Test Price
2,800 AED✅ Home Collection Available
FLVCR1 Gene Posterior Column Ataxia with Retinitis Pigmentosa (PCARP) Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Accuracy Guarantee
99.9% Diagnostic Sensitivity and 100% clinical specificity via ISO 9001:2015 accredited NGS processing with independent Sanger validation.
Premium Logistics
VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM). Dried Blood Spot (FTA card) option for remote areas.
Clinical Guidance
Telephonic post-test clinical guidance with a consultant medical geneticist to interpret variant significance and plan follow-up.
Insurance Support
Direct billing verification via WhatsApp at +971 54 548 8731 (all major UAE networks).
Test Overview & Methodology
This test uses next‑generation sequencing (NGS) to analyse the entire coding region of the FLVCR1 gene, the definitive molecular diagnosis for posterior column ataxia with retinitis pigmentosa (PCARP) – a progressive neurodegenerative disorder combining sensory ataxia and retinal degeneration.
| Feature | Our FLVCR1 NGS Test | Closest Alternative: Single‑Gene Sanger Sequencing |
|---|---|---|
| Precision | Full coding region ± CNV detection, 99.9% analytical sensitivity | Only targeted known variants; misses novel mutations and large rearrangements |
| Method | NGS (Illumina NovaSeq X) + Sanger confirmation | Sanger sequencing of selected exons only |
| Turnaround Time | 3 – 4 weeks | 4 – 6 weeks |
| Clinical Utility | Diagnosis confirmation, family cascade testing, reproductive planning | Limited to known family mutation; negative result does not rule out disease |
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I confirm that identification of biallelic pathogenic FLVCR1 variants provides a definitive molecular diagnosis for PCARP. Clinical severity varies significantly; a comprehensive neurological and ophthalmological evaluation remains essential for prognosis and management. For minors, genetic testing under UAE law requires documented parental consent and pre-test genetic counseling per Federal Decree-Law No. 4 of 2016 on Medical Liability.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Medication Warning
Do Not Discontinue Prescribed Medication Without Consulting Your Doctor
This genetic test requires only DNA; however, any neurological or ophthalmological drugs should be continued as directed to avoid rebound symptoms or acute decompensation. Always discuss medication management with your treating physician.
Exclusion Criteria & ER Red Flags
- Exclusion: Whole blood sample is not suitable if the patient received a blood transfusion within the last 7 days; alternatively, collected DNA or an FTA card can be used.
- Exclusion: Active severe infection or chemotherapy causing extreme leukopenia may compromise DNA quality; consider extracted DNA from a previous sample.
- If you experience sudden loss of vision, severe unsteady gait leading to falls, or new‑onset breathing difficulties, proceed directly to the nearest emergency department – do not wait for test results.
- For minors under 18, UAE Federal Decree-Law No. 4 of 2016 on Medical Liability mandates written parental consent and a court‑approved genetic counseling record before sample collection.
Patient FAQ & Clinical Guidance
1. What does the FLVCR1 gene test detect and how reliable is it?
This NGS test detects all pathogenic and likely pathogenic variants across the entire FLVCR1 gene with 99.9% analytical sensitivity, providing a definitive molecular diagnosis for PCARP. It identifies single nucleotide variants, small insertions/deletions, and copy number variations. All clinically significant findings are double‑confirmed by Sanger sequencing. A negative result in a patient with typical symptoms may still warrant whole‑exome sequencing to uncover alternative genetic etiologies.
2. Is a genetic counseling session mandatory before sample collection?
Yes, a mandatory pre‑genetic counseling session is required to draw a detailed pedigree chart and explain the autosomal recessive inheritance pattern to all tested individuals. This session helps assess the risk for other family members and facilitates informed consent. It can be conducted via encrypted video call in English or Arabic. Without this counseling, the laboratory will not process the sample.
3. How do I arrange home blood collection and verify insurance coverage?
Simply send a WhatsApp message to +971 54 548 8731; our team confirms your insurance policy’s genetic testing coverage and dispatches a DHA‑licensed phlebotomist to your preferred location between 8 AM and 11 PM. You can choose whole blood (1 purple‑top EDTA tube), or a pain‑free finger‑prick dried blood spot card for children or remote areas. Cold‑chain logistics maintain sample integrity at 2‑8°C from door to lab. All personal genetic data is processed in compliance with UAE Personal Data Protection Law (PDPL), and results are shared exclusively with the ordering physician unless you consent otherwise.
UAE Regulatory & Data Privacy Adherence
- Licensed by Dubai Health Authority (DHA) Facility License Number: 1143.
- ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). Rigorous quality management ensures result reproducibility.
- Full compliance with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields for secure health data handling.
- Data privacy strictly in accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – all genomic data encrypted, de‑identified, and stored on secure servers within the UAE.
- Consent and safety standards follow Federal Decree-Law No. 4 of 2016 on Medical Liability for all clinical testing, including mandatory counseling and informed consent for minors.
Clinical & Logistical Metadata
| Test Name | FLVCR1 Gene Sequencing – Posterior Column Ataxia with Retinitis Pigmentosa (PCARP) |
| Price (AED) | 2,800 |
| Turnaround Time | 3 – 4 weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA), extracted DNA, or Dried Blood Spot (FTA card) |
| Methodology Used | Next‑Generation Sequencing (NGS) on Illumina NovaSeq X with Sanger confirmation |
| ICD-10-CM Code | G11.8 (Other hereditary ataxia) |
| LOINC Code | 94288-3 (FLVCR1 gene analysis) |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – Corporate Lab Branding: DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians