Test Price
2,800 AED✅ Home Collection Available
SPTBN5 Gene Neuronal Migration Disorder Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
Exceptional Accuracy – 99.9% diagnostic sensitivity through ISO 9001:2015 certified processing.
Premium Logistics – VIP mobile phlebotomy & temperature‑controlled cold‑chain home collection (daily 8 AM – 11 PM).
Clinical Support – Post‑analysis telephonic consultation with a genetic specialist for result interpretation.
Insurance Verification – Direct coverage inquiry via WhatsApp at +971 54 548 8731.
Executive Summary: The SPTBN5 gene sequencing service utilises cutting‑edge next‑generation sequencing (NGS) technology, compliant with Dubai Health Authority standards and UAE federal data protection frameworks, ensuring superior diagnostic accuracy and absolute data confidentiality.
Test Overview & Methodology
The SPTBN5 gene encodes β‑V spectrin, a cytoskeletal scaffold critical for neuronal migration and cortical lamination; pathogenic variants cause lissencephaly spectrum disorders with intractable epilepsy and profound developmental delay. Our targeted Genetic Test delivers complete coding‑region coverage, producing a definitive molecular diagnosis in 3–4 weeks with ACMG‑compliant reporting.
| Feature | Our Test (SPTBN5 NGS) | General Brain Malformation Panel |
|---|---|---|
| Precision | High‑depth targeted sequencing with Sanger validation | Broad capture; may have lower coverage for SPTBN5 |
| Turnaround Time | 3–4 weeks | 4–6 weeks |
| Cost | 2,800 AED | ≈4,500 AED |
| Clinical Utility | Directly answers SPTBN5‑associated neuronal migration disorder | Incidental findings may require secondary analysis |
Physician Insight & Safety Protocols
Medication Advisory
⚠ Do not discontinue prescribed medication without consulting your doctor. Genetic results complement, not replace, clinical judgement.
Patient Safety & Exclusion Criteria
- Acute medical instability or active infection at time of collection
- Bleeding diathesis or severe coagulopathy (if blood draw required)
- Lack of informed consent or inability to provide legal authorization
- Minors without guardian consent – in full compliance with UAE medical consent regulations
- Seek emergency care if: sudden neurological deterioration, status epilepticus, or severe phlebotomy‑site haemorrhage.
Patient FAQ & Clinical Guidance
1. What does the SPTBN5 gene test detect?
The SPTBN5 NGS test detects sequence variants and small deletions/duplications in the SPTBN5 gene linked to neuronal migration disorders. It analyzes all coding exons and splice junctions, classifying variants according to ACMG guidelines. The report highlights pathogenic or likely pathogenic changes that explain lissencephaly, microcephaly, and associated epilepsy syndromes, enabling accurate genetic counselling and family planning.
2. How long does it take to get results, and how are they reported?
Results are typically available within 3–4 weeks from sample receipt, delivered as a clinical report with ACMG variant classification. The report includes a detailed interpretation, zygosity, and clinical correlation recommendations. A post‑test telephonic consultation with a genetic specialist is included to explain the implications and next steps.
3. Is home collection available in Dubai and Abu Dhabi?
Yes, our VIP mobile phlebotomy team provides hospital‑grade home collection across all UAE emirates, including Dubai and Abu Dhabi. The service operates daily from 8 AM to 11 PM, using ISO‑certified cold‑chain transport to maintain sample stability. Appointments can be scheduled via WhatsApp at +971 54 548 8731.
UAE Regulatory & Data Privacy Adherence
This genetic test service operates in strict compliance with:
- Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring patient data confidentiality, lawful processing, and secure storage.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing the secure handling of digital health records and telemedicine components.
- Federal Decree‑Law No. 4 of 2016 on Medical Liability – defining responsibilities for diagnostic accuracy and patient consent.
All laboratory procedures meet ISO 15189 and local quality standards. For any privacy concerns, contact our Data Protection Officer at privacy@dnalabsuae.com.
Clinical & Logistical Metadata
| Test Name | SPTBN5 Gene Neuronal Migration Disorder Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood (3–5 mL in EDTA) – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection |
| Methodology Used | Targeted Next‑Generation Sequencing (NGS) with Sanger confirmation; ACMG variant classification |
| ICD‑10‑CM Code | Q04.8 (Other specified congenital malformations of brain) |
| LOINC Code | 21523-3 (Hereditary disease sequence analysis) |
| DHA Facility License & Address | DHA Facility License Number: 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE Corporate Lab Branding: DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians