Test Price
900 AED✅ Home Collection Available
Sirolimus (Rapamycin) Therapeutic Drug Monitoring Test in UAE | 900 AED | DHA-Regulated
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) — the gold standard for immunosuppressant quantification.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM–11 PM; same-day reporting when sample arrives by 5 PM.
- Clinical Guidance: Complimentary telephonic post-test interpretation delivered by a licensed general practitioner to facilitate timely dose discussions with your transplant team.
- Insurance & Billing: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The Sirolimus (Rapamycin) blood test quantitatively measures immunosuppressant drug levels using liquid chromatography-tandem mass spectrometry (LC-MS/MS) to ensure therapeutic efficacy and avoid toxicity in solid organ transplant recipients. This DHA-regulated monitoring assay is essential for personalized dose adjustment in kidney, liver, and other transplant patients across the UAE. Trough concentration must be drawn immediately before the next scheduled dose to capture the accurate 12-hour steady-state level.
| Feature | Our Test – LC-MS/MS | Standard Immunoassay Alternative |
|---|---|---|
| Precision | 99.9% diagnostic sensitivity, high specificity for sirolimus | Cross-reactivity risk, lower accuracy |
| Methodology | Liquid Chromatography-Tandem Mass Spectrometry (Gold Standard) | Homogeneous enzyme immunoassay (CEIA/FPIA) |
| Turnaround Time | Same-day reporting if sample arrives by 5 PM | 24–48 hours typical |
Physician Insight & Safety Protocols
“As a general practitioner working with transplant recipients across the UAE, I see how critical accurate trough monitoring is for long-term graft survival. This LC-MS/MS assay delivers the reliable, reproducible concentration data your transplant team needs to tailor sirolimus dosing precisely. Always review your result with your managing specialist before any dose change; the numeric value alone never tells the full clinical story.”
— Dr. Ajay Singh, General Practitioner, DHA Registration ID: 36234132
Medication Advisory – Do Not Self-Adjust
Never discontinue, skip, or modify your prescribed immunosuppressant dose without explicit verbal or written instruction from your transplant physician. Abrupt changes in sirolimus levels can precipitate acute rejection or expose you to life-threatening toxicity. This blood test is a monitoring aid, not a treatment directive.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion criteria: Known hypersensitivity to sirolimus or rapamycin derivatives; pregnant or breastfeeding individuals unless explicitly directed by the transplant team. This assay is not intended for substance abuse screening or non-medicinal rapamycin use.
- Emergency red flags: Seek immediate emergency care if you develop fever with chills, graft-site tenderness or swelling, sudden reduction in urine output, unexplained bruising or bleeding, persistent vomiting, severe headache, or vision disturbances — regardless of your measured blood level.
Patient FAQ & Clinical Guidance
1. Why do I need a sirolimus blood test after my transplant?
Sirolimus trough monitoring prevents organ rejection and reduces toxicity by enabling precise dose adjustments. Keeping your level within the narrow therapeutic window protects kidney function, supports graft survival, and minimizes adverse effects such as hyperlipidemia or thrombocytopenia.
2. When exactly should I collect the blood sample for this test?
The sample must be drawn immediately before your next scheduled dose — ideally within 30 minutes prior — to capture the accurate 12-hour trough concentration. Please bring your EDTA blood collection tube and record the date, time, and amount of your last two doses for the laboratory.
3. How fast will I receive my sirolimus level results?
Sirolimus levels are reported the same calendar day when the sample reaches our laboratory by 5 PM, enabling prompt clinical decision-making. You will also receive a telephonic summary from our clinical team to help you relay the information to your transplant coordinator efficiently.
4. Can I eat or drink before the blood draw?
Fasting is not required for sirolimus trough measurement, but you should maintain your usual medication schedule and avoid taking your morning dose until after the blood draw. A light meal will not interfere with the LC-MS/MS assay.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Governance: All patient data is encrypted and processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. This laboratory service is licensed and regulated by the Dubai Health Authority (DHA) under facility license number 1143.
ISO 9001:2015 Certification: Certificate No. INT/EGQ/2509DA/3139, ensuring international quality management standards in pre-analytical, analytical, and post-analytical phases.
Clinical & Logistical Metadata
| Test Name | Sirolimus (Rapamycin) Trough Level, Whole Blood |
| Price (AED) | 900 AED |
| Turnaround Time | Same-day reporting when sample arrives by 5 PM |
| Sample Type / Matrix | Whole Blood (EDTA) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM–11 PM |
| Methodology Used | Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) |
| ICD-10-CM Code | Z51.81 |
| LOINC Code | 3395-0 |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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