Test Price
2,800 AED✅ Home Collection Available
SDHB Gene (Paraganglioma Type 4) Next‑Generation Sequencing Test in UAE | 2,800 AED
Executive Summary & Core Metrics
- Analytical Sensitivity: >99.9% for all pathogenic single‑nucleotide and copy‑number variants across the full SDHB coding region.
- Price: 2,800 AED (inclusive of genetic counselling and post‑test oncologist consult).
- Logistics: VIP mobile phlebotomy & temperature‑controlled cold‑chain home collection, available daily 8 AM–11 PM.
- DHA License: Facility 1143, Dubai Healthcare City – fully regulated under UAE health law.
Test Overview & Methodology
The SDHB gene test employs Illumina‑based next‑generation sequencing (NGS) to interrogate the entire coding region and splice junctions. This single‑tube assay detects germline loss‑of‑function mutations that confer hereditary paraganglioma‑pheochromocytoma type 4 syndrome. With 100% coding‑region coverage and a limit of detection of 5% variant allele frequency, it provides the highest standard for heritable cancer risk assessment in the GCC region.
| Feature | Our Test (NGS Full Gene) | Conventional Single‑Site Test |
|---|---|---|
| Methodology | NGS (Illumina, 100% coding region coverage) | Targeted mutation analysis (limited hotspots) |
| Clinical Sensitivity | >99% for all pathogenic SNVs & CNVs | 60–70% (misses rare/novel variants) |
| Turnaround Time | 3–4 weeks | 5–7 weeks |
| Sample Type | Blood (EDTA), DNA, or FTA card | Blood only |
| Post‑Test Support | Genetic counselling & oncologist guidance | Often absent |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA 9294403: “A positive SDHB result is not a diagnosis—it is a powerful map for tailored surveillance. I always couple the genomic data with a three‑generation pedigree and discuss psychological readiness. Your emotional health is as important as the allele frequency.”
Advisory: Medication Safety Notice
⚠ Medication Safety
Do not stop any prescribed antihypertensives, beta‑blockers, or other medications without consulting your physician. This test refines risk awareness—do not use it to alter your treatment plan without medical supervision.
Exclusion Criteria & Emergency Red Flags
Do not proceed if:
- Patient unable to give informed consent (legal guardian required).
- Blood transfusion within the past 2 weeks.
- Active, untreated hypertensive crisis with palpitations or severe headache—ER first.
Seek emergency care for:
- Sudden severe headache, sweating, rapid heartbeat (catecholamine surge possible).
- Blood pressure >180/120 mmHg.
- Chest pain, shortness of breath, syncope—call 998 immediately.
Patient FAQ & Clinical Guidance
1. What does the SDHB NGS test detect and how long until I receive results?
The test identifies germline pathogenic variants across the entire SDHB gene with >99.9% sensitivity. Results are typically delivered within 3–4 weeks after sample receipt.
2. Is a doctor’s referral or genetic counselling required before testing in the UAE?
A mandatory pre‑test genetic counselling session is needed to complete a family pedigree and obtain informed consent. A post‑test oncologist consultation is also included.
3. How is the sample collected and does insurance cover the cost?
Our VIP mobile phlebotomy team collects one tube of blood or a dried blood spot at your home. We verify insurance coverage via WhatsApp (+971 54 548 8731) before the draw.
UAE Regulatory & Data Privacy Adherence
This service fully complies with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 on the Use of Information and Communication Technology in Health Fields. All clinical data are processed under strict confidentiality and DHA license 1143. No health information is shared without explicit patient consent.
Clinical & Logistical Metadata
| Test Name | SDHB Gene (Paraganglioma Type 4) Full Gene Sequencing – NGS |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood (EDTA), genomic DNA, or dried blood spot (FTA) – VIP mobile phlebotomy home collection available |
| Methodology Used | Next‑Generation Sequencing (Illumina) – full coding region plus splice sites |
| ICD-10-CM Code | C75.5, D44.7, Z15.09 |
| LOINC Code | 89464-7 |
| DHA Facility License & Address | License #1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
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