Test Price
170 AED✅ Home Collection Available
Beta-2-Microglobulin (B2M), 24-Hour Urine Test in Dubai | 170 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via Chemiluminescent Immunoassay (CLIA).
- Premium Logistics: Hospital-Grade Home Collection available via ISO-certified Temperature-Controlled Cold-Chain and VIP Mobile Phlebotomy.
- Clinical Guidance: Complimentary telephone-based post-test result interpretation by a DHA-licensed specialist.
- Insurance & Billing: Direct billing verification and pre-authorization assistance available via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
Beta-2-Microglobulin (B2M) is a low-molecular-weight protein freely filtered by the glomeruli and almost completely reabsorbed and catabolized by the proximal tubules. Elevated urinary B2M is a sensitive, specific biomarker for proximal tubular dysfunction and serves as a critical prognostic and monitoring tool for lymphoproliferative disorders, particularly multiple myeloma, as well as HIV-associated nephropathy and heavy metal nephrotoxicity. This test utilizes advanced Chemiluminescent Immunoassay (CLIA) technology to deliver superior analytical sensitivity and specificity compared to traditional immunonephelometry.
| Feature | DNA Labs UAE CLIA Platform | Standard Immunonephelometry |
|---|---|---|
| Analytical Sensitivity | 99.9% (Clinical & Analytical) | 95–98% (Susceptible to turbidity) |
| Methodology | Chemiluminescent Immunoassay (CLIA) — High specificity, broad dynamic range, minimal matrix interference | Immunonephelometry — Prone to antigen excess and chylomicron interference |
| Turnaround Time | Same-day reporting (received before 12 PM) | Batch analysis; 2–3 working days |
Physician Insight & Safety Protocols
“As a DHA-licensed diagnostic specialist, I emphasize that an elevated urinary beta-2-microglobulin must always be interpreted alongside serum B2M, estimated glomerular filtration rate (eGFR), and the full clinical hematology profile. A single abnormal value is never diagnostic for multiple myeloma without confirmatory serum protein electrophoresis (SPEP), immunofixation, and bone marrow biopsy. This marker is, however, invaluable for monitoring therapeutic response and detecting early tubular injury from nephrotoxic agents. Always consult your treating physician before making any changes to your prescribed therapy.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology | DHA Registration ID: 61713011
Pre-Test Advisory & Collection Protocol
No special patient preparation is required. The 24-hour urine collection must be complete and meticulously timed. Patients will be provided with a sterile, preservative-free, 3-liter screw-capped container. The collection begins by discarding the first morning void, then collecting all urine output for the next 24 hours, including the first void of the following morning. The container must be refrigerated or maintained on ice during the entire collection period. VIP Mobile Phlebotomy couriers ensure a direct cold-chain transfer to our CAP-accredited laboratory upon collection completion.
Exclusion Criteria & Critical Red Flags
- Incomplete Collection: A 24-hour urine creatinine measurement must validate collection completeness. Collections outside the expected creatinine range will be flagged and may require recollection.
- Contraindications: Active urinary tract infection (UTI), febrile illness, or gross hematuria — defer testing until clinical resolution.
- Medication Warning: Do not discontinue or alter prescribed nephrotoxic or chemotherapeutic agents without explicit instruction from your treating physician.
- Emergency Red Flags: Sudden onset of flank pain, oliguria, anuria, fever, or visible blood in the urine mid-collection. Stop the collection, contact your physician, or proceed to the nearest emergency department.
- Pediatric Consent: For patients under 18 years of age, informed guardian consent is mandatory prior to sample collection and processing.
Patient FAQ & Clinical Guidance
1. What specific condition does an elevated urinary B2M indicate?
Elevated urinary B2M primarily indicates impaired proximal tubular reabsorption. Clinically, this is seen in tubulointerstitial nephritis, acute tubular necrosis, heavy metal poisoning (cadmium, lead, mercury), and most critically, in B-cell lymphoproliferative malignancies such as multiple myeloma and Waldenström macroglobulinemia. It is not a standalone diagnostic test but a highly sensitive biomarker for renal tubular integrity and tumor burden monitoring.
2. What are the logistical steps for providing a 24-hour urine sample?
Upon booking, our logistics team delivers a standardized collection kit to your home or the nearest DNA Labs UAE patient service center. The protocol is: discard the first morning void, note the exact time, then collect every single urination into the provided container over the next 24 hours. The first void of the next morning is the final collection component. The container must be kept refrigerated at 2-8°C throughout. Our VIP Mobile Phlebotomy team retrieves the sealed, labeled container and transports it under strict temperature-controlled conditions to our laboratory for processing.
3. How are my data and sample privacy protected under UAE law?
DNA Labs UAE operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 on Healthcare ICT. Your health data is encrypted, access-controlled, and processed within our secure electronic medical records (EMR) system. Sample handling is tracked via a chain-of-custody barcode system. Your explicit consent is mandatory prior to any testing, and results are shared only with you and your designated referring physician.
UAE Regulatory & Data Privacy Adherence
Comprehensive Legal & Accreditation Framework
This diagnostic service is provided in strict adherence to the UAE healthcare regulatory ecosystem:
- Data Protection: Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Health Data Governance: Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology (ICT) in Health Fields.
- Clinical Safety & Liability: Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Facility License: DHA Facility License Number 1143 issued to Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
- Quality Management: ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
- Corporate Entity: DNA Labs UAE.
Clinical & Logistical Metadata
| Test Name | Beta-2-Microglobulin (B2M), 24-Hour Urine |
| Price (AED) | 170.00 AED |
| Turnaround Time | Same day (reported within 24 hours of sample receipt) |
| Sample Type / Matrix | 24-Hour Urine Collection (Strictly refrigerated, preservative-free) |
| Methodology Used | Chemiluminescent Immunoassay (CLIA) on fully automated high-throughput platform |
| ICD-10-CM Code | R80.1 (Proteinuria, unspecified), E88.09 (Other disorders of plasma-protein metabolism), C90.00 (Multiple myeloma not having achieved remission) |
| LOINC Code | 1518-5 (Beta-2-Microglobulin [Mass/volume] in Urine collected 24h) |
| DHA Facility License & Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Entity: DNA Labs UAE |
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