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Test Price

2,800 AED

✅ Home Collection Available

HCRT Gene Narcolepsy DNA Test (NGS) in UAE | 2800 AED | DHA Licensed

Executive Summary & Core Metrics

  • Diagnostic Accuracy: 99.9% analytical sensitivity for HCRT gene mutations using ISO‑certified NGS processing.
  • Home Collection: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
  • Clinical Support: Complimentary telephonic post‑test interpretation with a Consultant Medical Geneticist.
  • Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
  • Price: 2,800 AED (all‑inclusive, no hidden charges).

Test Overview & Methodology

This advanced genetic test sequences the entire coding region of the hypocretin (HCRT) gene using Next‑Generation Sequencing to identify mutations linked to narcolepsy type 1 (with cataplexy). Conducted under ISO‑certified protocols, it delivers clinically actionable results in 3–4 weeks, guiding diagnosis and familial risk assessment.

Feature Our Test (NGS) HLA‑DQB1*06:02 Typing
Genetic Target Full HCRT gene (coding exons) Single HLA allele
Method NGS + Sanger confirmation PCR‑SSP / Luminex
Clinical Utility Detects causative mutations; enables family screening Susceptibility marker only
Turnaround Time 3 – 4 weeks 1 – 2 weeks
Price (AED) 2,800 ~1,500

Physician Insight & Safety Protocols

Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA 9294403: “Genetic testing for HCRT mutations must be integrated with comprehensive sleep studies and neurological evaluation. A negative result does not exclude narcolepsy, as other genes or environmental factors can contribute; always correlate findings with clinical symptoms. This test is a valuable piece of the diagnostic puzzle, not a standalone verdict. Pre‑test genetic counselling is essential for informed decision‑making.”

⚠ Critical Safety Notice

Do not discontinue or adjust any prescribed sleep, neurological, or psychiatric medications without consulting your treating physician. This genetic test is not a replacement for professional medical management.

Exclusion Criteria

  • Individuals under 18 years without legal guardian consent and pre‑test genetic counselling (as required by Federal Law No. 2 of 2019).
  • Prenatal diagnosis (test not validated for fetal samples).
  • Asymptomatic individuals with no family history of narcolepsy.

Emergency Red Flags

  • Sudden loss of muscle tone (cataplexy) causing falls or injury.
  • Hallucinations, sleep paralysis, or micro‑sleep episodes while driving.
  • Severe daytime sleepiness that disrupts daily activities – seek immediate neurological care.

Patient FAQ & Clinical Guidance

1. What is the HCRT gene narcolepsy test?

This test sequences the HCRT gene to identify mutations causing narcolepsy type 1, providing definitive molecular confirmation and guiding familial risk assessment.

2. How accurate is this test?

Our NGS‑based assay achieves >99.9% analytical sensitivity and specificity for single‑nucleotide variants and small indels, validated under ISO 9001:2015 quality systems.

3. Do I need a specialist referral?

A referral from a neurologist or sleep medicine specialist is mandatory; we also provide pre‑test genetic counselling to comply with UAE genetic testing regulations.

4. What sample type is required?

A standard peripheral whole blood sample (3–5 mL in EDTA tube) is required. VIP home collection or clinic visit are both available.

5. How long do results take?

Turnaround time is 3 to 4 weeks from sample receipt, due to the complexity of NGS and confirmatory Sanger sequencing.

UAE Regulatory & Data Privacy Adherence

Data Protection & Health Information Governance

All genetic data is handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and clinical safety are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.

DNA Labs UAE is fully DHA‑licensed (License No. 1143) and operates under ISO 15189:2012 quality standards for medical laboratories.

Clinical & Logistical Metadata

Test Name HCRT Gene Narcolepsy (NGS) DNA Test
Price (AED) 2,800
Turnaround Time 3 – 4 weeks
Sample Type / Matrix Peripheral whole blood (EDTA tube)
Methodology Used Next‑Generation Sequencing (NGS) + Sanger confirmation
ICD-10-CM Code G47.411 (Narcolepsy with cataplexy)
LOINC Code 81432-9 (Narcolepsy type 1 genetic susceptibility test)
DHA Facility License & Address License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate: DNA Labs UAE

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