Test Price
2,200 AED✅ Home Collection Available
Cortisol Free Serum Test in UAE | 2200 AED | DHA-Regulated Endocrine Assessment
Executive Summary: The Cortisol Free Serum Test utilises ultra-sensitive LC-MS/MS to quantify biologically active unbound cortisol for accurate adrenal function evaluation. This gold-standard assay eliminates cross-reactivity issues seen with total cortisol immunoassays, delivering 99.9% diagnostic sensitivity.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM–11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in Result Interpretation by DHA-Licensed General Practitioner.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Cortisol Free Serum Test precisely quantifies biologically active, unbound cortisol using LC-MS/MS, the gold standard for adrenal function assessment. This test is essential for diagnosing subtle hypercortisolism (Cushing's syndrome) or adrenal insufficiency, offering superior specificity over total cortisol immunoassays that are confounded by cortisol-binding globulin fluctuations.
| Feature | Our Test (Cortisol Free Serum) | Typical Immunoassay (Total Cortisol) |
|---|---|---|
| Precision | Ultra-sensitive LC-MS/MS; no cross-reactivity | Moderate; may over/under-estimate due to binding proteins |
| Methodology | Liquid Chromatography-Tandem Mass Spectrometry | Chemiluminescent Immunoassay (CLIA) / ECLIA |
| Turnaround Time | 2–3 weeks (send-out, high complexity) | 1–2 days (faster, less specific) |
| Clinical Utility | Gold standard for free cortisol in adrenal disorders, pregnancy, oral contraceptive use | Screening only; influenced by altered binding globulins |
Physician Insight & Safety Protocols
“The Cortisol Free Serum test by LC-MS/MS provides a highly accurate measure of bioactive cortisol, circumventing the binding-protein interference that plagues traditional immunoassays. Interpretation must always be correlated with clinical presentation, dynamic testing, and imaging. Patients should never alter corticosteroid therapy without specialist guidance.” – Dr. Ajay Singh, General Practitioner | DHA Registration ID: 36234132
Critical Medication Warning & Safety Exclusion
⚠️ Medication Warning: Do not discontinue, adjust, or start any prescribed corticosteroid or hormonal medication without consulting your doctor. Abrupt cessation of glucocorticoids may trigger life‑threatening adrenal crisis.
- Sample collection must not use SST gel barrier tubes – red‑top (no additive) tubes only.
- Specimen must be shipped refrigerated or frozen; improper transport invalidates results.
- Test Send Out Consent Form (Form 35) is mandatory; missing form will delay processing.
- Do not proceed if the patient exhibits signs of acute adrenal crisis: severe hypotension, vomiting, altered consciousness, or sudden abdominal pain – seek ER immediately.
Patient FAQ & Clinical Guidance
1. What makes free cortisol measurement more accurate than standard total cortisol testing?
Free cortisol quantified by LC-MS/MS excludes protein-bound fractions, giving a pure picture of bioactive cortisol. This avoids overestimation from elevated binding globulins during pregnancy or oestrogen therapy, and underestimation in low-protein states.
2. How does LC-MS/MS technology improve reliability for hormone analysis?
LC-MS/MS directly measures the cortisol molecule by mass and retention time, eliminating cross‑reactivity with similar steroids. This yields unparalleled specificity and sensitivity, essential for detecting subtle adrenal dysfunction.
3. Are there any special preparations required before the blood draw for this test?
Fasting is not mandatory. However, you must inform the phlebotomist about all medications, supplements (especially biotin), and recent corticosteroid use, as these can influence cortisol levels or interfere with the assay methodology.
UAE Regulatory & Data Privacy Adherence
Your data is protected under: Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All results are encrypted and handled with strict confidentiality. Clinical safety and consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | Cortisol Free Serum Test |
| Price (AED) | 2,200 AED |
| Turnaround Time | 2–3 weeks |
| Sample Type / Matrix | Serum |
| Methodology Used | LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) |
| ICD-10-CM Code | E27.9 |
| LOINC Code | 14634-3 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (DNA Labs UAE) |
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