Test Price
2,800 AED✅ Home Collection Available
LMNA Gene Limb‑Girdle Muscular Dystrophy Type 1B (LGMD1B) Genetic Test in UAE | AED 2800 | DHA Licensed
Executive Summary & Core Metrics
Test Overview & Methodology
The LMNA gene LGMD1B NGS test comprehensively sequences the entire LMNA gene using next‑generation sequencing to identify pathogenic variants responsible for autosomal dominant limb‑girdle muscular dystrophy type 1B. This analysis provides definitive molecular diagnosis, guides disease‑specific management, and enables accurate family risk assessment.
| Feature | Our Test – LMNA NGS (LGMD1B) | Closest Alternative – Sanger Sequencing (Selected Exons) |
|---|---|---|
| Precision | Full‑gene coverage, detects point mutations, small indels, and copy‑number variants (CNVs) | Limited to pre‑selected exons; misses deep intronic variants and large rearrangements |
| Methodology | Next‑Generation Sequencing (NGS) with bioinformatic confirmation | Sanger (dideoxy) sequencing, lower throughput |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
Pre‑Test Requirements
A documented clinical history and a mandatory genetic counselling session to draw a pedigree chart of family members affected with limb‑girdle muscular dystrophy type 1B are required before sample collection. This complies with UAE healthcare regulations and ensures accurate interpretation.
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I understand the anxiety that comes with genetic testing for a progressive muscle disorder. This test provides essential diagnostic clarity, but results must always be correlated with your clinical symptoms and family history. I strongly advise discussing the findings with your neurologist or clinical geneticist to define the right care plan.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
⚠️ Important Safety Advisory
Do not discontinue any prescribed medication (e.g., cardiac, respiratory, or anti‑inflammatory drugs) without consulting your treating physician. Genetic testing does not replace ongoing clinical management.
🚨 Exclusion Criteria & Emergency Red Flags
- Exclusion: Individuals under 18 years without legal guardian consent and mandatory genetic counselling (per UAE Child Rights Law).
- Exclusion: Patients with acute life‑threatening conditions (unstable angina, respiratory failure) – stabilise medically before considering elective genetic testing.
- Red Flags – Seek Immediate Emergency Care: Sudden chest pain, severe palpitations, fainting, extreme shortness of breath, or rapid progression of muscle weakness leading to falls or swallowing difficulty.
Patient FAQ & Clinical Guidance
1. What is the LMNA gene test and what does it detect?
The LMNA gene NGS test detects mutations linked to autosomal dominant limb‑girdle muscular dystrophy type 1B for accurate genetic diagnosis. This test analyses the entire LMNA coding region to confirm the molecular cause of LGMD1B, guiding treatment and family planning.
2. How should I prepare for the LMNA gene test?
No special physical preparation is required; however, mandatory genetic counselling is needed to document family pedigree and clinical history. You will attend a pre‑test counselling session to sign informed consent and review the implications.
3. How long do results take and who interprets them?
Results are ready within 3 to 4 weeks. They are interpreted by a consultant medical geneticist, followed by a post‑test counselling session to discuss findings and next steps.
UAE Regulatory & Data Privacy Adherence
This test is performed under DHA Facility License 1143 at DNA Labs UAE. All patient data is handled in strict compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability. The laboratory maintains ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | LMNA Gene (LGMD1B) NGS Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral whole blood (3 mL EDTA tube) – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily 8 AM–11 PM |
| Methodology Used | Next‑Generation Sequencing (NGS) with bioinformatic confirmation |
| ICD‑10‑CM Code | G71.0 (Muscular dystrophy, including LGMD1B) |
| LOINC Code | 88215-1 (LMNA gene targeted mutation analysis) |
| DHA Facility License & Laboratory Address | DHA License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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