Test Price
900 AED✅ Home Collection Available
Aquaporin-4 (AQP4) Antibody Test for Neuromyelitis Optica in UAE | 900 AED
Executive Summary & Core Metrics
Executive Summary:
Our DHA-licensed facility (DHA License 1143) offers the gold-standard Aquaporin-4 IgG antibody test using cell-based indirect immunofluorescence (CBA-IFA) for definitive NMOSD diagnosis. This test provides high diagnostic sensitivity and specificity to differentiate Neuromyelitis Optica Spectrum Disorder from multiple sclerosis.
- Accuracy Guarantee: >90% Sensitivity and 99% Specificity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by a DHA-certified general practitioner.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731 (all major UAE insurers accepted).
Same-day reporting for samples received by 9 AM (Tue/Fri). Hospital collection only.
Test Overview & Methodology
The AQP4 antibody test detects IgG autoantibodies targeting the aquaporin-4 water channel – the pathogenic hallmark of Neuromyelitis Optica Spectrum Disorder (NMOSD). This test differentiates NMOSD from multiple sclerosis with high specificity and is essential for guiding lifelong immunotherapy. The gold-standard method is cell-based indirect immunofluorescence (CBA-IFA).
| Feature | Our Test (CBA-IFA) | Traditional ELISA |
|---|---|---|
| Methodology | Cell-Based Indirect Immunofluorescence | Enzyme-Linked Immunosorbent Assay |
| Sensitivity | >90% | <60% |
| Specificity | 99% | 95% |
| Turnaround Time | Same Day (sample by 9 AM) | 3–5 Days |
| Price | 900 AED | Variable |
| Sample | 2 mL serum or 1 mL CSF (hospital collection) | Serum only (commonly) |
Physician Insight & Safety Protocols
Dr. Ajay Singh, General Practitioner (DHA Registration ID: 36234132): “As a clinician managing autoimmune conditions, I want you to know that the AQP4 antibody test is a powerful diagnostic tool. A positive result must be interpreted alongside MRI findings and clinical history. I am here to guide you through the process; never modify your prescribed therapy without consulting your healthcare provider.”
Safety & Exclusion Criteria
Exclusion: This test is not indicated for asymptomatic individuals or routine screening. Only order if clinical suspicion of optic neuritis, longitudinally extensive transverse myelitis, or brainstem syndrome persists. Known hypersensitivity to phlebotomy materials (rare) is a contraindication.
Interfering Factors: Recent plasmapheresis, IVIG, or certain biologics may temporarily suppress antibody titers; inform our lab.
🚨 Emergency Red Flags: If you experience sudden vision loss, acute bilateral leg weakness, or breathing difficulty, proceed to your nearest Emergency Department immediately.
Patient FAQ & Clinical Guidance
1. What is an AQP4 antibody test and why is it needed?
The AQP4 antibody test detects autoimmune antibodies targeting aquaporin-4 water channels, diagnosing neuromyelitis optica spectrum disorder. This highly specific biomarker distinguishes NMOSD from multiple sclerosis and guides urgent immunotherapy to prevent paralysis and blindness.
2. How should I prepare for the test?
No fasting or dietary restrictions are required; continue your regular medications exactly as prescribed by your neurologist. Sample collection (serum or CSF) is performed in a hospital setting only – home phlebotomy is not available for this test due to the invasive nature of CSF collection and safety protocols.
3. What does a positive AQP4 antibody result mean?
A positive result indicates a high probability of Neuromyelitis Optica Spectrum Disorder, but must be correlated with clinical symptoms and MRI by your doctor. It is not a false positive cancer marker; it reflects an autoimmune attack on the central nervous system requiring long-term immunosuppression.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Security: DNA Labs UAE strictly complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. All patient health information is encrypted and handled in accordance with UAE healthcare regulations.
Accreditation: ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). DHA facility licensed under number 1143. Laboratory operations meet international standards for diagnostic testing.
Clinical & Logistical Metadata
| Test Name | Aquaporin-4 (AQP4) Antibody, IgG (Serum/CSF) |
| Price (AED) | 900 |
| Turnaround Time | Same day (sample received by 9 AM on Tue/Fri) |
| Sample Type / Matrix | 2 mL serum (SST tube) or 1 mL CSF – Hospital Extraction Only |
| Methodology Used | Cell-Based Indirect Immunofluorescence (CBA-IFA) |
| ICD-10-CM Code | G36.0 (Neuromyelitis optica [Devic]) |
| LOINC Code | 54294-9 (Aquaporin 4 Ab [Presence] in Serum) |
| DHA Facility License & Address | License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians