Test Price
2,800 AED✅ Home Collection Available
CLN6 Gene Neuronal Ceroid Lipofuscinosis Type 6 (NCL6) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين CLN6 (الداء الليفي الشحمي العصبي النوع 6) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- 99.9% Diagnostic Sensitivity – Next‑Generation Sequencing (NGS) processed under ISO 9001:2015 accredited protocols.
- Premium Logistics: Paid Hospital‑Grade Home Collection via ISO Certified Cold‑Chain Home Collection and VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Telephonic post‑test clinical correlation and genetic counselling by DHA‑licensed practitioners.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ملخص تنفيذي: فحص جيني دقيق بنسبة 99.9% لتسلسل جين CLN6 باستخدام تقنية الجيل التالي (NGS) في مختبر معتمد وفق معايير ISO 9001:2015. خدمة سحب منزلي متميزة واستشارة وراثية عن بُعد.
Comprehensive Test Overview
This CLN6 gene next‑generation sequencing test detects pathogenic variants in the CLN6 gene responsible for neuronal ceroid lipofuscinosis type 6, a rare, inherited neurodegenerative lysosomal storage disorder. It enables early molecular diagnosis, carrier detection, and informed prenatal planning for at‑risk families in the United Arab Emirates.
| Feature | Our Test (Amrita Labs ISO‑Accredited) | Closest Alternative (Single‑Gene Sanger Sequencing) |
|---|---|---|
| Precision / Sensitivity | ≥99.9% detection of SNVs, indels, and CNVs across all coding exons ±10 bp flanking regions | ~95% for point mutations only; limited indel/CNV resolution |
| Methodology | Next‑Generation Sequencing (NGS) with bioinformatic confirmation and Sanger validation of variants | Conventional Sanger sequencing (exon‑by‑exon), lower throughput |
| Turnaround Time | 3 to 4 Weeks | 5 to 7 Weeks |
| Clinical Reporting | DHA‑compliant with ICD‑10 E75.4, LOINC 72498‑6, and genetic counselling integration | Basic variant report without counselling support |
| UAE Regulatory Adherence | Federal Decree‑Law No. 41/2024, CDS Law 2026 (Minors), UAE PDPL compliant | Often lacks local statutory safeguards |
Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY (DHA License: 61713011) – Clinical Geneticist:
“As a clinical geneticist, I want to emphasise that a positive result must be correlated with detailed neurological examination, brain imaging, and family history. A negative result does not exclude other genetic forms of Batten disease or deep intronic variants. This test is a powerful diagnostic compass, but only a comprehensive clinical evaluation can guide the next steps—please involve your neurologist and genetic counselor before acting on any findings.”
⚠️ IMPORTANT MEDICATION WARNING
Do not discontinue prescribed medication without consulting your doctor. Genetic results are supplementary and should never replace ongoing clinical management.
Safety & Exclusion Criteria
- Exclusion Criteria: This test is not suitable for individuals who have undergone allogeneic bone marrow transplant or where somatic mosaicism for CLN6 is suspected. For minors, genetic counselling and written guardian consent are mandatory under UAE Federal Decree‑Law No. 5 of 2026 (Child Rights Law, Wadeema’s Law).
- ER Red Flags: This test does not cause acute symptoms. However, if you experience new‑onset seizures, rapid vision deterioration, or developmental regression, seek immediate emergency care—these indicate possible disease progression, not a reaction to the blood draw.
Pre‑Test Requirements
A clinical history and a genetic counselling session to draw a pedigree chart of family members affected with neuronal ceroid lipofuscinosis type 6 are mandatory before sample collection. No fasting or special diet is required for the blood draw.
Accepted Sample Types: Whole Blood (EDTA tube) or Extracted DNA or One drop Blood on FTA Card.
Patient FAQ & Clinical Guidance
1. What is the CLN6 Gene Genetic Test and why is it important?
Direct Answer: This next‑generation sequencing test analyzes the entire CLN6 gene for pathogenic mutations causing neuronal ceroid lipofuscinosis type 6, a rare, progressive disorder, enabling early diagnosis and accurate carrier identification. (هذا الفحص الجيني يحدد الطفرات المسببة للمرض في جين CLN6 لتشخيص الداء الليفي الشحمي العصبي مبكراً).
2. How is the home blood collection performed and what preparation is needed?
Direct Answer: Our DHA‑licensed phlebotomist performs a painless venipuncture at your doorstep between 8 AM and 11 PM; no fasting or special preparation is required beyond providing a brief medical history. (يتم سحب عينة الدم منزلياً على يد ممرض مرخص دون الحاجة إلى صيام، فقط تقديم التاريخ الطبي).
3. Can the test be done for children and what are the results implications?
Direct Answer: Yes, with mandatory pre‑test genetic counselling and parental consent per UAE law, this identifies affected children and silent carriers, providing a foundation for early intervention and reproductive planning. (نعم، يمكن إجراء الفحص للأطفال بعد الاستشارة الوراثية وموافقة الوالدين، مما يساعد في التدخل المبكر والتخطيط الأسري).
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians