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Test Price

9,000 AED

✅ Home Collection Available

PacBio Sequel II 1GB Long-Read Sequencing (HiFi) in UAE | 9,000 AED | DHA Licensed

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited SMRT sequencing with HiFi reads.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM, or direct submission of high-quality extracted DNA.
  • Clinical Guidance: Complimentary telephonic post-test clinical interpretation session by a DHA-licensed genomics expert.
  • Insurance & Billing: Direct Billing Verification via WhatsApp at +971 54 548 8731.
  • Facility & License: DNA Labs UAE – Dubai Healthcare City, DHA License No. 1143.

Test Overview & Methodology

The PacBio Sequel II 1GB long-read sequencing service provides ultra-high molecular weight genomic analysis with HiFi reads, ideal for structural variant detection, phasing, and de novo assembly—exceeding the resolution of short-read platforms. The technology utilizes Single Molecule Real-Time (SMRT) circular consensus sequencing to achieve Q30 quality and >99% consensus accuracy with haplotype-resolved data.

Feature Our Test (PacBio Sequel II HiFi) Closest Alternative (Short-Read NGS)
Precision Q30 quality, >99% consensus accuracy, Haplotype-resolved Q30 for SNVs, but structural rearrangements often missed; no phasing
Method Single Molecule Real-Time (SMRT) CCS, 1GB throughput Illumina sequencing by synthesis, 150 bp reads
TAT & Price 4 weeks, 9,000 AED (all inclusive) 2-3 weeks, ~3,500 AED (limited detection)

Physician Insight & Safety Protocols

Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA Registration ID: 9294403) notes: “PacBio HiFi long-read sequencing excels at resolving structural variants, repeat expansions, and pseudo-gene regions that remain invisible to short-read panels. However, every variant must be interpreted within the patient’s clinical context and family pedigree. This test is a comprehensive genomic tool; final clinical decisions require multidisciplinary evaluation.”

Medication Warning

Do not discontinue any prescribed medication without explicit consultation with your referring physician. Sequencing results do not constitute acute treatment advice.

Patient Safety – Exclusion Criteria & Red Flags

  • Severe hemophilia or active bleeding disorder uncontrolled – venipuncture risk; alternative sampling route required.
  • Inadequate extracted DNA: sample must be high molecular weight, OD 260/280 ratio 1.8‑2.0, concentration ≥ 50 ng/µL, shipped on dry ice.
  • For minors (<18 years): consent must comply with Federal Decree-Law No. 4 of 2016 on Medical Liability – parental/legal guardian signature mandatory.
  • ER Red Flags: If you experience chest pain, sudden neurological deficit, or severe allergic reaction, proceed to the nearest emergency department; do not wait for test instructions.

Patient FAQ & Clinical Guidance

1. What can this long-read sequencing detect that standard panels cannot?

PacBio HiFi long-read sequencing can identify large structural variants, transposon insertions, segmental duplications, and provide gapless assemblies—alterations invisible to exome or short-read genome tests.

2. How should I prepare my sample, and can I submit extracted DNA?

You may provide 2‑5 mL of whole blood in EDTA (collected by our cold-chain mobile team) or ship high-quality extracted DNA (>50 ng/μL, OD 260/280 ratio 1.8‑2.0) on dry ice.

3. When will I receive my results, and how will they be explained?

The report is delivered within 4 weeks via encrypted email, followed by a scheduled 20-minute teleconsultation with our genomic clinical expert to interpret key findings and their implications.

Clinical & Logistical Metadata

Parameter Value
Test Name PacBio Sequel II 1GB Long-Read Sequencing (HiFi)
Price (AED) 9,000 AED (all inclusive)
Turnaround Time 4 weeks
Sample Type / Matrix Whole blood (2-5 mL EDTA) or high-quality extracted DNA (≥50 ng/µL, OD 260/280 1.8-2.0)
Methodology Used Single Molecule Real-Time (SMRT) Circular Consensus Sequencing with HiFi reads
ICD-10-CM Code Z13.89 (Encounter for screening for other genetic and chromosomal anomalies)
LOINC Code 81248-8 (Whole genome sequencing)
DHA Facility License & Address DHA License No. 1143 · DNA Labs UAE – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

UAE Regulatory & Data Privacy Adherence

Your personal health data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All home collections are performed under ISO 9001:2015 standards. For appointments: WhatsApp +971 54 548 8731.

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