Test Price
2,800 AED✅ Home Collection Available
SLC24A5 Gene Oculocutaneous Nonsyndromic Albinism Genetic Test – Dubai Healthcare City
Executive Summary & Core Metrics
This Next-Generation Sequencing (NGS) test analyzes the SLC24A5 gene to detect pathogenic variants associated with oculocutaneous nonsyndromic albinism type 6 (OCA6). The assay provides 99.9% diagnostic sensitivity through ISO-accredited processing and rigorous bioinformatic validation.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance from a Consultant Medical Genetics specialist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This diagnostic assay utilizes Illumina Next-Generation Sequencing to achieve comprehensive coverage of the SLC24A5 gene, including detection of single nucleotide variants (SNVs), small insertions/deletions (indels), and copy number variants (CNVs). The test is indicated for individuals presenting with clinical features of oculocutaneous albinism—such as photophobia, nystagmus, hypopigmented fundi, and reduced visual acuity—and for those with a family history suggestive of autosomal recessive inheritance.
| Feature | Our NGS OCA6 Test | Single‑Gene Sanger Alternative |
|---|---|---|
| Precision | Full gene coverage, CNV & SNV detection | Limited to known hotspot variants |
| Methodology | Illumina NGS with bioinformatic validation | Sanger sequencing |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
Physician Insight & Safety Protocols
"As a Consultant Medical Genetics specialist managing inherited disorders, I emphasize that a positive SLC24A5 variant must be correlated with clinical ophthalmologic and dermatologic findings. This NGS test provides high-confidence molecular confirmation but does not replace a comprehensive clinical evaluation. Results should guide a personalized management plan in consultation with a genetic counselor and ophthalmologist."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
⚠ Medication & Pre-test Advisory
Do not discontinue or alter any prescribed medication regimen without prior consultation with your attending physician. The genetic test itself does not require any medication adjustment unless specifically instructed by your doctor.
Safety Exclusions & Emergency Red Flags
- Individuals under 18 years of age require written guardian consent in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Inability to provide informed consent or presence of severe cognitive impairment.
- Active bleeding disorder or current anticoagulant therapy that contraindicates even a capillary blood spot collection (FTA card).
- If you experience sudden vision loss, severe eye pain, or signs of allergic reaction post-collection, seek immediate emergency care.
Patient FAQ & Clinical Guidance
1. What does this SLC24A5 NGS test detect, and who should consider it?
This assay identifies pathogenic and likely pathogenic variants in the SLC24A5 gene responsible for oculocutaneous nonsyndromic albinism type 6 (OCA6). It is indicated for individuals presenting with clinical signs of albinism—photophobia, nystagmus, hypopigmented fundi, and reduced visual acuity—and those with a family history consistent with autosomal recessive inheritance. Genetic counseling is recommended before and after testing.
2. How is the sample collected, and is fasting required?
A certified phlebotomist collects either 2–3 mL of whole blood in an EDTA tube, extracted DNA, or a few drops of blood on an FTA card during our VIP home visit service (available daily from 8 AM to 11 PM). Fasting is not required, and you may continue all current medications unless your physician instructs otherwise.
3. Does health insurance cover this genetic test in the UAE?
Many insurance providers in the UAE offer coverage for genetic testing when deemed medically necessary. Please forward your insurance card via WhatsApp to +971 54 548 8731 for eligibility verification before your appointment. Direct billing options are available for approved policies.
4. How long does it take to receive results, and how will they be delivered?
The turnaround time is 3 to 4 weeks from sample receipt. Results are delivered via a secure digital portal and include a detailed clinical report with variant classification per ACMG guidelines. A telephonic post-test consultation with our Consultant Medical Genetics specialist is provided for result interpretation.
UAE Regulatory & Data Privacy Adherence
This diagnostic service operates in full compliance with the following UAE federal frameworks:
- Data Protection: Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) — ensuring secure processing of all personal health information with explicit consent and data minimization protocols.
- Health Data Security: Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields — governing the secure storage, transmission, and access of electronic health records and genetic data.
- Clinical Safety & Patient Consent: Federal Decree-Law No. 4 of 2016 on Medical Liability — establishing informed consent standards, professional accountability, and patient safety requirements for all diagnostic procedures.
DNA Labs UAE is a DHA-licensed facility (License No. 1143) operating under the jurisdiction of the Dubai Healthcare City Authority. All genetic testing is performed in ISO-accredited laboratories with stringent quality assurance protocols.
Clinical & Logistical Metadata
| Test Name | SLC24A5 Gene Oculocutaneous Nonsyndromic Albinism (OCA6) NGS Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card Blood Spot |
| Methodology Used | Illumina Next-Generation Sequencing (NGS) with Bioinformatic CNV Detection |
| ICD-10-CM Code | E70.33 (Oculocutaneous albinism) |
| LOINC Code | 94494-2 (SLC24A5 gene mutation analysis in Blood or Tissue by Molecular genetics method) |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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