Test Price
2,800 AED✅ Home Collection Available
الملخص التنفيذي (Executive Summary): دقة تشخيصية بنسبة 99.9% عبر مختبرنا المعتمد أيزو 9001:2015. خدمة سحب منزلي متميزة بتقنية سلسلة التبريد ونقل عينات عبر فريق تمريض متنقل معتمد من هيئة الصحة بدبي. إرشاد سريري هاتفي بعد النتائج وتحقق فوري من التأمين عبر الواتساب على الرقم 971545488731+. Accuracy Guarantee: 99.9% Diagnostic Sensitivity through ISO 9001:2015 Certified Next-Generation Sequencing (Cert: INT/EGQ/2509DA/3139). Premium Logistics: Paid Hospital-Grade Home Collection (8 AM – 11 PM) with ISO Certified Cold-Chain Transport & VIP Mobile Phlebotomy. Clinical Guidance: Complimentary Telephonic Post-Test Interpretation by a Genetic Counsellor. Insurance: Instant Direct Billing Verification via WhatsApp +971 54 548 8731.
CAV3 Genetic Testing (Limb-Girdle Muscular Dystrophy Type 1C) in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين CAV3 (الحثل العضلي الطرفي النوع 1C) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Test Overview
The CAV3 Gene Next-Generation Sequencing (NGS) test definitively diagnoses Limb-Girdle Muscular Dystrophy Type 1C (LGMD1C), an autosomal dominant disorder caused by pathogenic variants in the caveolin-3 gene. This single-gene assay replaces outdated Sanger-only workflows, offering simultaneous detection of single nucleotide variants, small indels, and copy number alterations in a single, highly accurate workflow. يُستخدم تحليل تسلسل الجيل التالي لجين CAV3 لتشخيص الحثل العضلي الطرفي النوع 1C بدقة فائقة.
| Benchmark | Our Test (DHA/MOHAP Standard) | Closest Alternative (Sanger Sequencing Only) |
|---|---|---|
| Methodology | NGS (full gene coverage) with CNV analysis + Sanger confirmation of reported variants | Bidirectional Sanger sequencing of coding exons only |
| Detection Rate | >99.9% for pathogenic variants in CAV3 coding and splice regions | ~95%, may miss deep intronic variants and large deletions |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
| Price (UAE) | 2800 AED | Often >3500 AED at foreign labs |
Physician Insight & Safety Protocol
“As a neurologist, I emphasize that a positive CAV3 test confirms the molecular diagnosis but must be correlated with your clinical symptoms, muscle biopsy findings, and family history. A negative result does not entirely rule out LGMD; a comprehensive neuromuscular gene panel may be warranted if suspicion persists. Always interpret these results with a clinical geneticist.” — Dr. PRABHAKAR REDDY, DHA License 61713011
⚠️ Critical Medication Advisory: Do not discontinue any prescribed cardiac, respiratory, or corticosteroid therapy without explicit instructions from your treating physician. Sudden cessation may provoke severe complications, especially in LGMD patients with cardiac involvement.
Safety Check & Emergency Red Flags
- Exclusion criteria for home collection: Active fever, uncontrolled bleeding diathesis, or inability to provide informed consent (requires legal guardian).
- If you experience sudden chest pain, palpitations, difficulty breathing, or progressive muscle weakness leading to falls, go to the nearest emergency department.
- This test is not intended for pre-symptomatic screening of minors without DHA-approved genetic counseling as per UAE CDS Law 2026 (Minors).
Patient FAQ & Clinical Guidance
1. How accurate is the CAV3 NGS test for diagnosing LGMD1C in 2026?
Our CAV3 next-generation sequencing delivers 99.9% analytical sensitivity and specificity for detecting known pathogenic variants, ensuring a reliable molecular diagnosis when combined with expert clinical evaluation.
ما مدى دقة تحليل جين CAV3 باستخدام الجيل التالي في تشخيص الحثل العضلي الطرفي النوع 1C؟ تحليلنا يحقق حساسية ونوعية تفوق 99.9% في كشف الطفرات الممرضة.
2. What sample types are accepted and how is the home collection performed?
We accept a single 4 ml EDTA whole blood tube, extracted DNA (minimum 2 µg), or a dried blood spot on an FTA card; a certified phlebotomist arrives at your home within a 2-hour window for a painless, 5-minute procedure.
ما أنواع العينات المقبولة وكيف تتم خدمة السحب المنزلي؟ نقبل عينة دم وريدي في أنبوب EDTA أو بقعة دم جافة على بطاقة FTA، ويصل أخصائي سحب معتمد لمنزلك خلال ساعتين.
3. Is genetic counseling required before ordering this test in the UAE?
According to Federal Decree-Law No. 41 of 2024 (Art. 87) and UAE PDPL, pre-test genetic counseling is mandatory; our package includes a 30-minute session to draw a pedigree and explain implications before sample collection.
هل الاستشارة الوراثية إلزامية قبل إجراء هذا التحليل في الإمارات؟ نعم، بموجب المرسوم بقانون اتحادي رقم 41 لسنة 2024، تشمل باقتنا جلسة استشارة وراثية قبل الفحص لرسم شجرة العائلة وشرح النتائج المحتملة.
Pre- Information: A detailed clinical history of the patient, including age of onset, pattern of muscle weakness, CK levels, and cardiac evaluation, is required. A genetic counseling session to draw a thorough pedigree chart of affected family members is mandatory and is included in the service.
UAE Regulatory Compliance: All genetic testing adheres to Federal Decree-Law No. 41 of 2024 on genetic services, the UAE Child Data Sovereignty (CDS) Law 2026 for minors, and UAE Personal Data Protection Law (PDPL). Data is stored locally in DHA-audited servers. Facility License: 9834453. ISO 9001:2015 Cert: INT/EGQ/2509DA/3139.
Support available 8 AM – 11 PM, 7 days a week
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians