergency Red Flags: Sudden onset of crushing chest pain, new or worsening palpitations, unexplained fainting (syncope), or severe shortness of breath demand immediate emergency medical evaluation at the nearest hospital. This genetic test does not substitute for acute clinical assessment or emergency cardiac care.

Patient FAQ & Clinical Guidance

1. What is the TNNT2 gene dilated cardiomyopathy test, and who should consider it?

The TNNT2 genetic test screens for mutations in the TNNT2 gene linked to dilated cardiomyopathy type 1D, recommended for individuals with family history, unexplained heart failure, or abnormal cardiac screening results. It is a definitive diagnostic tool used by cardiologists and geneticists to clarify etiology and guide management.

2. How accurate and reliable is this genetic test, and what does the process involve?

With 99.9% analytical sensitivity and Sanger confirmation, the test uses a blood or DNA sample, processed in an ISO-certified lab, delivering results in 3–4 weeks. The entire workflow is validated against current genomic databases, ensuring reproducible variant classification according to ACMG guidelines.

3. What do positive, negative, or uncertain results mean for my health and my family?

A positive result confirms a pathogenic TNNT2 variant, enabling targeted surveillance and family cascade testing; negative results reduce risk but do not eliminate other genetic or environmental causes. Variants of uncertain significance are re‑evaluated regularly and interpreted by a multidisciplinary team including your cardiologist and genetic counselor.

UAE Regulatory & Data Privacy Adherence

Data Protection & Health Information Governance

All patient genetic data and clinical records are processed and stored in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. These frameworks mandate strict encryption, access controls, and data minimization for all health information handled within UAE jurisdiction.

Clinical Safety & Patient Consent: All genetic testing procedures, sample collection protocols, and informed consent processes adhere to the standards outlined in Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring patient safety and professional accountability at every stage of the diagnostic pathway.

Clinical & Logistical Metadata

Test NameTNNT2 Gene Cardiomyopathy, Dilated Type 1D Genetic Test
Price (AED)2,800
Turnaround Time3–4 Weeks
Sample Type / MatrixWhole Blood (EDTA), Extracted DNA, FTA Card
Methodology UsedWhole-Gene Next-Generation Sequencing (NGS) with Sanger Confirmation
ICD-10-CM CodeI42.0 (Dilated cardiomyopathy)
LOINC Code81326-5 (Cardiomyopathy dilated type 1D gene TNNT2 full sequencing)
DHA Facility License & AddressLicense 1143 · Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE · DNA Labs UAE

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