Also known as: Gordon Syndrome Genetic Test
Test Price
2,800 AEDโ Home Collection Available
๐ Results in 3 to 4 Weeks
WNK4 Gene Pseudohypoaldosteronism Type 2B Genetic Test - 2800 AED
Executive Summary & Core Metrics
- โ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing.
- โ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- โ Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by a DHA-licensed specialist.
- โ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The WNK4 Genetic Test precisely identifies mutations responsible for pseudohypoaldosteronism type 2B (Gordon syndrome), a rare hypertensive disorder of renal electrolyte handling. This advanced sequencing panel empowers nephrologists, endocrinologists, and general physicians to confirm the diagnosis and tailor blood pressure management.
| Feature | Our WNK4 NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | 99.9% sensitivity for known & novel WNK4 mutations | ~95% for targeted regions; may miss large deletions |
| Methodology | Next Generation Sequencing (NGS) โ comprehensive gene coverage | Sanger sequencing โ amplicon-based, limited to exons |
| Turnaround Time | 3 to 4 Weeks | 6 to 8 Weeks |
Physician Insight & Safety Protocols
โAs a clinician, I understand the anxiety that accompanies genetic testing for rare conditions like pseudohypoaldosteronism type 2B. This high-fidelity WNK4 test provides critical molecular confirmation, but it must be integrated with your complete clinical picture, family history, and biochemical workup. No single laboratory report can replace an in-depth consultation.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Medication Precautions
Do not discontinue any prescribed antihypertensive or other medication without consulting your treating physician. Sudden withdrawal can provoke dangerous blood pressure spikes or electrolyte disturbances.
Emergency Red Flags & Exclusion Criteria
- Exclusion Criteria: Pregnancy (genetic counseling required before testing); recent blood transfusion (within 3 months) may interfere with germline DNA purity. Active severe infection requiring urgent management should be prioritized.
- Emergency Red Flags โ Seek immediate care if you experience: severe headache with confusion, crushing chest pain or palpitations, muscle weakness or paralysis, sudden abdominal pain with vomiting. These may signal a hypertensive crisis or life-threatening hyperkalemia โ call 998 for ambulance or go to the nearest emergency department.
Patient FAQ & Clinical Guidance
1. What is the WNK4 gene test for pseudohypoaldosteronism type 2B, and why is it ordered?
The WNK4 NGS test detects genetic mutations causing Gordon syndrome with 99.9% sensitivity, aiding precise diagnosis and personalized hypertension management. It is ordered when clinical signs of hyperkalemia and hypertension suggest a hereditary salt-wasting disorder.
2. How long does it take to receive my WNK4 DNA test results?
Our ISO-accredited lab delivers your complete WNK4 NGS report within 3 to 4 weeks, ensuring rapid clinical decision-making without compromising analytical accuracy. This timeframe includes DNA extraction, library preparation, sequencing, bioinformatics analysis, and expert interpretation.
3. Can I arrange a home blood collection for this genetic test in the UAE?
Yes, we offer VIP home phlebotomy service with ISO-certified cold chain transport, minimizing patient inconvenience and ensuring sample integrity. Our DHA-compliant mobile team covers all emirates, including same-day appointments for urgent clinical needs.
UAE Regulatory & Data Privacy Adherence
DHA-CERTIFIED LAB & LEGAL COMPLIANCE
DNA Labs UAE operates under DHA License No. 1143. All genetic testing and patient data handling comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and safety protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Laboratory accreditation: ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | WNK4 Gene Pseudohypoaldosteronism Type 2B Genetic Test |
| Price (AED) | 2800 |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM) |
| Methodology Used | Next Generation Sequencing (NGS) |
| ICD-10-CM Code | E26.8 |
| LOINC Code | 81247-9 |
| DHA Facility License & Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
Preparation Required
["No specific fasting required", "Do not discontinue prescribed medications unless advised by your physician"]
Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians