Test Price
2,200 AED✅ Home Collection Available
HLA Panel Reactive IgG Antibodies (PRA) Class I Quantitative Test in UAE | 2,200 AED | DHA Licensed
Executive Summary & Core Metrics
Core Metrics Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Luminex SAB Processing
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily 8 AM to 11 PM)
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by a registered general practitioner
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
Test Overview & Methodology
The HLA Panel Reactive IgG Antibodies (PRA) Class I Quantitative test measures the percentage of anti-HLA class I IgG antibodies in serum. This assay is essential for evaluating pre-transplant sensitization and guiding donor selection in renal, cardiac, and other solid organ transplant programs. The methodology employs Luminex X-MAP Single Antigen Bead (SAB) technology, providing allele-level resolution with a diagnostic sensitivity exceeding 99.9%. Results are reported as a panel reactive antibody percentage (PRA %) alongside identification of specific HLA antibody specificities.
| Feature | Our Test (DNA Labs UAE) | Closest Alternative |
|---|---|---|
| Methodology | Luminex X-Map Single Antigen Bead (SAB) — DHA/MOHAP Standard | Complement-Dependent Cytotoxicity (CDC) — outdated, lower sensitivity |
| Precision | 99.9% Diagnostic Sensitivity, allele-level resolution | ~70–80% sensitivity, broad specificity only |
| Turnaround Time | 10–12 business days (includes reflex to single antigen if needed) | 5–7 days (often requires additional confirmatory testing) |
| Sample Requirement | 3 mL serum, refrigerated, collected at least 48 hours post-dialysis | Similar, but no specific dialysis timing advisory provided |
Physician Insight & Safety Protocols
“As a general practitioner, I emphasize that this test is a critical tool for risk stratification in transplant evaluation. Results must be interpreted by your transplant specialist in conjunction with crossmatch tests and clinical history. Always discuss findings with your nephrologist or transplant team before making any treatment decisions.”
— Dr. Ajay Singh, General Practitioner, DHA Registration ID: 36234132
⚠️ Medication Advisory
Do not discontinue prescribed immunosuppressive medication without consulting your doctor. Modifying immunosuppressants without supervision may trigger acute rejection. Always adhere to your prescribed regimen.
Exclusion Criteria & ER Red Flags
- If you experience fever, chills, or shortness of breath post-collection, seek immediate medical attention — these could indicate infection or rejection.
- Patients with active systemic infections (e.g., sepsis) should postpone non-urgent testing.
- Do not schedule blood draw within 48 hours of dialysis; this may alter antibody levels.
- Severe hemolysis or lipemia may invalidate results; repeat collection may be required.
Patient FAQ & Clinical Guidance
1. Why do I need an HLA antibody test before a kidney transplant?
A: This test detects pre-formed IgG antibodies against donor HLA class I, which can cause hyperacute rejection within minutes of transplantation. It is mandatory for transplant listing protocols in the UAE.
2. How should I prepare for the blood draw, and does dialysis timing matter?
A: Collect your blood at least 48 hours after your last dialysis session to ensure accurate antibody levels are not diluted by the dialysis process. No fasting is required.
3. What does a high PRA percentage mean for my transplant eligibility?
A: A high PRA (greater than 20%) indicates you are “sensitized” and may require desensitization protocols or a well-matched donor. Discuss your results with your transplant coordinator for personalised guidance.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All test results are handled with confidentiality and stored in secure, DHA-compliant systems. Patient consent is obtained in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | HLA Panel Reactive IgG Antibodies (PRA) Class I Quantitative |
| Price (AED) | 2,200 AED |
| Turnaround Time | 10–12 business days |
| Sample Type / Matrix | Serum (3 mL) |
| Methodology Used | Luminex X-MAP Single Antigen Bead (SAB) Multiplex Assay |
| ICD-10-CM Code | Z94.9 (Organ transplant status, unspecified) |
| LOINC Code | 29453-7 (HLA class I panel - PRA) |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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