Test Price
2,800 AEDโ Home Collection Available
Protein S Antigen Total Test in UAE | Accurate Thrombophilia Screening & Clinical Guidance
Executive Summary & Core Metrics
- Price: 2,800 AED โ Fully inclusive of ISO 15189 accredited processing, clinical oversight, and telephonic result interpretation.
- Turnaround Time: 14โ21 calendar days from sample receipt at the central laboratory.
- Sample Type: Platelet-poor plasma (PPP) โ collected via VIP Mobile Phlebotomy with temperature-controlled cold-chain logistics (available daily 8 AM โ 11 PM).
- Methodology: Fully automated immunoturbidimetry โ 99.9% diagnostic sensitivity verified through internal quality control and external proficiency programs.
- Insurance & Billing: Direct billing verification available via WhatsApp +971 54 548 8731.
Test Overview & Methodology
Protein S Antigen Total quantifies the total circulating concentration of Protein S, a vitamin K-dependent natural anticoagulant. This assay is essential for screening inherited or acquired Protein S deficiency โ a well-established risk factor for venous thromboembolism (VTE). Results guide long-term anticoagulation strategy and inform family cascade screening when hereditary thrombophilia is suspected. The test is performed using fully automated immunoturbidimetry on ISO 15189-accredited analyzers, ensuring high precision and reproducibility across all sample runs.
| Feature | DNA Labs UAE Service | Closest Alternative |
|---|---|---|
| Methodology | ISO 15189 Fully Automated Immunoturbidimetry | Standard ELISA or Manual Immunoturbidimetry |
| Diagnostic Sensitivity | 99.9% | ~95% |
| Turnaround Time | 14โ21 Days | 3โ4 Weeks |
| Sample Stability & Transport | PPP frozen at โ20ยฐC with validated cold-chain courier | Often non-validated ambient transport |
Physician Insight & Safety Protocols
A Note from Dr. Ajay Singh โ General Practitioner, DHA Registration ID: 36234132:
โProtein S antigen levels must always be interpreted within the full clinical picture โ including concurrent anticoagulant use, pregnancy, liver function, and acute inflammatory status. An isolated low result does not confirm deficiency; it warrants a comprehensive hemostasis workup and, when appropriate, genetic counseling. My team ensures every patient receives a clear, evidence-based explanation of their findings and a structured follow-up plan tailored to their individual risk profile.โ
Important Medication Advisory
⚠️ Medication Warning
Do not discontinue or adjust any prescribed anticoagulant therapy (including warfarin, heparin, or direct oral anticoagulants) without explicit instruction from your treating physician. Holding medication can precipitate thromboembolic events. This test is a diagnostic aid, not a substitute for medical advice.
Safety Exclusion Criteria & Emergency Red Flags
⚠️ Exclusion & Urgent Care Indicators
- Exclusion: Active thrombosis or major surgery within the previous 4 weeks. Anticoagulation may be temporarily held only under direct physician order.
- Emergency Red Flags โ Seek Immediate Care: Sudden onset shortness of breath, sharp pleuritic chest pain, unilateral leg swelling with erythema and warmth, or any signs suggestive of pulmonary embolism or deep vein thrombosis.
- Pre-analytical Requirements: Overnight fasting is recommended. Completion of Coagulation Requisition Form (Form 15) and Test Send-Out Consent Form (Form 35) is mandatory. Platelet-poor plasma must be prepared and frozen at โ20ยฐC within 4 hours of collection if transport is delayed.
Patient FAQ & Clinical Guidance
1. What is the Protein S Antigen Total test?
This blood test measures the total concentration of Protein S, a natural anticoagulant protein produced in the liver. It is used to screen for inherited or acquired Protein S deficiency โ a condition that increases the risk of abnormal blood clot formation, particularly in the veins of the legs and lungs.
2. Why has my doctor recommended this test?
Your doctor may recommend this test if you have a personal or family history of unprovoked venous thromboembolism, recurrent miscarriage, or abnormal clotting at a young age. It is also used as part of a thrombophilia panel to evaluate patients before long-term anticoagulation or major surgery.
3. How should I prepare for the sample collection?
An overnight fast (8โ12 hours) is strongly advised to minimize lipemic interference. You must complete the Coagulation Requisition Form (Form 15) and the Test Send-Out Consent Form (Form 35) prior to collection. Please inform the phlebotomist of any anticoagulant medications you are currently taking.
4. What does a low Protein S level mean?
A low total Protein S level may indicate an inherited deficiency (genetic mutation in PROS1 gene), an acquired deficiency due to liver disease, vitamin K deficiency, pregnancy, estrogen therapy, or ongoing anticoagulation with warfarin. A single low result is not diagnostic; repeat testing and functional assays (Protein S activity) are typically required for confirmation.
5. Is home sample collection available for this test?
Yes. Because the sample is peripheral whole blood (plasma), our VIP Mobile Phlebotomy service is available daily from 8 AM to 11 PM. A trained phlebotomist will collect the sample at your home under strict temperature-controlled cold-chain conditions to ensure plasma stability during transport to our ISO 15189 accredited laboratory.
UAE Regulatory & Data Privacy Adherence
✅ Compliant with UAE Health Data Protection Standards
DNA Labs UAE operates under the governance of the Dubai Healthcare City Authority (DHCA) and adheres to all federal data protection and health information privacy laws applicable in the United Arab Emirates.
- Data Privacy: All patient data is processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
- Health Information Security: Electronic health records and laboratory data are safeguarded under Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Medical Liability & Patient Safety: Clinical testing and patient consent procedures follow the standards set by Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring transparent communication and informed consent before any invasive or diagnostic procedure.
Clinical & Logistical Metadata
| Test Name | Protein S Antigen Total |
| Price (AED) | 2,800 AED |
| Turnaround Time | 14โ21 Calendar Days |
| Sample Type / Matrix | Platelet-Poor Plasma (PPP) โ Frozen at โ20ยฐC |
| Methodology Used | Fully Automated Immunoturbidimetry (ISO 15189 Accredited) |
| ICD-10-CM Code | D68.59 (Other primary thrombophilia โ Protein S deficiency) |
| LOINC Code | 12072-5 (Protein S Ag [Mass/volume] in Platelet poor plasma) |
| DHA Facility License & Address | DHA Facility License No. 1143 โ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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