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Test Price

3,200 AED

✅ Home Collection Available

Eukaryotic mRNA Sequencing – Ultra Low Input in Dubai | 3,200 AED

Executive Summary & Core Metrics

Executive Summary:

Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).

Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).

Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation with DHA-licensed specialists.

Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731 (Reply within 5 minutes).

Test Overview & Methodology

Eukaryotic mRNA Sequencing – Ultra Low Input profiles the complete transcriptome from as little as 10 picograms of RNA using UMI-based SMART-Seq v4 library preparation and Illumina NovaSeq X Plus sequencing. This test empowers molecular geneticists and oncologists to detect gene fusions, alternative splicing, and expression signatures in rare or precious samples.

Feature Our Test Standard RNA-Seq
Input Requirement 10 pg – 1 ng total RNA 100 ng – 1 µg total RNA
Sensitivity 99.9% at >5 read depth ~95%; drops with low input
Methodology SMART-Seq v4 + UMI + NovaSeq X Plus Poly-A selection + standard library
Turnaround Time 5 weeks 8–10 weeks

Physician Insight & Safety Protocols

Physician Insight

“Ultra-low input mRNA sequencing offers a detailed snapshot of gene expression from minimal RNA quantities. This technology enhances the diagnostic yield for gene fusions and splicing anomalies but should always be interpreted alongside clinical history and complementary findings. A genetic counseling session is recommended to fully correlate results with your health profile.”

— Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403

Advisory Protocols

⚠️ Medication Advisory

Do not discontinue prescribed medication without consulting your doctor. Heparin-based anticoagulants may interfere with library preparation; disclose all medications during pre-test consultation.

🚨 Safety Exclusion Criteria & ER Red Flags

  • Exclusion Criteria: Active bleeding disorder, severe anemia (Hb <7 g/dL), known allergy to phlebotomy supplies, inability to give informed consent (minors require guardian consent per Federal Decree-Law No. 4 of 2016 on Medical Liability).
  • Sample Integrity: Blood must be drawn in a PAXgene Blood RNA Tube or Tempus Blood RNA Tube. Do not use EDTA or heparin tubes – invalidates RNA quality.
  • ER Red Flags: Seek emergency care if you experience severe dizziness, fainting, or prolonged bleeding at the puncture site after home collection.

Patient FAQ & Clinical Guidance

1. What is eukaryotic mRNA sequencing – ultra low input, and which specialists need it?

A: Ultra-low input mRNA sequencing profiles the complete transcriptome from miniscule RNA quantities (10 pg), enabling molecular geneticists and oncologists to uncover rare gene fusions, alternative splicing, and expression signatures from limited samples like liquid biopsies or circulating tumor cells. The test uses SMART-Seq v4 chemistry and Illumina NovaSeq X Plus to capture full-length polyadenylated RNA, delivering gene expression quantification with high sensitivity and reproducibility. Clinical correlation with histopathology and genomic findings is essential.

2. How should I prepare for the test and what sample is required?

A: Collect whole blood into an RNA-stabilizing tube (PAXgene/Tempus) and stop heparin for 48 hours to guarantee high-quality RNA integrity and accurate sequencing. Fasting is not required, but inform your phlebotomist about all medications. Our home collection team brings the correct tube and ensures cold chain transport (2–8°C) to the lab within 4 hours.

3. How long do results take and what do they reveal?

A: Results are delivered within 5 weeks and provide a comprehensive gene expression profile including differentially expressed genes, fusion transcripts, and alternative splicing events critical for therapeutic decisions. The report includes normalized count matrices, pathway enrichment analysis, and a clinically annotated summary for oncologists and geneticists. Access your secure PDF via our patient portal; a post-test teleconsultation with a medical genetics specialist can be booked at no extra cost.

UAE Regulatory & Data Privacy Adherence

Data Privacy & Security Compliance

Your genetic and health data are protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All sequencing data is encrypted and stored on secure, UAE-hosted servers. Patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.

Clinical & Logistical Metadata

Test Name Eukaryotic mRNA Sequencing – Ultra Low Input
Price (AED) 3,200
Turnaround Time 5 weeks
Sample Type / Matrix Whole blood (PAXgene/Tempus RNA Tube) or Purified total RNA (10 pg – 1 ng)
Methodology Used SMART-Seq v4; UMI-based library preparation; Illumina NovaSeq X Plus Sequencing
ICD-10-CM Code Z01.89
LOINC Code 44702-4
DHA Facility License & Laboratory Address License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE

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