SCA-17 (Spinocerebellar Ataxia) TBP Gene Mutation Test in UAE | 800 AED | DNA Labs UAE

Executive Summary & Core Metrics

Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited processing using validated PCR and capillary electrophoresis.
Premium Logistics: Complimentary VIP mobile phlebotomy and temperature-controlled home collection (4 mL EDTA whole blood, available daily 8 AM–11 PM) by DHA-licensed nurses.
Clinical Guidance: Complimentary telephonic post-test interpretation by a Consultant Medical Genetics.
Insurance Support: Direct billing verification via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

This advanced genetic test identifies abnormal CAG/CAA trinucleotide repeat expansions in the TBP gene, confirming a clinical diagnosis of spinocerebellar ataxia type 17 (SCA-17), a rare adult-onset neurodegenerative movement disorder. Results guide neurologists, medical geneticists, and family planning decisions with definitive molecular evidence.

Feature	DNA Labs UAE – SCA-17 Premium	Closest Alternative
Methodology	PCR + Capillary Electrophoresis Fragment Analysis (ISO 9001:2015)	Older PCR with gel or Sanger sequencing (lower resolution)
Sensitivity for Repeat Expansions	99.9% for CAG expansions with exact sizing	>95%, may miss low-abundant expansions
Turnaround Time	10–12 Business Days (Express 7 Days Available)	14–21 Days
Home Collection	24/7 Cold-Chain VIP Mobile Phlebotomy Included	Clinic Collection Only
Price	800 AED (All-Inclusive)	900–1,200 AED

Physician Insight & Safety Protocols

“As a Consultant Medical Genetics with extensive experience in hereditary ataxias, I emphasize that a positive SCA-17 test provides definitive molecular confirmation of the TBP expansion. However, it must be interpreted alongside detailed clinical examination and family history. Early diagnosis allows for tailored multidisciplinary care, genetic counseling, and informed family planning. This test is a cornerstone of precision neurology, not a standalone verdict.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)

⚠ Medication Warning

Do not discontinue prescribed medications (e.g., antiepileptics, neuroleptics, or antidepressants) without consulting your doctor. Abrupt withdrawal can exacerbate ataxia or trigger severe neurological deterioration.

Exclusion Criteria & ER Red Flags (Do Not Proceed with Home Collection If):

Patient is a minor (under 18) without a legal guardian’s informed consent per UAE Medical Liability Law.
Patient has active bleeding disorder or platelet count <50,000/µL.
Patient is on high-dose anticoagulation (e.g., warfarin with INR >3.5, or therapeutic heparin) without prior physician clearance.
Acute fever (>38.5°C), sepsis, or altered consciousness – refer to emergency.
Known allergy to latex or chlorhexidine (alternative kit available upon request).

Patient FAQ & Clinical Guidance

1. What is the SCA-17 TBP gene mutation test and why is it ordered?

The SCA-17 TBP gene mutation test detects pathogenic expansions in the TBP gene causing spinocerebellar ataxia type 17, a progressive neurodegenerative disorder. It is ordered when a patient shows adult-onset ataxia, chorea, or cognitive decline, and helps confirm the diagnosis, guide treatment, and inform family members about their genetic risk.

2. How is the home blood collection performed and is it safe?

A DHA-licensed nurse arrives at your home in a temperature-controlled medical vehicle and draws 4 mL of blood from your arm vein using a lavender-top EDTA tube. The sample is immediately placed in a validated cold-chain transport (2–8°C) and delivered to our ISO-certified lab within hours, ensuring zero degradation. The procedure is safe and follows strict infection control protocols.

3. What do my results mean and how will I receive them?

A report indicating the number of CAG repeats and whether it falls into normal (<43), intermediate, or pathogenic (≥49) range is encrypted and shared securely via email or the DHA-approved patient portal. Our clinical team schedules a teleconsultation to interpret the findings, discuss implications for family members, and advise on next steps with a neurologist.

UAE Regulatory & Data Privacy Adherence

Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) ensures your genetic data is handled with strict confidentiality.
Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields governs secure electronic health records.
Federal Decree-Law No. 4 of 2016 on Medical Liability ensures patient safety and informed consent standards.
All clinical procedures comply with Dubai Healthcare City (DHCC) and DHA regulations.

Clinical & Logistical Metadata

Test Name	SCA-17 (TBP) Gene Mutation Test
Price (AED)	800 AED
Turnaround Time	10–12 Business Days (Express 7 Days Available)
Sample Type / Matrix	4 mL EDTA Whole Blood (Peripheral Venous)
Methodology Used	PCR + Capillary Electrophoresis Fragment Analysis
ICD-10-CM Code	G11.2
LOINC Code	69057-7
DHA Facility License & Laboratory Address	DHA License No: 1143 \| DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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