Test Price
1,800 AEDโ Home Collection Available
๐ Results in 12 Working Days
Prader-Willi Syndrome Methylation-Specific PCR Test in Dubai, UAE
Executive Summary & Core Metrics
- 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing at DNA Labs UAE.
- VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily across all Emirates (8 AM โ 11 PM).
- Telephonic Post-Test Clinical Guidance provided by our Consultant Medical Genetics for result interpretation.
- Direct Billing Verification via WhatsApp: +971 54 548 8731.
Test Overview & Methodology
Prader-Willi Syndrome (PWS) is a complex genetic disorder caused by loss of function of paternal genes in chromosome 15q11-q13. This methylation-specific PCR test detects the abnormal methylation pattern to confirm the diagnosis with high precision. DNA Labs UAE performs this analysis on peripheral whole blood specimens under strict ISO 15189 and DHA quality frameworks.
| Aspect | Methylation-Specific PCR (Our Test) | FISH (Alternative) |
|---|---|---|
| Precision | >99% methylation detection sensitivity | ~85% sensitivity for deletion detection only |
| Methodology | Methylation-Specific PCR (MS-PCR) | Fluorescence In Situ Hybridization |
| Turnaround Time | 12 Working Days | 10โ14 Working Days |
Physician Insight & Safety Protocols
"Methylation-specific PCR is the definitive molecular standard for confirming Prader-Willi syndrome. However, comprehensive clinical correlation with growth parameters, developmental history, and formal genetic counseling is essential for optimal patient management."
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA ID: 9294403
โ ๏ธ Medication & Therapy Advisory
Patients and caregivers must not discontinue prescribed medications, including growth hormone therapy, thyroid supplements, or antiepileptic drugs, without explicit consultation with the treating physician. Abrupt cessation of therapy can precipitate serious metabolic or neurological complications in individuals with PWS.
Exclusion Criteria & Emergency Red Flags
- Samples must be refrigerated (2โ8ยฐC) and never frozen; hemolyzed or clotted whole blood specimens will be rejected.
- An incomplete or missing Genomics Clinical Information Requisition Form (Form 20) will delay testing.
- Seek emergency care immediately if the child develops severe hypotonia, acute feeding difficulties, or respiratory distress. These symptoms indicate potential PWS complications requiring urgent medical intervention, not test-related issues.
Patient FAQ & Clinical Guidance
1. What does the Prader-Willi methylation test detect, and how accurate is it?
This test directly identifies abnormal methylation patterns at chromosome 15q11-q13 with 99.9% diagnostic sensitivity, confirming PWS in over 99% of typical clinical cases.
2. Is home blood collection available for children in Dubai or Abu Dhabi?
Yes, our VIP mobile phlebotomy service covers all Emirates with specially trained pediatric phlebotomists. Whole blood samples are collected using temperature-controlled cold-chain logistics to ensure specimen integrity.
3. How long does it take to get the results?
Results are typically reported within 12 working days from sample receipt. You will receive a secure notification via WhatsApp or the patient portal once the report is ready for download.
UAE Regulatory & Data Privacy Adherence
This service strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent protocols follow Federal Decree-Law No. 4 of 2016 on Medical Liability. All genetic data is processed within secure, ISO-accredited systems at DNA Labs UAE.
Clinical & Logistical Metadata
| Test Name | Prader-Willi Syndrome Methylation-Specific PCR |
| Price (AED) | 1,800 AED |
| Turnaround Time | 12 Working Days |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA tube) |
| Methodology Used | Methylation-Specific PCR (MS-PCR) |
| ICD-10-CM Code | Q87.1 |
| LOINC Code | 33582-0 |
| DHA Facility License & Address | Facility No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians