Test Price
4,800 AED✅ Home Collection Available
Lung Cancer Mutation Panel 5 (EGFR, KRAS, BRAF, ALK1, ROS1) in UAE | 4800 AED | 2026 DHA Guidelines
تحليل لوحة طفرات سرطان الرئة 5 (EGFR, KRAS, BRAF, ALK1, ROS1) في الإمارات | 4800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – رؤية طبية موثوقة
ملخص تنفيذي: يوفر هذا التحليل الجزيئي الشامل تقييمًا دقيقًا لخمس طفرات جينية أساسية في سرطان الرئة غير صغير الخلايا، مما يتيح توجيه العلاج الموجه والتنبؤ بالاستجابة العلاجية وفق أعلى معايير الجودة العالمية.
- ✅ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO‑accredited dual technology processing — every result verified by two independent methods.
- ✅ Premium Logistics: Paid hospital‑grade home collection with ISO‑certified cold‑chain transportation and VIP mobile phlebotomy, available 8 AM to 11 PM daily.
- ✅ Clinical Guidance: Complimentary telephonic post‑test clinical guidance for result interpretation with our DHA‑licensed molecular oncologists.
- ✅ Insurance: Direct billing verification via WhatsApp at +971 54 548 8731 — most major UAE insurers accepted.
Overview – نظرة عامة
The Lung Cancer Mutation Panel 5 is a targeted molecular assay that simultaneously detects clinically actionable variants in EGFR, KRAS, BRAF, ALK1, and ROS1 from formalin‑fixed paraffin‑embedded (FFPE) or fresh tumor tissue. يوفر هذا الفحص الشامل معلومات حيوية لتوجيه العلاج المناعي والموجه بدقة، مما يساهم في تحقيق نتائج علاجية فائقة للمرضى المصابين بسرطان الرئة غير صغير الخلايا.
| Feature | Our Panel (يو ال سي إل) | Closest Alternative |
|---|---|---|
| Methodology | FISH (ALK1, ROS1) + Sanger Sequencing (EGFR, KRAS, BRAF) — dual orthogonal validation | Single‑gene PCR or next‑generation sequencing panel (often without simultaneous FISH) |
| Precision / Sensitivity | >99% analytical sensitivity for targeted mutations | Variable; NGS may miss certain structural rearrangements without confirmatory FISH |
| Turnaround Time | 5–7 working days | 7–14 days (NGS with reflex FISH) |
| Regulatory Compliance | ISO 9001:2015, DHA/MOHAP standardised report, complies with UAE PDPL | May lack local accreditation |
| Price (AED) | 4800 | Often higher for multi‑gene NGS (excluding home collection) |
Physician Insight & Safety Protocol – رؤية الطبيب وبروتوكول السلامة
“Every mutation profile is unique — I always correlate these results with your full clinical picture, imaging, and treatment history. No single biomarker decision should be made in isolation. I encourage you to discuss your report in a dedicated consultation where we translate these findings into a personalised care plan.”
— Dr. Prabhakar Reddy, DHA 61713011, Consultant Molecular Pathologist.
⚠️ Medication Warning
Do not discontinue prescribed medication without consulting your doctor.
If you are on targeted therapy (e.g., EGFR tyrosine kinase inhibitors), altering the dose can cause serious side effects or disease progression. Always coordinate with your oncology team.
Patient Safety Exclusion Criteria & ER Red Flags
- Exclusion: This test requires an adequate tumor tissue sample. Insufficient or necrotic specimens cannot be processed. Home collection is not performed on critically ill patients or those under active emergency care.
- Pregnancy & Surgery: Not suitable for cases of active pregnancy, planned surgery within 7 days, or patients travelling abroad without prior clinical clearance.
- Emergency Signs — seek immediate hospital care: New onset severe chest pain, sudden shortness of breath, coughing up bright red blood (hemoptysis), high fever unresponsive to antipyretics, or confusion.
- Minors: Genetic testing on minors requires explicit parental consent and adherence to the UAE Child Protection (CDS) Law 2026.
Pre‑Test Requirement: A valid physician’s prescription is mandatory. This test is contraindicated in cases of active surgery, pregnancy, or for individuals planning international travel without prior medical consultation.
Patient FAQ & Clinical Guidance – أسئلة المرضى الشائعة
1. What is the Lung Cancer Mutation Panel 5 and how does it guide targeted therapy?
This molecular test identifies actionable EGFR, KRAS, BRAF, ALK1, and ROS1 gene mutations in tumor tissue, enabling precise targeted therapy selection for non‑small cell lung cancer patients. These genes control cell growth; specific alterations predict response to tyrosine kinase inhibitors or ALK/ROS1 inhibitors. Detecting a sensitising EGFR mutation (exon 19 deletion or L858R) or an ALK1/ROS1 rearrangement can make you eligible for first‑line targeted therapy that may significantly improve outcomes.
2. How is the test performed and what preparation is needed?
A small amount of previously collected tumor tissue (FFPE block or slides) is used; no fasting or special preparation is required from you. Our team coordinates with your pathology lab to obtain the archival block or, if a fresh biopsy is needed, guides you through the hospital process. The sample undergoes DNA extraction, Sanger sequencing for point mutations, and FISH for gene rearrangements under strict quality controls.
3. ما هي أهمية تحليل طفرات سرطان الرئة في الإمارات وكيف يتم تفسير النتائج؟
يكشف هذا التحليل الجزيئي الطفرات الجينية في جينات EGFR وKRAS وBRAF وALK1 وROS1 بأنسجة الورم، مما يساعد في توجيه العلاج المناعي والموجه بدقة عالية للمرضى المصابين بسرطان الرئة غير صغير الخلايا. عند استلام التقرير، يقوم طبيب الأورام المعتمد من هيئة الصحة بدبي بتفسير النتائج جنبًا إلى جنب مع التاريخ المرضي الكامل والتصوير الطبي، لتحديد الأدوية المستهدفة الأنسب مثل مثبطات التايروسين كاينيز أو مثبطات ALK/ROS1، مع ضمان الخصوصية الكاملة وفقًا لقانون حماية البيانات الشخصية الإماراتي.
This is performed under ISO 9001:2015 certification (INT/EGQ/2509DA/3139) and fully complies with Federal Decree‑Law No. 41 of 2024 (Art. 87) on medical safety, the UAE PDPL for data privacy, and the CDS Law 2026 for minor protection. DHA facility license: 9834453.
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