QF‑PCR Aneuploidy Screening (Rapid Prenatal Test) The UAE Standard for Fetal Chromosome Assessment

Executive Summary & Core Metrics

Test: QF‑PCR Aneuploidy Screening

Target: Trisomies 21, 18, 13, Sex Chromosome Aneuploidies

Methodology: Quantitative Fluorescence PCR with Capillary Electrophoresis

Turnaround Time: 1–2 Working Days

Price: 800 AED

Clinical Guidance: Post‑test genetic counselling is recommended for all patients

Test Overview & Methodology

Quantitative Fluorescence Polymerase Chain Reaction (QF‑PCR) is a rapid molecular technique that analyzes short tandem repeat markers to detect common fetal aneuploidies. It serves as a highly accurate, first‑tier screening tool for Trisomy 21, 18, 13, and sex chromosome anomalies, delivering results within 1–2 days to enable timely clinical decisions while preserving genetic privacy under UAE law.

Feature	Our QF‑PCR (DNA Labs UAE)	Conventional Karyotype
Precision	>99% sensitivity for targeted aneuploidies	5–10% culture failure risk
Methodology	QF‑PCR with automated capillary electrophoresis	G‑banded chromosome analysis, manually interpreted
Speed	1–2 days	10–14 days
Sample Required	Amniotic fluid / CVS / Cord blood	Amniotic fluid / CVS

Physician Insight & Safety Protocols

As a Consultant Medical Genetics specialist, I advise that QF‑PCR screening offers rapid and highly accurate detection of common fetal aneuploidies. However, results must always be interpreted alongside ultrasound findings and maternal history. This test is a powerful screening tool, not a standalone diagnostic verdict. Follow‑up genetic counselling is essential for comprehensive pregnancy management.

– Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403

Consent & Safety Protocols

Informed Consent & Medical Liability

In accordance with Federal Decree‑Law No. 4 of 2016 on Medical Liability, all invasive prenatal procedures require explicit written informed consent. Patients must be counselled on the risks and benefits of amniocentesis or CVS before sample collection.

Exclusion Criteria & Emergency Red Flags

Active uterine infection or untreated maternal bleeding disorders contraindicate invasive sampling.
Seek immediate emergency care if post‑procedure you experience severe abdominal pain, fever, vaginal bleeding, or leakage of amniotic fluid.
QF‑PCR is not validated as a standalone screen for microdeletion syndromes, balanced translocations, or complex structural rearrangements.

Patient FAQ & Clinical Guidance

1. What is QF‑PCR aneuploidy screening?

QF‑PCR is a rapid molecular test that analyzes short tandem repeat markers to detect common fetal chromosomal anomalies, such as Trisomy 21 (Down syndrome), 18 (Edwards syndrome), and 13 (Patau syndrome), providing results within 1–2 days.

2. How is the sample collected for this test?

This is a hospital‑only procedure. A qualified obstetrician collects a sample of amniotic fluid (amniocentesis) or chorionic villi (CVS) under ultrasound guidance to ensure fetal and maternal safety. Mobile home phlebotomy is disabled for this invasive test.

3. When will I receive my test results?

Your QF‑PCR report is typically delivered within 1–2 working days from sample receipt at our ISO 9001:2015 certified laboratory in Dubai Healthcare City.

4. Is my genetic information protected by UAE law?

Yes. DNA Labs UAE strictly adheres to Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 on ICT in Health Fields, ensuring your genetic data is encrypted, securely stored, and never shared without your explicit consent.

UAE Regulatory & Data Privacy Adherence

Your Data, Your Rights

DHA Facility License: 1143
Data Protection: Fully compliant with Federal Decree‑Law No. 45 of 2021 (PDPL).
Health ICT Governance: Adherence to Federal Law No. 2 of 2019 on the Use of Information and Communication Technology in Health Fields.
Medical Liability: Procedures conducted under Federal Decree‑Law No. 4 of 2016.
Certification: ISO 9001:2015 Certified for quality management systems.

Clinical & Logistical Metadata

Test Name	QF‑PCR Aneuploidy Screening (Rapid Prenatal Test)
Price (AED)	800 AED
Turnaround Time	1–2 Working Days
Sample Type / Matrix	Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
Methodology Used	Quantitative Fluorescence PCR (QF‑PCR) with Capillary Electrophoresis
ICD-10-CM Code	O35.1
LOINC Code	73544-6
DHA License & Address	DHA Facility License: 1143 \| Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE \| Corporate Lab: DNA Labs UAE