Test Price
2,800 AEDโ Home Collection Available
HTRA2 Gene (PARK13) Parkinson Genetic Test in UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing using Next Generation Sequencing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection โ available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by a Consultant Medical Geneticist and Genetic Counsellor.
- Price: 2,800 AED โ inclusive of genetic counselling and DHA-compliant report.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The HTRA2 (PARK13) Genetic Test screens for pathogenic variants in the HTRA2 gene, which are associated with early-onset autosomal recessive Parkinson disease. This next-generation sequencing analysis offers unparalleled resolution for patients with a family history of neurological disorders or unexplained parkinsonian symptoms, helping to clarify diagnosis and guide personalised care.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | 99.9% analytical sensitivity (NGS full-gene sequencing) | ~95% via targeted PCR / Sanger single-exon analysis |
| Methodology | Next-Generation Sequencing (NGS) with bioinformatic variant classification (ACMG 2026) | Sanger sequencing or PCR-based hotspot panels |
| Turnaround Time | 3 to 4 Weeks (with genetic counselling integration) | 4 to 6 Weeks (often without integrated counselling) |
Physician Insight & Safety Protocols
โIdentifying a pathogenic HTRA2 variant provides meaningful insight into your neurological health trajectory, but the result must always be interpreted in the full context of your clinical presentation and family pedigree. I personally review every genetic report to ensure you receive clear, compassionate guidance, alongside a referral pathway to a neurologist if warranted. This test serves as a critical piece of the diagnostic mosaic โ not a standalone verdict.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA: 9294403)
โ ๏ธ Medication Safety Advisory
Do not discontinue prescribed medication without consulting your doctor. Abrupt changes to dopaminergic therapy can lead to serious withdrawal effects or neuroleptic malignant-like syndrome. Always discuss your genetic results with your treating neurologist before any medication adjustments.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Pregnancy, recent blood transfusion or bone marrow transplant within the last 3 months, active systemic infection, inability to provide informed consent, known bleeding disorder incompatible with venepuncture.
- Emergency Red Flags: If you experience sudden confusion, severe headache, slurred speech, chest pain, or difficulty breathing at any point before or after sample collection, seek immediate emergency medical attention or call 998.
Patient FAQ & Clinical Guidance
1. What does a positive HTRA2 variant mean for my Parkinson risk?
A positive HTRA2 variant indicates an increased genetic predisposition to early-onset Parkinson disease, but does not guarantee symptom development; environmental and epigenetic factors play a significant modulating role. Genetic counselling is strongly advised to contextualise the finding within your personal and family health history.
2. How are the test results delivered and who interprets them?
Your HTRA2 genetic results are available within 3 to 4 weeks from sample receipt. A consultant medical geneticist and a genetic counsellor will jointly interpret the report and schedule a telephonic session to explain the findings, address your questions, and outline any recommended follow-up steps.
3. Is home blood collection safe and approved under UAE law?
Yes, our DHA-licensed phlebotomists perform home blood collection under strict ISO-certified cold-chain protocols ensuring sample integrity and compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 concerning the Use of Information and Communication Technology in Health Fields.
4. Can this test replace a clinical diagnosis from a neurologist?
No. This genetic test provides supportive molecular evidence but cannot substitute for a comprehensive neurological evaluation, including clinical examination, imaging, and family history assessment. The final diagnosis lies with your treating physician.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under the regulatory oversight of the Dubai Health Authority (DHA) and complies with all applicable federal health-data legislation, including:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) โ ensuring your genetic data is processed lawfully, transparently, and stored securely.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields โ governing the confidentiality and integrity of electronic health records.
- Federal Decree-Law No. 4 of 2016 on Medical Liability โ which establishes the framework for safe clinical testing practices and informed patient consent.
All laboratory procedures adhere to ISO 15189 standards, and your sample is processed in a CAP-accredited facility to guarantee result accuracy.
Clinical & Logistical Metadata
| Test Name | HTRA2 Gene (PARK13) Parkinson Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA tube); VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM โ 11 PM) |
| Methodology Used | Next-Generation Sequencing (NGS) โ Full-Gene Sequencing with ACMG 2026 variant classification |
| ICD-10-CM Code | G20, G21.8 |
| LOINC Code | 59049-0 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians