Test Price
2,800 AED✅ Home Collection Available
C4BPA Gene Recurrent Pregnancy Loss Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
This advanced next‑generation sequencing (NGS) test targets the C4BPA gene, which plays a critical role in coagulation and immune regulation during pregnancy. It offers 99.9% analytical sensitivity and specificity for detecting pathogenic variants linked to recurrent pregnancy loss. The service includes VIP mobile phlebotomy and temperature‑controlled cold‑chain home collection (daily 8 AM – 11 PM), plus complimentary post‑test genetic counselling by a DHA‑licensed consultant. Direct billing verification is available via WhatsApp.
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited processing.
- Premium Logistics: VIP mobile phlebotomy and temperature‑controlled cold‑chain home collection (8 AM – 11 PM).
- Clinical Guidance: Complimentary telephonic post‑test interpretation by a DHA‑licensed genetic counsellor.
- Insurance: Direct billing verification via +971 54 548 8731.
Test Overview & Methodology
The C4BPA gene test employs next‑generation sequencing (NGS) to analyse the complete coding region and splice‑site junctions of the C4BPA gene. This approach identifies single‑nucleotide variants, small insertions/deletions, and copy‑number alterations that may increase the risk of recurrent miscarriage. The test is recommended for women who have experienced two or more unexplained pregnancy losses and wish to explore genetic causes that may inform reproductive planning, immunotherapy, or preimplantation genetic testing.
| Parameter | Our C4BPA NGS Test | Closest Alternative |
|---|---|---|
| Precision | 99.9% analytical sensitivity & specificity for C4BPA coding regions | Standard chromosomal microarray – low resolution, not gene‑specific |
| Methodology | NGS with full gene coverage | Sanger sequencing of limited exons |
| Turnaround Time | 3–4 weeks | 6–8 weeks |
| Sample Types | Whole blood, extracted DNA, or one drop blood on FTA card | Whole blood only |
| Regulatory Compliance | DHA/MOHAP, UAE PDPL (Federal Decree‑Law No. 45 of 2021), Federal Law No. 2 of 2019 | Varies; may lack UAE‑specific data sovereignty |
Physician Insight & Safety Protocols
“Recurrent pregnancy loss is a deeply personal journey. The C4BPA gene test provides a precise molecular lens into the genetic factors contributing to miscarriage, but it must be interpreted alongside a comprehensive clinical and familial assessment. I encourage patients to view these results as a starting point for a tailored, multidisciplinary care plan rather than a definitive answer. Always consult your geneticist and obstetrician before making any treatment decisions.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Reg. No. 9294403
Medication Advisory
⚠️ Medication Advisory
Do not discontinue any prescribed medications—including anticoagulants or immunomodulators—without explicit guidance from your treating physician. Genetic test results alone do not warrant changes to your current obstetric management plan.
Safety Exclusion Criteria & Red Flags
Exclusion Criteria & ER Red Flags
- Exclusion Criteria: Active systemic infection, known bleeding diathesis, inability to provide informed consent, or current anticoagulant therapy that cannot be safely paused for collection.
- Post‑collection Red Flags: Persistent bleeding at venipuncture site, signs of local infection (redness, swelling, pus), or fever >38°C within 24 hours post‑draw. Seek immediate emergency care.
- Pregnancy Note: Home collection during active pregnancy requires clearance from your obstetrician. Report any cramping or leakage immediately.
Patient FAQ & Clinical Guidance
1. What is the C4BPA gene test and why is it recommended for recurrent pregnancy loss?
This NGS test identifies mutations in the C4BPA gene, which regulates immune and coagulation pathways essential for placental health. It is recommended for women with unexplained recurrent miscarriages to uncover genetic predispositions that can guide personalised immunotherapy or preimplantation genetic testing.
2. How is the test performed and what sample is required?
A trained phlebotomist collects a small venous blood sample (or a drop on an FTA card) at your home using cold‑chain protocols. The sample is then securely transported to our ISO‑accredited lab for NGS analysis. No clinic visit is required.
3. What do my results mean and how soon will I receive them?
Results are delivered within 3–4 weeks. A positive result indicates a pathogenic C4BPA variant, which your genetic counsellor and obstetrician will use to tailor your reproductive plan—including potential immunotherapy or preimplantation genetic testing. A negative result does not rule out other genetic or non‑genetic causes.
UAE Regulatory & Data Privacy Adherence
✅ UAE Healthcare Law Compliance
- Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL): All patient data is encrypted, stored on UAE‑based servers, and processed with explicit consent.
- Federal Law No. 2 of 2019 Concerning Use of ICT in Health Fields: Ensures secure electronic health data exchange and telemedicine compliance.
- Federal Decree‑Law No. 4 of 2016 on Medical Liability: Governs clinical safety, patient consent, and professional accountability.
- ISO 9001:2015 Certified Facility (Cert: INT/EGQ/2509DA/3139), License No. 9834453.
Clinical & Logistical Metadata
| Test Name | C4BPA Gene Sequencing (NGS) for Recurrent Pregnancy Loss |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or FTA card blood spot |
| Methodology Used | Next‑Generation Sequencing (NGS) – full gene coverage |
| ICD-10-CM Code | O26.86 (Recurrent pregnancy loss), Z31.5 (Genetic counselling) |
| LOINC Code | 94222-9 (DNA mutations identified in gene(s) by NGS) |
| DHA Facility License & Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (DNA Labs UAE) |
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