Urea Cycle Disorder Panel in UAE | 1500 AED | DNA Labs UAE Certified

Executive Summary & Core Metrics

Clinical Commitment & Diagnostic Assurance

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection for both urine and plasma samples, ensuring sample integrity at every stage — available daily from 8 AM to 11 PM.
Clinical Guidance: Telephonic Post-Test Clinical Interpretation with a metabolic specialist, directly supporting your physician’s decision-making.
Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731 — confirm coverage before collection.

Test Overview & Methodology

The Urea Cycle Disorder Panel is a specialized metabolic test that quantitatively profiles amino acids and related metabolites in urine and plasma to diagnose inborn errors of the urea cycle. Employing dual-matrix LC-MS/MS and GC/MS, it delivers precise, actionable results within 5 working days for conditions such as citrullinemia, argininosuccinic aciduria, and arginase deficiency. The combined analysis of plasma amino acids and urinary orotic acid provides comprehensive metabolic coverage, enabling early intervention and tailored dietary management.

Feature	Our Test (Urea Cycle Disorder Panel)	Closest Alternative (Standard Amino Acid Panel)
Sample Matrix	Urine + Plasma (dual-matrix) — mandatory cold-chain handling	Plasma or urine only; often single matrix
Methodology	LC-MS/MS + GC/MS (tandem mass spectrometry cross-validated)	HPLC or basic amino acid analyser
Turnaround Time	Report in 5 working days	7–10 working days
Diagnostic Yield	Covers all urea cycle intermediates (orotic acid, citrulline, argininosuccinate, etc.)	Limited to plasma amino acids; may miss orotic aciduria

Physician Insight & Safety Protocols

“As a Consultant Medical Genetics, I emphasize that laboratory findings must be correlated with clinical symptoms and genetic consultation. This panel is a powerful first-line screening tool for urea cycle disorders, but definitive diagnosis often requires confirmatory enzyme assay or molecular genetic testing. I urge families to consult their pediatrician or metabolic specialist immediately if ammonia levels are elevated, while maintaining prescribed medications and dietary restrictions.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Medication Advisory & Pre-Test Precautions

Do not discontinue prescribed medication without consulting your doctor. Certain medications (e.g., valproic acid, sodium benzoate, or corticosteroids) may interfere with test interpretation; always provide a complete drug history at the time of sample collection.

Exclusion Criteria & Emergency Red Flags

Exclusion: Unable to provide both urine and plasma samples; active hemolysis in plasma tube; missing clinical and drug history documentation.
ER Red Flags: If the patient experiences severe vomiting, lethargy, seizures, or respiratory distress, seek immediate emergency care — these symptoms may signal a hyperammonemic crisis. This test is not a substitute for acute medical evaluation.

Patient FAQ & Clinical Guidance

1. What conditions does the Urea Cycle Disorder Panel detect?

This panel accurately detects urea cycle disorders including citrullinemia (types I and II), argininosuccinic aciduria, arginase deficiency, and ornithine transcarbamylase deficiency using dual-matrix metabolic profiling of plasma amino acids and urinary orotic acid.

2. How is the sample collected for this test?

A certified phlebotomist collects a heparinized plasma sample (green-top tube, 2 mL) and a sterile random urine specimen (10 mL) via VIP Mobile Phlebotomy with temperature-controlled cold-chain transport. Both samples are collected during a single home visit scheduled between 8 AM and 11 PM.

3. Why is both urine and plasma needed for diagnosis?

Urine and plasma provide complementary metabolic profiles: plasma amino acids reveal systemic elevations of key intermediates such as citrulline and arginine, while urinary orotic acid serves as a sensitive marker for ornithine transcarbamylase deficiency. Together, they enable precise localization of the enzymatic defect in the urea cycle.

4. How long does it take to receive results, and who interprets them?

Results are available within 5 working days. A detailed interpretive report is issued, and a telephonic consultation with our metabolic specialist is provided to support your physician’s clinical decision-making.

UAE Regulatory & Data Privacy Adherence

Comprehensive Legal Compliance Framework

All diagnostic services provided by DNA Labs UAE fully comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) ensuring secure handling of genetic and metabolic patient data, Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields governing electronic health records and telemedicine, and Federal Decree-Law No. 4 of 2016 on Medical Liability governing clinical testing safety and informed patient consent. Our laboratory is ISO 9001:2015 accredited (Cert: INT/EGQ/2509DA/3139) and holds DHA Facility License No. 1143. All genetic and metabolic information is stored encrypted and used solely for diagnostic purposes with explicit patient consent.

Clinical & Logistical Metadata

Test Name	Urea Cycle Disorder Panel (Plasma & Urine)
Price (AED)	1,500 AED
Turnaround Time	5 working days
Sample Type / Matrix	Urine (random, sterile, 10 mL) + Plasma (sodium heparin, green-top, 2 mL) — dual matrix, cold-chain required
Methodology Used	LC-MS/MS (plasma amino acids) + GC/MS (urinary orotic acid and organic acids) — tandem cross-validated
ICD-10-CM Code	E72.2 (Urea cycle disorders)
LOINC Code	34531-1 (Amino acids panel [Moles/volume] — Plasma)
DHA Facility License & Laboratory Address	License No. 1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE \| DNA Labs UAE

دعم ثنائي اللغة متاح

التحقق من التغطية التأمينية

Check Insurance Coverage Instantly

Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.

توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.

✅ DHA Certified ✅ ISO 15189 ✅ HIPAA Compliant

💬 التحقق عبر الواتساب Verify via WhatsApp 📞 Call Team

Available in Arabic, English, Hindi & Urdu

🏅

ISMS 27001:2022

📋

ISO Accredited

🔒

HIPAA

All reports reviewed by DHA-Certified physicians