Test Price
600 AEDโ Home Collection Available
Anti-dsDNA Antibody Test (Crithidia IFA Dilutions) in UAE | 600 AED | DHA Certified
Executive Summary & Core Metrics
- โ 99.9% Diagnostic Sensitivity via ISO 15189 / 9001:2015 certified processing and Crithidia IFA methodology.
- โ Premium Logistics โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, available daily from 8 AM to 11 PM.
- โ Clinical Guidance โ Telephonic post-test clinical correlation support by Dr. Ajay Singh (DHA: 36234132).
- โ Insurance โ Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The Anti-dsDNA Antibody (Crithidia IFA Dilutions) test is the definitive serological assay for the diagnosis and monitoring of systemic lupus erythematosus (SLE). By using the Crithidia luciliae immunofluorescence method, it uniquely identifies high-avidity IgG autoantibodies against double-stranded DNA with minimal cross-reactivity, ensuring superior clinical specificity.
| Feature | Our Test (Crithidia IFA Dilutions) | Standard ELISA Anti-dsDNA |
|---|---|---|
| Methodology | Immunofluorescence (Crithidia luciliae substrat) | Enzyme-linked immunosorbent assay |
| Specificity for SLE | Very high (95โ99%) โ only high-avidity IgG | Moderate (80โ90%) โ may detect low-avidity/transient antibodies |
| Turnaround Time | Next day (sample by 11 AM) | 2โ3 days |
| Cost | 600 AED | ~400โ500 AED |
Physician Insight & Safety Protocols
Dr. Ajay Singh (General Practitioner, DHA: 36234132) comments: โThe Crithidia IFA remains the gold standard for confirming SLE-specific anti-dsDNA antibodies. A positive result, particularly at titers โฅ1:10, must be correlated with clinical features such as malar rash, arthritis, or nephritis. Always consult a rheumatologist for a comprehensive management plan.โ
Medication Advisory
โ ๏ธ Important Notice
Do not discontinue any prescribed immunosuppressants, corticosteroids, or antimalarials without explicit guidance from your treating physician. Abrupt cessation can trigger disease flares.
Patient Exclusion & Safety Criteria
Exclusion Criteria & Emergency Red Flags
- Phlebotomy is contraindicated in patients with known severe bleeding disorders or those on high-dose anticoagulants without prior medical clearance.
- Seek immediate emergency care if you experience severe pain, significant swelling, persistent bleeding, dizziness, or signs of infection after blood collection.
- This test is not offered to minors without explicit parental or guardian consent, in full compliance with UAE Federal Decree-Law No. 4 of 2016 on Medical Liability and the Emirateโs healthcare consent statutes.
Patient FAQ & Clinical Guidance
1. What is the clinical significance of the anti-dsDNA antibody test?
Key Insight: Anti-dsDNA antibodies detected by Crithidia IFA are highly specific for systemic lupus erythematosus and often correlate with disease activity, particularly lupus nephritis.
High-avidity IgG anti-dsDNA is a hallmark of SLE; a positive result at titers โฅ1:10 supports the diagnosis when interpreted alongside ANA patterns and clinical criteria. Serial monitoring can help assess treatment response and predict flares.
2. Why is the Crithidia IFA method preferred over standard ELISA for anti-dsDNA?
Key Insight: Crithidia IFA provides superior specificity (up to 99%) by selectively detecting high-avidity anti-dsDNA antibodies, minimizing false positives common in ELISA assays.
The Crithidia luciliae kinetoplast contains pure, concentrated dsDNA without histone or ssDNA contamination, making it the confirmatory method recommended by ACR/EULAR guidelines. This is especially crucial when ELISA yields borderline or discrepant results.
3. How should I prepare for the anti-dsDNA test in the UAE?
Key Insight: Overnight fasting is preferred but not mandatory; no medication adjustments are required unless specifically instructed by your physician.
A 3 mL serum sample is collected via our ISO-certified cold-chain home collection service. Specimens must arrive by 11 AM for same-day processing and next-day reporting. Contact WhatsApp +971 54 548 8731 to schedule your VIP mobile phlebotomy.
UAE Regulatory & Data Privacy Adherence
Our Commitment to Compliance
- All patient data is processed in strict accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Clinical laboratory operations are licensed under DHA Facility License No. 1143 and adhere to ISO 15189:2012 quality standards. Our physical address is Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
- Results are intended for clinical guidance and must be interpreted by a DHA-licensed physician.
Clinical & Logistical Metadata
| Test Name | Anti-dsDNA Antibody (Crithidia IFA Dilutions) |
| Price (AED) | 600 |
| Turnaround Time | Next Day (sample by 11 AM) |
| Sample Type / Matrix | Peripheral Blood Serum |
| Methodology Used | Indirect Immunofluorescence (Crithidia luciliae) |
| ICD-10-CM Code | M32.9 |
| LOINC Code | 5133-0 |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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