Test Price
1,500 AED✅ Home Collection Available
Voltage-Gated Potassium Channel (VGKC) Antibody Serum Test in UAE | 1500 AED | DHA Licensed
Executive Summary & Core Metrics
99.9% Diagnostic Sensitivity – ISO 9001:2015 accredited processing using cell-based assay and immunofluorescence for direct LGI1 and CASPR2 detection.
Premium Logistics – VIP mobile phlebotomy with temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM.
Post-Test Clinical Guidance – Telephonic interpretation of results by a DHA-licensed general practitioner with neurology referral pathways.
Insurance & Billing – Direct verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The VGKC antibody serum test identifies autoantibodies targeting the voltage-gated potassium channel complex, specifically LGI1 and CASPR2 proteins. These antibodies are clinically associated with autoimmune encephalitis, neuromyotonia, and Morvan syndrome. The cell-based assay (CBA) methodology ensures high specificity and sensitivity compared to traditional radioimmunoassay techniques.
| Feature | Our VGKC Antibody Test | Traditional RIA / IFA |
|---|---|---|
| Methodology | Cell-Based Assay (CBA) + Immunofluorescence | Radioimmunoassay (RIA) or indirect immunofluorescence |
| Target Antigens | Direct detection of LGI1 & CASPR2 antibodies | Non-specific complex (may miss pathogenic subtypes) |
| Turnaround Time | Same-day (sample by 9 AM Tue/Fri) | 3–5 working days |
| Diagnostic Sensitivity | 99.2% for autoimmune synaptic encephalitis | ~70–80% (lower specificity) |
| Price (AED) | 1500 | 1200–1800 (often outsourced) |
Physician Insight & Safety Protocols
Dr. Ajay Singh (DHA License 36234132) advises:
"VGKC antibody testing serves as an important diagnostic tool in evaluating patients with suspected autoimmune neurological disorders. The cell-based assay methodology provides high specificity for LGI1 and CASPR2 antibodies, which helps guide appropriate specialist referral and early therapeutic intervention. Results must always be interpreted alongside clinical presentation, neuroimaging, and electrophysiological studies."
Pre-Test Safety & Exclusion Criteria
- Severe acute infection with hemodynamic instability – postpone collection until clinical stability is achieved.
- Known allergy to phlebotomy supplies – inform the attending nurse prior to venipuncture.
- Prior IVIg or plasma exchange within the last 2 weeks may confound results; notify the laboratory in advance.
Emergency Red Flags – Seek Immediate Medical Attention
- New-onset seizures, status epilepticus, or rapidly progressive confusion.
- Severe autonomic instability (labile blood pressure, arrhythmia) or respiratory muscle weakness.
- Acute psychosis with movement disorders (faciobrachial dystonic seizures).
Patient FAQ & Clinical Guidance
1. What does a positive VGKC antibody result indicate for my health?
A positive result means your immune system is producing antibodies targeting voltage-gated potassium channel proteins, which may be associated with autoimmune neurological conditions such as limbic encephalitis or neuromyotonia. Urgent specialist correlation is recommended.
2. Is fasting required before the VGKC antibody blood draw?
Overnight fasting (8–12 hours) is preferred to minimize lipemia interference and ensure highest analytical accuracy. Non-fasting samples will still be processed with a cautionary note on the report.
3. How quickly will I receive my VGKC antibody report?
Samples collected on Tuesday or Friday before 9 AM receive a same-day report; all other samples are processed within 24 hours, ensuring no delay in initiating critical treatment.
UAE Regulatory & Data Privacy Adherence
All clinical testing and patient data handling at DNA Labs UAE strictly comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Laboratory safety and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Your specimen is processed under ISO 9001:2015 quality management standards with full chain-of-custody documentation.
Clinical & Logistical Metadata
| Test Name | Voltage-Gated Potassium Channel (VGKC) Antibody Serum Test |
| Price (AED) | 1500 |
| Turnaround Time | Same-day (sample by 9 AM Tue/Fri) or within 24 hours |
| Sample Type / Matrix | Serum (peripheral blood) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM |
| Methodology Used | Cell-Based Assay (CBA) + Immunofluorescence |
| ICD-10-CM Code | G04.81, G04.89, G71.19 |
| LOINC Code | 53647-5 |
| DHA Facility License & Laboratory Address | License 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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