Test Price
700 AED✅ Home Collection Available
Treponema pallidum (Syphilis) RNA Detection Qualitative Test in UAE – 700 AED | DHA Licensed
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited processing. The RT‑qPCR assay directly detects Treponema pallidum RNA from blood, urogenital swab, rectal swab, or urine specimens, confirming active syphilis infection with 95% sensitivity during the primary chancre stage – closing the critical early diagnostic gap 7–10 days before seroconversion.
Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily from 8 AM to 11 PM. Samples are transported under strict chain‑of‑custody protocols to our DHA‑licensed laboratory in Dubai Healthcare City.
Clinical Guidance: Complimentary telephonic post‑test clinical guidance with result interpretation by a DHA‑licensed general practitioner.
Insurance Support: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This real‑time reverse transcription polymerase chain reaction (RT‑qPCR) test targets the 16S ribosomal RNA of Treponema pallidum, providing direct nucleic acid detection of active bacterial burden. Unlike standard serology which relies on indirect antibody measurement, this molecular method identifies infection before seroconversion and remains positive throughout treatment monitoring. The assay is validated for whole blood (EDTA), serum, urethral swab, endocervical swab, rectal swab, and first‑void urine matrices.
| Feature | RNA RT‑qPCR (This Test) | Standard Serology (RPR/TPPA) |
|---|---|---|
| Diagnostic Sensitivity (Primary Stage) | 95% – detects active infection at chancre stage | 50–80% – may miss early cases before seroconversion |
| Detection Window | 7–10 days before seroconversion; confirms active bacterial presence | Requires 2–4 weeks for antibody development; potential false negatives in recent exposure |
| Method Principle | Nucleic acid amplification (RT‑qPCR) targeting 16S rRNA | Antibody detection – nontreponemal (RPR) + treponemal (TPPA) combined |
| Result Turnaround | Phone result at 36 h; email report at 48 h (4th working day) | 2–5 days; may require paired titre measurement for interpretation |
Physician Insight & Safety Protocols
“Testing for syphilis can raise complex clinical and emotional considerations. An RNA‑positive signal confirms active bacterial replication and warrants prompt specialist assessment for antibiotic therapy under DHA guidelines. I support every patient through confidential result correlation and personalised next‑steps counselling, always safeguarding privacy and well‑being.”
— Dr. Ajay Singh, General Practitioner, DHA Registration ID: 36234132
Therapeutic Advisory
⚠️ Medication Advisory
Do not discontinue, alter, or self‑adjust any prescribed antibiotic or antiviral medication without consulting your treating physician. A positive RNA result requires DHA‑recommended treatment with penicillin G under specialist supervision – never self‑medicate or delay care.
Safety Exclusion Criteria & Emergency Red Flags
- Individuals under 18 years without a legal guardian’s written informed consent (Federal Decree‑Law No. 4 of 2016 on Medical Liability).
- Severe bleeding disorders or current anticoagulant therapy that may complicate swab collection (urethral, endocervical, or rectal).
- Known hypersensitivity or anaphylaxis to topical anaesthetics (if lignocaine gel is used for swab comfort).
- Active heavy genital bleeding, extensive open wounds, or active herpetic lesions at the intended swab collection site.
- Seek immediate emergency care if you experience: sudden severe headache, vision changes, hearing loss, chest pain, or focal neurological deficits – these may signal neurosyphilis complications requiring urgent hospital assessment.
Patient FAQ & Clinical Guidance
1. How accurate is the Treponema pallidum RNA PCR compared to standard blood tests for syphilis?
The RNA RT‑qPCR test achieves 95% sensitivity during the primary chancre stage, detecting infection 7–10 days before seroconversion – a period when standard serology (RPR/TPPA) may still be negative. Because the assay directly amplifies bacterial RNA rather than measuring host antibodies, it confirms active bacterial replication and eliminates the false‑negative window of early infection. Our ISO‑9001:2015 accredited laboratory applies confirmatory quality controls, and every result is reviewed by a DHA‑licensed general practitioner before release.
2. Can I arrange a home collection for syphilis testing without a doctor referral in the UAE?
Yes – you may book our DHA‑licensed home collection service directly without a prior physician referral for asymptomatic screening, post‑exposure assessment, or routine sexual health checks. A trained male or female phlebotomist will arrive at your residence between 8 AM and 11 PM with a temperature‑controlled transport system and collect the required specimen (blood, urethral or endocervical swab, rectal swab, or urine) in complete privacy. Pre‑test telephonic counselling is included in the service, and your sample is processed under Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL).
3. What steps should I follow if my RNA result is positive for syphilis?
A positive RNA result confirms active Treponema pallidum infection and requires prompt DHA‑recommended treatment with intramuscular penicillin G under the supervision of an infectious disease or dermatovenereology specialist – do not self‑medicate or postpone care. Our clinical team will arrange a confidential tele‑consultation within hours of result release to explain the finding, coordinate a treatment plan, and notify sexual partners for testing (with your consent). Follow‑up RNA testing at three months post‑treatment is advised to confirm microbiological clearance, and paired serology may be used for long‑term surveillance.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License Number 1143 and complies with all applicable UAE federal health data protection and medical liability statutes. Your personal health information is processed and stored in accordance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL), ensuring lawful collection, purpose limitation, and your right to access or request deletion of your data. All electronic health records and diagnostic results are transmitted using encrypted channels as mandated by Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical consent, sample collection, and laboratory procedures adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability, guaranteeing patient safety and professional accountability throughout the testing pathway.
Clinical & Logistical Metadata
| Test Name | Treponema pallidum (Syphilis) RNA Detection Qualitative Test (RT‑qPCR) |
| Price (AED) | 700 AED |
| Turnaround Time | Phone result at 36 hours; email report at 48 hours (4th working day) |
| Sample Type / Matrix | Whole blood (EDTA), serum, urethral swab, endocervical swab, rectal swab, first‑void urine |
| Methodology Used | Real‑time reverse transcription polymerase chain reaction (RT‑qPCR) targeting 16S ribosomal RNA |
| ICD-10-CM Code | A51.9 (Early syphilis, unspecified) – Diagnostic confirmation of active infection; Z11.3 (Encounter for screening for infections with a predominantly sexual mode of transmission) – Asymptomatic screening |
| LOINC Code | 17784-8 – Treponema pallidum DNA [Presence] in Specimen by NAA with probe detection (applicable to RNA qualitative detection via nucleic acid amplification) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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