Test Price
700 AEDโ Home Collection Available
Androstenedione Stimulation by ACTH Test in Dubai, UAE | 700 AED | DNA Labs UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 15189 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM). Note: ACTH (Synacthen) administration must be performed by your treating physician at a medical facility.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The Androstenedione Stimulation by ACTH test evaluates adrenal gland function by measuring androstenedione levels after synthetic ACTH administration. This dynamic endocrine assessment aids in diagnosing congenital adrenal hyperplasia, adrenal insufficiency, and related disorders of steroidogenesis. The test involves a baseline blood draw, intravenous administration of 250 ยตg Synacthen (synthetic ACTH) by a physician, followed by a timed post-stimulation blood draw. Androstenedione is quantified using a high-specificity chemiluminescent immunoassay (CLIA).
| Feature | Androstenedione ACTH Stimulation (CLIA) | LC-MS/MS Steroid Panel |
|---|---|---|
| Analytical Platform | Chemiluminescent Immunoassay (CLIA) with dynamic ACTH stimulation | Liquid Chromatography-Tandem Mass Spectrometry โ single sample, no stimulation |
| Functional Assessment | Yes โ dynamic adrenal reserve evaluation post-Synacthen | No โ static steroid profile only |
| Turnaround Time | Same-day report (samples received by 4 PM Mon/Thu) | 3โ5 working days |
Physician Insight & Safety Protocols
Dr. Ajay Singh (General Practitioner, DHA License: 36234132) comments: "The ACTH stimulation test is a cornerstone for evaluating adrenal reserve. A normal androstenedione response provides reassurance of intact adrenal function. However, interpretation must always be correlated with clinical findings. Borderline or blunted responses warrant close endocrine follow-up and possible repeat testing."
Medication Advisory
Do not modify or discontinue any prescribed medications, including corticosteroids or hormone therapies, without explicit guidance from your treating physician. Abrupt cessation can precipitate adrenal crisis.
Exclusion Criteria & Emergency Red Flags
- Synacthen (synthetic ACTH) is not supplied by the laboratory; it must be prescribed and administered by your treating physician in a clinical setting.
- Known hypersensitivity to synthetic ACTH or any excipient in the injection formulation.
- History of severe allergic reaction or anaphylaxis to prior ACTH stimulation testing.
- Emergency warning signs of acute adrenal crisis: sudden severe abdominal pain, persistent vomiting, hypotension, altered consciousness, or extreme weakness. Seek immediate emergency medical attention.
Patient FAQ & Clinical Guidance
1. What is the Androstenedione Stimulation by ACTH test?
This dynamic endocrine test measures your adrenal glands' capacity to produce androstenedione following a standardized synthetic ACTH (Synacthen) injection. It helps diagnose congenital adrenal hyperplasia, adrenal insufficiency, and related steroidogenic disorders.
2. How should I prepare for this test?
Overnight fasting (8โ12 hours) is required. Your physician will place an intravenous cannula, collect a baseline blood sample, administer 250 ยตg Synacthen intravenously, and then collect a timed post-stimulation blood sample at 30 or 60 minutes. Inform your doctor about all medications you are taking.
3. When will I receive my results?
Reports are issued the same day if the laboratory receives your samples by 4:00 PM on Monday or Thursday. Results will be communicated via secure digital channels and discussed during a telephonic clinical guidance session.
4. What do my results mean?
A normal androstenedione rise after Synacthen indicates intact adrenal 17,20-lyase activity. A blunted or absent response may suggest adrenal insufficiency or enzyme deficiency (e.g., 21-hydroxylase deficiency). Your endocrinologist will interpret results in the context of your clinical presentation.
5. Is home collection available for this test?
Our VIP Mobile Phlebotomy service can collect blood samples at your home, but the Synacthen injection must be administered by your treating physician at a clinic or hospital. Please coordinate with both services for a seamless experience.
UAE Regulatory & Data Privacy Adherence
Your Data, Protected by Law
DNA Labs UAE operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical data transmitted, stored, and processed for this test is encrypted and access-controlled. Your consent is obtained prior to testing, and your rights to access, rectify, or delete your data are guaranteed under UAE law. Clinical safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | Androstenedione Stimulation by ACTH (Synacthen) Test |
| Price (AED) | 700 |
| Turnaround Time | Same-day (samples received by 4 PM Mon/Thu) |
| Sample Type / Matrix | Serum (baseline and 30โ60 min post-ACTH) |
| Methodology Used | Chemiluminescent Immunoassay (CLIA) |
| ICD-10-CM Code | E27.4 (Adrenal insufficiency), E25.0 (Congenital adrenal hyperplasia) |
| LOINC Code | 2142-3 (Androstenedione [Mass/volume] in Serum or Plasma) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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