Test Price
1,000 AED✅ Home Collection Available
Therapeutic Drug Monitoring: Oxcarbazepine Metabolite (10-OH-Carbazepine) Test in Dubai
Executive Summary & Core Metrics
DHA Clinical Assurance & Core Metrics
100% Diagnostic Accuracy: 99.9% sensitivity via ISO 15189:2022 accredited LC-MS/MS processing. Each specimen is tracked with a cold-chain-verified transport protocol, eliminating pre-analytical errors.
Premium Home Collection: VIP mobile phlebotomy service available 8 AM – 11 PM, 7 days a week. Our DHA-licensed nurses use a validated red-top (no-additive) tube, rejecting any SST gel barrier tube to guarantee metabolite stability.
Post-Test Clinical Guidance: A complimentary 10-minute telephonic interpretation session is included. You will receive a clear report with therapeutic reference ranges tailored to pediatric, adult, and geriatric patients.
Insurance & Billing: Direct billing verification via WhatsApp at +971 54 548 8731. Most UAE insurance networks accepted under Federal Law No. 2 of 2019.
Test Overview & Methodology
The Oxcarbazepine Metabolite (10-hydroxycarbazepine, monohydroxy derivative) test quantifies the pharmacologically active moiety that reflects true drug exposure in epilepsy patients. In the UAE, where genetic diversity (e.g., CYP2C9, UGT variants) influences metabolism, this test avoids misleading parent-drug concentrations and guides precise dose adjustments.
| Feature | Our Test (DHA-Endorsed) | Closest Alternative |
|---|---|---|
| Methodology | LC-MS/MS (tandem mass spectrometry) | HPLC-UV or immunoassay |
| Precision (CV%) | <5% across the therapeutic range | 10–20% variability |
| Turnaround Time | 10 working days (Mon–Sat processing) | 14–21 days (often outsourced) |
| Sample Stability | Validated red-top tube, refrigerated shipping | May accept gel tubes, risking metabolite adsorption |
Physician Insight & Safety Protocols
“As a General Practitioner involved in long-term epilepsy management in Dubai, I emphasize that an isolated metabolite level must be interpreted alongside clinical seizure control, renal function, and any signs of toxicity. This test is a decision-support tool—never a substitute for expert clinical judgment. Share your full medication list, including over-the-counter products and herbal supplements, during pre-test counseling.”
— Dr. Ajay Singh, General Practitioner (DHA Registration ID: 36234132)
Critical Medication Advisory
Critical Medication Advisory
Do not discontinue or modify your prescribed oxcarbazepine dosage before this test without direct instruction from your treating physician. Abrupt withdrawal can precipitate breakthrough seizures.
Safety Exclusion Criteria & Emergency Red Flags
- Sample Rejection Criteria: Use of SST gel-barrier tubes; hemolyzed serum; volume <1 mL; unrefrigerated or delayed shipment beyond 24 hours.
- Patient-Related Exclusion: Known allergy to latex or antiseptic used during venipuncture (alternative collection provided if disclosed).
- Red Flags for Immediate Medical Attention: New-onset skin rash, facial swelling, fever, severe dizziness, or confusion. These may indicate a hypersensitivity syndrome or toxic metabolite accumulation. Visit the nearest emergency department.
Patient FAQ & Clinical Guidance
1. Why must I provide a blood sample just before my next dose?
A trough level (collected immediately before the next scheduled dose) reflects the lowest drug concentration during a dosing interval, directly correlating with therapeutic efficacy and toxicity risk. Our 99.9% sensitive LC-MS/MS assay requires this standardized timing to compare your result against validated reference ranges.
2. Can I take this test if I am on other epilepsy medications?
Yes, the LC-MS/MS method is highly specific for 10-hydroxycarbazepine and does not cross-react with lamotrigine, levetiracetam, or valproate. Always inform our DHA-licensed nurse of your full medication list during home collection to ensure no rare matrix interference.
3. How do I interpret my result if the level is outside the normal range?
The standard therapeutic range for 10-hydroxycarbazepine is 10–35 mg/L, but your target may differ based on age, seizure type, and renal function. A physician-guided interpretation is mandatory; do not self-adjust. Our post-test telephonic consultation will connect you directly with a clinical expert.
4. What is the difference between the Oxcarbazepine parent drug test and this Metabolite test?
Oxcarbazepine is rapidly converted to its active metabolite, 10-hydroxycarbazepine (MHD). The parent drug is often undetectable in steady-state serum. Therefore, measuring the metabolite provides a direct and clinically relevant assessment of therapeutic exposure and correlates better with both efficacy and adverse effects compared to the parent drug assay.
UAE Regulatory & Data Privacy Adherence
Regulatory & Quality Compliance
This service is delivered under DHA Facility License 1143, adhering to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, and Federal Decree-Law No. 4 of 2016 on Medical Liability. Our laboratory processes are ISO 15189:2022 accredited. All data is encrypted and stored within UAE borders.
Clinical & Logistical Metadata
| Test Name | Oxcarbazepine Metabolite (10-OH-Carbazepine) Trough Level |
| Price (AED) | 1,000 AED |
| Turnaround Time | 10 Working Days (Mon–Sat processing) |
| Sample Type / Matrix | Peripheral Blood (Serum/Plasma) – Trough Collection |
| Methodology Used | LC-MS/MS (Tandem Mass Spectrometry) |
| ICD-10-CM Code | R79.8 (Other specified abnormal findings of blood chemistry), G40.909 (Epilepsy, unspecified) |
| LOINC Code | 35368-2 (Oxcarbazepine metabolite [Mass/volume] in Serum or Plasma) |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. Lab: DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians