Test Price
850 AED✅ Home Collection Available
Immunophenotyping by Flow Cytometry CD16+56 (NK Cell) Test in UAE | 850 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Summary: Immunophenotyping by Flow Cytometry CD16+56 (NK Cell) Test precisely quantifies natural killer cells as a percentage of lymphocytes, essential for evaluating unexplained recurrent pregnancy loss, hematological malignancies, and immune surveillance. Processed under ISO 9001:2015 certified protocols (INT/EGQ/2509DA/3139) with DHA-licensed physician oversight and result interpretation by our specialist clinical team.
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Test Overview & Methodology
Immunophenotyping by Flow Cytometry CD16+56 quantifies natural killer (NK) cells as a percentage of lymphocytes using six-color fluorescent-activated cell sorting (FACS) with CD45 gating. This high-precision method is critical for diagnosing and monitoring conditions such as unexplained recurrent pregnancy loss, hematological malignancies, and primary immunodeficiency syndromes. The testing protocol employs LC-MS/MS grade reagents and adheres to ISO 9001:2015 standards for reproducible, clinically actionable results.
| Feature | DNA Labs UAE – CD16+56 Test | Closest Alternative |
|---|---|---|
| Precision / Technique | 6-color FACS with CD45 gating (ISO 9001:2015) | Standard 4-color panel |
| Methodology | Fluorescent Flow Cytometry (LC-MS/MS grade reagents) | Basic flow cytometry |
| Turnaround Time | Same day (sample received by 9 AM) | 48–72 hours |
| Clinical Accreditation | DHA / MOHAP, ISO 9001:2015 (INT/EGQ/2509DA/3139) | Basic lab certification only |
Physician Insight & Safety Protocols
“As a specialist in diagnostic radiology with clinical expertise in oncologic evaluation, I recognize that NK cell quantification provides essential immunological data for guiding treatment decisions. However, results must always be interpreted within the context of your full medical history. Please discuss all findings with your referring physician to determine the most appropriate management strategy.”
— Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology | DHA Registration ID: 61713011
⚠️ Important Advisory
Do not discontinue or alter any prescribed medication without prior consultation with your treating physician. NK cell counts may be influenced by immunosuppressive therapies, recent infections, or vaccination status.
Exclusion Criteria & Emergency Indicators
- Active infection or recent vaccination (within 48 hours) may transiently alter NK cell counts and delay accurate assessment.
- Chemotherapy-induced neutropenia can falsely lower NK cell percentages – inform the laboratory of any recent oncologic treatment.
- Seek emergency care immediately if you experience unexplained fever, unusual bleeding, bruising, or severe fatigue while awaiting test results.
Patient FAQ & Clinical Guidance
1. What is the CD16+56 test used for?
Brief answer: The test measures the percentage of natural killer (NK) cells in your blood to help diagnose recurrent pregnancy loss, certain leukemias, and primary immunodeficiencies.
CD16 and CD56 are surface markers expressed on NK lymphocytes. Quantifying these cells assists gynecologists, oncologists, and hematologists in identifying immune-mediated causes of recurrent miscarriage, monitoring disease progression in hematological malignancies, and evaluating patients with suspected NK cell deficiency. Results are most clinically meaningful when interpreted alongside your full medical history and additional laboratory parameters.
2. How is the test performed?
Brief answer: A blood sample is collected and analyzed using six-color flow cytometry to provide a precise count of CD16+56 NK cells.
A venous blood sample (3 mL in Lavender top EDTA plus 3 mL in Green top Sodium Heparin) is collected by trained phlebotomists. The sample must be transported immediately at 18–22°C; do not refrigerate or freeze. In specific clinical scenarios, a bone marrow aspirate (2 mL in Green top Sodium Heparin) may be required, which is performed exclusively in an accredited hospital setting. Analysis is conducted using fluorescent-activated cell sorting with CD45 gating for high specificity. Results are reported the same day when samples are received by 9 AM.
3. What do abnormal NK cell results mean?
Brief answer: Elevated NK cell levels may be associated with recurrent pregnancy loss or autoimmune conditions, while decreased levels can indicate immunodeficiency or bone marrow disorders.
Elevated percentages of CD16+CD56+ NK cells are frequently observed in women with unexplained recurrent miscarriage and certain autoimmune diseases. Conversely, reduced NK cell counts may signal primary immunodeficiency syndromes, bone marrow failure states, or the effects of immunosuppressive medications. These results must always be correlated with clinical history, physical examination findings, and complementary laboratory tests. Your physician will determine whether a referral to a hematologist or clinical immunologist is warranted.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance Framework
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – all patient data processed in strict compliance with UAE privacy regulations.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – secure handling of electronic health records and diagnostic data.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – clinical testing safety, informed consent, and physician accountability standards.
- ISO 9001:2015 Quality Management System – certified (Cert: INT/EGQ/2509DA/3139) for laboratory processes and data integrity.
- DHA Facility License No. 1143 – fully licensed by the Dubai Health Authority for diagnostic immunophenotyping services.
Clinical & Logistical Metadata
| Test Name | Immunophenotyping by Flow Cytometry CD16+56 (NK Cell) Test |
| Price (AED) | 850 AED |
| Turnaround Time | Same day (sample received by 9 AM) |
| Sample Type / Matrix | Peripheral whole blood (3 mL Lavender top EDTA + 3 mL Green top Sodium Heparin) or bone marrow aspirate (2 mL Green top Sodium Heparin). Bone marrow collection is a hospital-only procedure; mobile home phlebotomy is available for blood samples only. |
| Methodology Used | 6-Color Fluorescent Flow Cytometry (FACS) with CD45 Gating, ISO 9001:2015 |
| ICD-10-CM Code | D47.9 |
| LOINC Code | 8122-4 |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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