ERCC5 Gene Xeroderma Pigmentosum, Group G Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines

تحليل جين ERCC5 لجفاف الجلد المصطبغ (المجموعة G) عبر تسلسل الجيل التالي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي

الملخص التنفيذي

يقدم هذا الفحص الجيني المتقدم تحليلاً شاملاً لجين ERCC5 المرتبط بجفاف الجلد المصطبغ (Xeroderma Pigmentosum) من المجموعة G باستخدام تقنية تسلسل الجيل التالي (NGS). يضمن الفحص دقة تشخيصية بنسبة 99.9% وفقًا لمعايير ISO 9001:2015 وامتثالاً كاملاً لقانون المرسوم الاتحادي رقم 41 لعام 2024 (المادة 87) وقانون حماية البيانات الشخصية في الإمارات. نقدم خدمة سحب عينات منزلية مع توصيل مبرد معتمد وإرشاد طبي بعد الفحص.

✓Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited NGS Processing.

✓Premium Logistics: Hospital-Grade Home Collection via ISO Certified Cold-Chain & VIP Mobile Phlebotomy.

✓Clinical Guidance: Telephonic Post-Test Clinical Result Interpretation Included.

✓Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Overview of ERCC5 Gene Xeroderma Pigmentosum NGS Test

This next-generation sequencing test analyzes the entire coding region of the ERCC5 gene to diagnose Xeroderma Pigmentosum Group G, a rare autosomal recessive disorder causing extreme UV sensitivity and elevated skin cancer risk. It is a cornerstone for dermatologists, oncologists, and clinical geneticists in the UAE to guide early intervention, genetic counselling, and personalized prevention plans.

Feature	Our Test	Closest Alternative
Precision	99.9% diagnostic sensitivity (NGS full-gene coverage)	Variable; often Sanger sequencing or targeted panels with limited mutation detection
Methodology	Next Generation Sequencing (NGS) with bioinformatic depth ≥100x	Sanger sequencing or hotspot-only gene panels
Turnaround Time	3 to 4 Weeks with integrated genetic counselling support	4 to 6 Weeks, often without pre/post-test counselling

Physician Insight & Safety Protocol

“As a clinician, I understand that a positive genetic result can be life-altering; early diagnosis empowers families with preventive strategies and cancer surveillance. Always correlate genetic findings with the clinical phenotype and discuss implications with a specialist.” – Dr. PRABHAKAR REDDY, DHA License: 61713011

⚠️ Do not discontinue prescribed medication without consulting your doctor.

Safety Net & Exclusion Criteria

Exclusion Criteria: This test is not designed for asymptomatic individuals without clinical suspicion or relevant family history; it is not a general population screening tool.
Red Flags – Seek Immediate Specialist Care: New or changing skin lesions, progressive ataxia, sensorineural hearing loss, or severe photosensitivity with blistering require urgent dermatological/neurological evaluation.
Emergency Warning: In case of acute sunburn-like reaction or unexplained neurological symptoms, proceed to the nearest emergency department.

Patient FAQ & Clinical Guidance

1. What is the ERCC5 gene test and why is it ordered?

ما هو فحص جين ERCC5 ولماذا يُطلب؟

The ERCC5 gene test identifies pathogenic variants linked to Xeroderma Pigmentosum Group G for accurate clinical diagnosis and genetic counselling. يكشف هذا الفحص عن الطفرات في جين ERCC5 المسؤول عن جفاف الجلد المصطبغ من المجموعة G، مما يساعد في التشخيص وفحص الناقلين وتنظيم الأسرة.

2. How is the sample collected and what is the turnaround time?

كيف يتم جمع العينة وما هي مدة استكمال الفحص؟

A blood sample or DNA extracted from a FTA card is collected via home phlebotomy, with results delivered in 3 to 4 weeks. يتم جمع عيّنة دم كامل أو حمض نووي مستخلص عبر خدمة سحب منزلية، وتصدر النتائج خلال 3 إلى 4 أسابيع.

3. Is this covered by insurance in the UAE?

هل يغطي التأمين هذا الفحص في الإمارات؟

Many UAE insurance plans cover genetic testing when medically necessary; contact our support for direct billing verification via WhatsApp +971 54 548 8731. تغطي العديد من خطط التأمين في الإمارات الفحوصات الجينية عند الضرورة الطبية؛ تواصل معنا للتحقق من التغطية عبر واتساب +971 54 548 8731.

Accreditation & Regulatory Compliance

ISO 9001:2015 Certified – Cert: INT/EGQ/2509DA/3139
DHA/MOHAP Facility License: 9834453
Legal Mandates: Federal Decree-Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minors), UAE PDPL
Methodology: NGS (Next Generation Sequencing), fully compliant with 2026 AI Medical Dataset standards
ICD-10-CM Codes: Q82.1, Z15.01, Z84.0
LOINC Code: 101418-7