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Test Price

150,000 AED

✅ Home Collection Available

Targeted Sequencing (Below 50 Kb) in Dubai | 150,000 AED | DHA Licensed

Executive Summary & Core Metrics

Executive Summary: DNA Labs UAE delivers ultra-high fidelity targeted sequencing for genomic regions below 50 kilobases, processed under strict DHA oversight at our Dubai Healthcare City facility. This test achieves 99.9% diagnostic sensitivity via ISO 9001:2015 accredited protocols (Cert: INT/EGQ/2509DA/3139), enabling oncologists and clinical researchers to detect sub-clonal variants with allelic frequencies below 1%.

  • 01. Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
  • 02. Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, available daily from 8 AM to 11 PM.
  • 03. Clinical Guidance: Telephonic post-test result interpretation by a DHA-licensed Consultant Medical Genetics.
  • 04. Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

Targeted Sequencing (Below 50 Kb) is a high-resolution genomic assay that focuses on specific, clinically actionable regions of the genome using extracted DNA. This technique employs hybridization-based capture followed by deep sequencing to identify low-frequency variants critical for precision oncology protocols, minimal residual disease monitoring, and research-grade hypothesis validation. The ultra-deep coverage profile reliably detects sub-clonal mutations that broader panels miss.

Feature DNA Labs UAE Targeted Sequencing Standard NGS Panel
Precision & Depth Ultra-deep coverage for regions <50 Kb; allelic frequency detection at <1%. Moderate coverage across broader gene panels; may miss low-frequency sub-clonal variants.
Methodology Hybridization capture with validated library quantification. Amplicon-based chemistry, subject to PCR bias and allele dropout.
Turnaround Time 10 Weeks (Multi-phasic bioinformatics pipeline with manual curation by PhD researchers). 4–6 Weeks (Automated variant calling with limited manual review).

Physician Insight & Safety Protocols

A Note from Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA: 9294403): “This targeted sequencing assay provides a deep, focused view of specific genomic regions that are most relevant to your clinical presentation. The results must always be interpreted alongside your full medical history, imaging data, and prior laboratory findings. A single genomic snapshot does not define your entire disease trajectory—it is one piece of a larger diagnostic mosaic that requires careful integration by your treating physician.”

Critical Advisory

Medication Guidance

Do not discontinue or modify any prescribed medication, including targeted therapy or immunotherapy, based solely on these genomic findings without explicit consultation with your treating oncologist.

Safety Exclusion Criteria & Emergency Red Flags

  • Exclusion: This test is validated for extracted DNA samples only; hemolyzed or improperly stored whole blood samples will be rejected. Minors require guardian consent in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
  • Emergency Red Flag: The 10-week turnaround time makes this test unsuitable for acute clinical crisis. Seek immediate emergency care for uncontrolled pain, acute neurological changes, or new-onset severe organ dysfunction.
  • Data Privacy: Your genomic data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.

Patient FAQ & Clinical Guidance

1. Why does the Targeted Sequencing (Below 50 Kb) test take 10 weeks to complete?

The extended 10-week turnaround ensures rigorous experimental validation and multi-phasic bioinformatics review for ultra-low variant allelic frequencies. Your extracted DNA undergoes library preparation, hybridization-based enrichment, and deep sequencing, followed by manual curation from our Medical and PhD researchers to filter out sequencing noise and confirm pathogenic variants. This meticulous process is essential for delivering actionable oncologic precision.

2. How does this targeted panel differ from whole exome sequencing?

Unlike broad exome analysis, our sub-50 Kb targeted test provides significantly deeper sequencing coverage over a narrow, clinically relevant genomic region. This ultra-deep approach reliably detects low-frequency sub-clonal mutations in oncogenes that would be missed by the shallower depth of standard whole exome sequencing. It is preferred for tracking minimal residual disease or characterizing a specific known locus.

3. Is home collection available and how is sample stability maintained?

Yes, our VIP mobile phlebotomy service provides a DHA-licensed professional to collect your whole blood sample from your home. The sample is immediately placed in a proprietary preservative tube and transported within a real-time monitored, ISO-certified cold chain (2–8°C) directly to our central lab for DNA extraction. This ensures absolute nucleic acid integrity and prevents pre-analytical degradation that can cause false negatives.

UAE Regulatory & Data Privacy Adherence

Regulatory Compliance Framework

DNA Labs UAE operates under DHA Facility License Number 1143 and adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for all patient genomic data. Our data handling protocols also comply with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, ensuring secure storage, encrypted transmission, and restricted access to your genetic information. Clinical consent processes follow Federal Decree-Law No. 4 of 2016 on Medical Liability to guarantee informed patient authorization before any sample processing begins.

Clinical & Logistical Metadata

Test Name Targeted Sequencing (Below 50 Kb)
Price (AED) 150,000 AED
Turnaround Time 10 Weeks
Sample Type / Matrix Extracted DNA (Whole Blood) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM
Methodology Used Targeted Sequencing via Hybridization Capture
ICD-10-CM Code Z13.89
LOINC Code 82323-6
DHA Facility License & Laboratory Address License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE

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