Test Price
2,800 AED✅ Home Collection Available
HBA2 Gene (Alpha Thalassemia) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Sequencing Laboratory.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, accessible daily from 8 AM to 11 PM.
- Clinical Guidance: Complimentary telephonic post-test interpretation by a DHA-licensed Consultant Medical Geneticist.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731; most UAE plans accepted.
Test Overview & Methodology
This advanced diagnostic assay employs next-generation sequencing (NGS) technology to interrogate the entire HBA2 gene, detecting deletions, point mutations, and copy number variations with high analytical sensitivity. The test delivers definitive carrier status classification and disease risk assessment for alpha thalassemia, enabling informed reproductive planning and individualized clinical surveillance.
| Feature | Our Test (NGS Full Gene) | Conventional Alternative |
|---|---|---|
| Precision | 99.9% sensitivity for rare mutations | Limited to common deletions only |
| Method | Next-Generation Sequencing (Illumina) | Gap-PCR / MLPA |
| Turnaround Time | 3–4 Weeks | 2–3 Weeks |
| Coverage | Entire HBA2 gene (promoter to 3' UTR) | Only known deletions/mutations |
Physician Insight & Safety Protocols
“NGS-based HBA2 analysis must always be integrated with a complete blood count, iron studies, and a three-generation family pedigree. I regularly identify silent alpha-thalassemia carriers who would otherwise remain undiagnosed until an affected child is born. This test enables precise genetic counseling and informed reproductive choices. No molecular result, however comprehensive, should replace a thorough clinical evaluation with physical examination and hematological correlation.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory Guidance for Patients
Important Pre-Test Considerations
Do not interpret raw genetic data without professional counseling. All results require contextual analysis by a qualified clinical geneticist. Continue all prescribed medications as directed by your primary physician unless explicitly advised otherwise by your genetic counselor. Inform your geneticist about any blood transfusions received within the past three months, as donor DNA may interfere with sequence interpretation.
Patient Safety: Exclusion Criteria & Red Flags
Contraindications for Sample Collection
- Exclusion: Active hemolytic crisis or acute febrile illness at time of phlebotomy.
- Exclusion: Blood transfusion within the last 3 months (risk of chimeric DNA interference).
- Exclusion: Hemodynamically unstable patients with severe anemia, chest pain, or dyspnea.
- ER Red Flag: New or worsening severe pallor, tachycardia, splenic sequestration, or history of hydrops fetalis.
- ER Red Flag: Symptoms of hyperhemolysis (dark urine, jaundice) requiring urgent medical evaluation.
Patient FAQ & Clinical Guidance
1. What is the HBA2 Genetic Test and why is it recommended?
This NGS assay sequences the entire HBA2 gene, detecting both common and rare alpha-thalassemia mutations with greater than 99% diagnostic accuracy. It is recommended for couples planning a pregnancy, individuals presenting with unexplained microcytic anemia, and those with a documented family history of thalassemia. The test distinguishes between silent carrier status, alpha-thalassemia trait, and HbH disease, thereby guiding reproductive options, prenatal diagnosis, and long-term hematological surveillance.
2. Can I use a single drop of blood on an FTA card for this test?
Yes, our laboratory accepts whole blood, extracted DNA, or a single drop of blood dried on an FTA card with equivalent diagnostic sensitivity. The FTA card offers a convenient, room-temperature stable option for home collection, eliminating the need for cold-chain shipment while preserving DNA integrity. We validate the same analytical performance whether you choose venipuncture or a minimal-pain finger-prick method.
3. How are results interpreted and what follow-up is required?
Results are interpreted by a DHA-licensed Consultant Medical Geneticist who correlates sequencing findings with your complete blood count, ferritin level, and family pedigree. If you are identified as a silent carrier, no medical treatment is necessary, but genetic counseling is strongly recommended for future family planning. A confirmed alpha-thalassemia trait or HbH disease diagnosis warrants regular monitoring for anemia and iron overload; we provide a post-test telehealth consultation to explain your personalized management plan and coordinate any necessary specialist referrals.
UAE Regulatory & Data Privacy Adherence
- Data Protection: All patient genetic data is processed and stored in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Clinical Safety: Sampling procedures and patient consent protocols adhere strictly to Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Laboratory Certification: ISO 9001:2015 certified sequencing facility operating under DHA Facility License Number 1143.
- Confidentiality: Genomic data is encrypted, access-restricted, and never shared with third parties without explicit written patient consent.
Clinical & Logistical Metadata
| Test Name | HBA2 Gene (Alpha Thalassemia) Genetic Test – Next Generation Sequencing (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (Peripheral), Extracted DNA, or Dried Blood Spot (FTA Card) — VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available Daily 8 AM – 11 PM |
| Methodology Used | Next-Generation Sequencing (Illumina) – Full gene coverage from promoter to 3' UTR |
| ICD-10-CM Code | D56.0 |
| LOINC Code | 21639-0 |
| DHA Facility License & Laboratory Address | DHA License Number 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians