Test Price
800 AED✅ Home Collection Available
Smooth Muscle Antibody (ASMA) IFA in Dilutions Test in UAE | 800 AED | DHA Certified
Executive Summary & Core Metrics
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 15189 & ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM – 11 PM) by DHA-licensed professionals.
- Clinical Guidance: Complimentary telephonic post-test clinical guidance for result interpretation by DHA-licensed specialists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Smooth Muscle Antibody (ASMA) IFA in Dilutions test detects and quantifies autoantibodies directed against smooth muscle proteins, primarily actin (F-actin). It is a cornerstone serological marker for autoimmune liver diseases such as autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC). The immunofluorescence titration provides a semi‑quantitative result critical for diagnosis, prognosis, and monitoring under stringent DHA and ISO 15189 quality standards.
| Feature | Our Test (ASMA IFA with Titers) | Closest Alternative (ASMA ELISA Qualitative) |
|---|---|---|
| Precision & Clinical Depth | Semi‑quantitative titer (e.g., 1:40, 1:80, 1:160) with pattern recognition on HEp‑2 cells; gold‑standard for AIH diagnosis. | Binary positive/negative result; cannot differentiate low‑level reactivity or monitor disease activity. |
| Methodology | Immunofluorescence Assay (IFA) on primate liver/stomach/kidney composite substrate, confirmed by HEp‑2 cell substrate. | Enzyme‑Linked Immunosorbent Assay (ELISA) – may miss conformational epitopes. |
| Turnaround Time | Next day by 11 AM (same‑day batch processing) | 2 – 3 days |
| Sample Requirement | 3 mL serum (minimum 1.5 mL) from SST; overnight fasting preferred | Serum (may accept plasma in some labs) |
Physician Insight & Safety Protocols
“A positive ASMA IFA titer is a significant marker for autoimmune hepatitis, but it requires careful correlation with liver function tests, IgG levels, and clinical presentation. As a GP, I emphasize that a single result is just one piece of the diagnostic puzzle. Patients should never adjust their prescribed medications without direct consultation with their specialist. We ensure every result is accompanied by a clear telephonic explanation to guide the next steps.”
— Dr. Ajay Singh, General Practitioner, DHA Registration ID: 36234132
Medication Advisory
Do not discontinue any prescribed immunosuppressive therapy (including corticosteroids or azathioprine) without direct consultation with your referring physician. Abrupt cessation of these medications may trigger severe autoimmune flares or hepatic decompensation.
Exclusion Criteria & ER Red Flags
- Exclusion: Recent vaccination (within 2 weeks), active systemic infection, known hemolytic anemia (can interfere with IFA reading).
- Red Flags: Seek emergency care if you develop new‑onset jaundice, severe right‑upper‑quadrant pain, confusion, or sudden ascites while waiting for results.
- If the sample is hemolyzed or lipemic, recollection may be requested to ensure accuracy.
Patient FAQ & Clinical Guidance
1. What does the ASMA IFA test detect, and what conditions does it help diagnose?
The ASMA IFA detects antibodies against smooth muscle, aiding diagnosis of autoimmune hepatitis and primary biliary cholangitis. A positive titer (≥1:40) with characteristic staining patterns strongly supports autoimmune hepatitis, especially when combined with elevated liver enzymes and IgG. Low‑titer positives may also appear in chronic viral hepatitis or drug‑induced liver injury, so results must be interpreted by a specialist.
2. Why is overnight fasting preferred before the ASMA blood draw?
Fasting prevents lipemic interference that can obscure the immunofluorescence pattern, ensuring a clearer and more accurate titer determination. While not mandatory for the antibody reaction itself, a non‑fasting sample may yield a mild background fluorescence that complicates reading. Drink plain water; avoid fatty meals for 8‑12 hours prior.
3. How does the VIP home collection service work and is it safe?
Our DHA‑licensed phlebotomists arrive at your doorstep using an ISO‑certified cold‑chain transport kit, maintaining specimen integrity from vein to lab. The process follows sterile, hospital‑grade protocols; all staff hold valid DHA licenses. The sample is transported in validated temperature‑controlled containers (2‑8°C) immediately after collection. Results are delivered electronically next day, and you receive a telephonic clinical guidance call to discuss implications.
UAE Regulatory & Data Privacy Adherence
Compliance & Data Sovereignty
This service strictly adheres to the UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical data is encrypted and stored on UAE-based sovereign clouds. Patient consent protocols comply with Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is fully licensed by the Dubai Health Authority (DHA) under Facility License Number 1143.
Clinical & Logistical Metadata
| Test Name | Smooth Muscle Antibody (ASMA) IFA in Dilutions |
| Price (AED) | 800 |
| Turnaround Time | Next day by 11 AM (batch processing) |
| Sample Type / Matrix | Serum (SST, 3 mL, min 1.5 mL). Overnight fasting preferred. |
| Methodology Used | Immunofluorescence Assay (IFA) on primate liver/kidney/stomach composite and HEp‑2 cell substrate with titer quantification. |
| ICD-10-CM Code | K75.4 (Autoimmune hepatitis), K74.3 (Primary biliary cholangitis), R74.8 (Abnormal serum enzyme levels) |
| LOINC Code | 16772-8 (Smooth Muscle Ab [Titer] in Serum) |
| DHA Facility License & Laboratory Address | Facility License: 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
Call / WhatsApp: +971 54 548 8731 | 8 AM – 11 PM daily
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