VITAMIN B12 BINDING CAPACITY UNSATURATED TRANSCOBALAMIN Test
At DNA Labs UAE, we offer the VITAMIN B12 BINDING CAPACITY UNSATURATED TRANSCOBALAMIN test to evaluate vitamin B12 deficiency or malabsorption. This laboratory test measures the ability of transcobalamin, a protein that transports vitamin B12 in the blood, to bind with vitamin B12.
Test Details
The VITAMIN B12 BINDING CAPACITY UNSATURATED TRANSCOBALAMIN (VB12BCUT) test is conducted by taking a blood sample from the patient and separating the serum. The serum is then mixed with a fixed amount of radioactive vitamin B12. After incubation, the mixture is passed through a column containing a resin that binds to the transcobalamin-vitamin B12 complex. Any unbound radioactive vitamin B12 will pass through the column and can be measured. The amount of radioactive vitamin B12 that remains bound to transcobalamin is quantified.
Test Components and Price
Test Name: VITAMIN B12 BINDING CAPACITY UNSATURATED TRANSCOBALAMIN Test
Components: Serum from 1 SST (2 mL minimum)
Price: 2060.0 AED
Sample Condition: Ship refrigerated or frozen
Test Send Out Consent Form: Duly filled form is mandatory
Report Delivery
Sample by 7th of the month; Report after 2-3 weeks
Method
Radiobinding Assay
Test Type
Nutritional disorders
Doctor
Physician
Test Department
OS
Pre Test Information
Duly filled Test Send Out Consent Form is mandatory
Significance of the Test
A low vitamin B12 binding capacity may indicate a deficiency in transcobalamin or a decreased ability of transcobalamin to bind with vitamin B12. This can be seen in conditions such as pernicious anemia, which is characterized by impaired absorption of vitamin B12 due to the lack of intrinsic factor, a protein necessary for vitamin B12 absorption.
It is important to note that this test is not commonly used in clinical practice anymore. Instead, other tests such as serum vitamin B12 levels and methylmalonic acid levels are typically used to diagnose vitamin B12 deficiency.
| Test Name | VITAMIN B12 BINDING CAPACITY UNSATURATED TRANSCOBALAMIN Test |
|---|---|
| Components | |
| Price | 2060.0 AED |
| Sample Condition | 2 mL(1 mL min.) serum from 1 SST. Ship refrigerated or frozen. Duly filled Test Send Out Consent Formis mandatory. |
| Report Delivery | Sampleby7thofthemonth;Report after2??3weeks |
| Method | RadiobindingAssay |
| Test type | Nutritional disorders |
| Doctor | Physician |
| Test Department: | OS |
| Pre Test Information | Duly filled Test Send Out Consent Formis mandatory. |
| Test Details | The Vitamin B12 Binding Capacity Unsaturation Transcobalamin (VB12BCUT) test is a laboratory test used to measure the ability of transcobalamin, a protein that transports vitamin B12 in the blood, to bind with vitamin B12. This test is used to evaluate vitamin B12 deficiency or malabsorption. During the test, a blood sample is taken from the patient and the serum is separated. The serum is then mixed with a fixed amount of radioactive vitamin B12. After incubation, the mixture is passed through a column that contains a resin that binds to the transcobalamin-vitamin B12 complex. Any unbound radioactive vitamin B12 will pass through the column and can be measured. The amount of radioactive vitamin B12 that remains bound to transcobalamin is then quantified. A low vitamin B12 binding capacity may indicate a deficiency in transcobalamin or a decreased ability of transcobalamin to bind with vitamin B12. This can be seen in conditions such as pernicious anemia, which is characterized by impaired absorption of vitamin B12 due to the lack of intrinsic factor, a protein necessary for vitamin B12 absorption. It is important to note that this test is not commonly used in clinical practice anymore. Instead, other tests such as serum vitamin B12 levels and methylmalonic acid levels are typically used to diagnose vitamin B12 deficiency. |
