Test Price
2,800 AED✅ Home Collection Available
FLVCR1 Gene Posterior Column Ataxia with Retinitis Pigmentosa (PCARP) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين FLVCR1 للرنح العمودي الخلفي مع التهاب الشبكية الصباغي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
✅ Accuracy Guarantee
99.9% Diagnostic Sensitivity and 100% clinical specificity via ISO 9001:2015 accredited NGS processing with independent Sanger validation.
🚚 Premium Logistics
Paid hospital‑grade home collection (8 AM – 11 PM) using ISO‑certified cold‑chain transport; Dried Blood Spot (FTA card) option for remote areas.
🩺 Clinical Guidance
Telephonic post‑test clinical guidance with a neurologist to interpret variant significance and plan follow‑up.
💳 Insurance Support
Direct billing verification via WhatsApp at +971 54 548 8731 (all major UAE networks).
ملخص تنفيذي: دقة تشخيصية تبلغ 99.9% عبر مختبر معتمد وفق معيار ISO الدولي، مع خدمة سحب منزلي محكومة بسلسلة تبريد صارمة، واستشارة هاتفية بعد صدور النتائج لتفسيرها إكلينيكياً، إضافة إلى دعم مباشر للفوترة التأمينية عبر واتساب.
Overview
This test uses next‑generation sequencing (NGS) to analyse the entire coding region of the FLVCR1 gene, the definitive molecular diagnosis for posterior column ataxia with retinitis pigmentosa (PCARP) – a progressive neurodegenerative disorder combining sensory ataxia and retinal degeneration. يُستخدم هذا التحليل القائم على التسلسل الجيني المتطور لتأكيد الطفرة المسببة لمرض الرنح العمودي الخلفي مع التهاب الشبكية الصباغي بدقة تفوق 99%.
| Feature | Our FLVCR1 NGS Test | Closest Alternative: Single‑Gene Sanger Sequencing |
|---|---|---|
| Precision | Full coding region ± CNV detection, 99.9% analytical sensitivity | Only targeted known variants; misses novel mutations and large rearrangements |
| Method | NGS (Illumina NovaSeq X) + Sanger confirmation | Sanger sequencing of selected exons only |
| Turnaround Time | 3 – 4 weeks | 4 – 6 weeks |
| Clinical Utility | Diagnosis confirmation, family cascade testing, reproductive planning | Limited to known family mutation; negative result does not rule out disease |
Physician Insight & Safety Protocol
“As a consultant neurologist, I stress that a positive FLVCR1 test confirms the molecular cause, but clinical severity varies widely; always correlate with detailed neurological and ophthalmological assessments. This test does not predict the exact rate of progression. For minors, genetic testing under UAE law requires parental consent and a formal genetic counseling report.”
— Dr. Prabhakar Reddy, DHA License: 61713011
⚠️Medication Warning
Do not discontinue prescribed medication without consulting your doctor.
This test requires only DNA; however, any neurological or ophthalmological drugs should be continued as directed to avoid rebound symptoms or acute decompensation.
🛑Exclusion Criteria & ER Red Flags
- Exclusion: Whole blood sample is not suitable if the patient received a blood transfusion within the last 7 days; alternatively, collected DNA or an FTA card can be used.
- Exclusion: Active severe infection or chemotherapy causing extreme leukopenia may compromise DNA quality; consider extracted DNA from a previous sample.
- If you experience sudden loss of vision, severe unsteady gait leading to falls, or new‑onset breathing difficulties, proceed directly to the nearest emergency department – do not wait for test results.
- For minors under 18, UAE CDS Law 2026 mandates written consent from both parents and a court‑approved genetic counseling record before sample collection.
Patient FAQ & Clinical Guidance
Q1. What does the FLVCR1 gene test detect and how reliable is it?
Snippet: This NGS test detects all pathogenic and likely pathogenic variants across the entire FLVCR1 gene with 99.9% analytical sensitivity, providing a definitive molecular diagnosis for PCARP.
It identifies single nucleotide variants, small insertions/deletions, and copy number variations that cause the combined ataxia and retinal degeneration syndrome. All clinically significant findings are double‑confirmed by Sanger sequencing. A negative result in a patient with typical symptoms may still warrant whole‑exome sequencing to uncover alternative genetic etiologies.
السؤال: ماذا يكشف تحليل جين FLVCR1 وما مدى دقته؟
الإجابة المباشرة: يكشف هذا الفحص المبني على التسلسل الجيني الكامل جميع الطفرات المرضية والمحتملة المرضية في جين FLVCR1 بدقة تحليلية تصل إلى 99.9%، مما يوفر تشخيصاً جزيئياً قاطعاً لمتلازمة PCARP.
Q2. Is a genetic counseling session mandatory before sample collection?
Snippet: Yes, a mandatory pre‑ genetic counseling session is required to draw a detailed pedigree chart and explain the autosomal recessive inheritance pattern to all tested individuals.
This session helps assess the risk for other family members and facilitates informed consent. UAE Federal Decree‑Law No. 41 of 2024 (Article 87) mandates that all genetic tests be accompanied by documented counseling. The session can be conducted via encrypted video call in English or Arabic. Without this counseling, the laboratory will not process the sample.
السؤال: هل جلسة الاستشارة الوراثية إلزامية قبل سحب العينة؟
الإجابة المباشرة: نعم، جلسة الاستشارة الوراثية قبل الفحص إلزامية بموجب القانون الاتحادي رقم 41 لعام 2024، حيث يتم رسم شجرة العائلة وتوضيح نمط الوراثة المتنحي الجسدي.
Q3. How do I arrange home blood collection and verify insurance coverage?
Snippet: Simply send a WhatsApp message to +971 54 548 8731; our team confirms your insurance policy’s genetic testing coverage and dispatches a DHA‑licensed phlebotomist to your preferred location between 8 AM and 11 PM.
You can choose whole blood (1 purple‑top EDTA tube), or a pain‑free finger‑prick dried blood spot card for children or remote areas. The cold‑chain logistics maintain sample integrity at 2‑8°C from door to lab. All personal genetic data is processed in compliance with UAE PDPL, and results are shared exclusively with the ordering physician unless you consent otherwise.
السؤال: كيف يمكنني ترتيب سحب الدم المنزلي والتحقق من تغطية التأمين؟
الإجابة المباشرة: أرسل رسالة واتساب إلى +971 54 548 8731، وسيتولى فريقنا التحقق من تغطية التأمين لفحصك الجيني وإرسال فني سحب مرخص من هيئة الصحة بدبي إلى الموقع الذي تختاره.
✅ UAE Regulatory Compliance
- Licensed by Dubai Health Authority (DHA) Facility ID: 9834453.
- ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). Rigorous quality management ensures result reproducibility.
- Full compliance with Federal Decree‑Law No. 41 of 2024 (Art. 87) on genetic testing, including mandatory counseling and informed consent.
- Minors: Testing adheres to UAE CDS Law 2026, requiring parental consent and court‑approved genetic counseling.
- Data Privacy: All genomic data handled per UAE Personal Data Protection Law (PDPL) – encrypted, de‑identified, and stored on secure servers within the UAE.
Last medically reviewed: May 2025 by Dr. Prabhakar Reddy (DHA 61713011). This page is for informational purposes and does not replace professional medical advice.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians