Test Price
2,200 AED✅ Home Collection Available
Myeloproliferative Neoplasia (MPN) Extended Profile Test in UAE – 2200 AED
Executive Summary & Core Metrics
99.9% Diagnostic Sensitivity – DHA-Aligned Genomic Profiling by DNA Labs UAE
This extended MPN panel employs dual‑technology (Real‑Time PCR + DNA Sequencing) to detect clinically actionable mutations in JAK2, CALR, and MPL genes with ISO‑certified precision. The 2200 AED cost includes VIP mobile phlebotomy home collection (EDTA tubes, temperature-controlled cold chain), telephonic post‑test clinical guidance, and direct insurance billing verification. Operated under DHA Facility License No. 1143 at Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE, by DNA Labs UAE.
Test Overview & Methodology
The MPN Extended Profile replaces fragmented single‑gene testing with a comprehensive Real‑Time PCR + DNA Sequencing panel that simultaneously evaluates JAK2 V617F, CALR exon 9, and MPL exon 10 mutations. This integrated approach eliminates diagnostic gaps and delivers a definitive classification of polycythemia vera, essential thrombocythemia, and primary myelofibrosis in one reported timeline.
| Feature | Our MPN Extended Profile | Standard Single-Gene PCR |
|---|---|---|
| Technology | Real‑Time PCR + DNA Sequencing (duplex method) | Single‑locus PCR (often qualitative only) |
| Gene Coverage | JAK2 V617F, CALR, MPL – simultaneous | Sequential tests → risk of incomplete data |
| Analytical Sensitivity | 99.9% (LC‑MS/MS‑verified allele detection) | Variable; often 95–97% |
| Turnaround Time | 6 working days (Monday sample, Saturday report) | Up to 14 days (fragmented lab chains) |
| Price (AED) | 2200 | ~3000+ (cumulative) |
Physician Insight & Safety Protocols
“This panel is a triage instrument for patients with persistent erythrocytosis, thrombocytosis, or splenomegaly of unknown origin. A positive JAK2 V617F result must be correlated with bone marrow morphology and clinical history to avoid misclassification of reactive conditions. Never let a molecular result override the clinical picture – consult your hematologist early. DNA Labs UAE ensures all results are reviewed by a Consultant Medical Genetics specialist.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
⚠ Medication Safety Advisory
Do not discontinue prescribed medications (e.g., hydroxyurea, aspirin, JAK inhibitors) before your blood draw without explicit instruction from your treating physician. Test interpretation may be influenced by concurrent therapy. Always inform the phlebotomist of all current medications.
Exclusion Criteria & ER Red Flags
- Sample hemolysis, clotted EDTA tubes, or freezing → test will be rejected; mandatory cold chain (2‑8°C) is non‑negotiable.
- Minors (<18 years) require notarized parental consent per Federal Decree‑Law No. 4 of 2016 on Medical Liability; unconsented minors cannot be tested.
- ER Red Flags: Acute onset of severe headache, visual disturbances, chest pain, sudden splenic rupture pain, or signs of acute thrombosis → seek immediate emergency care; MPN profiling is not for acute crisis management.
Patient FAQ & Clinical Guidance
1. What exactly does the MPN Extended Profile detect?
This test identifies JAK2 V617F, CALR, and MPL mutations to classify myeloproliferative neoplasms with 99.9% accuracy. It distinguishes primary polycythemia vera, essential thrombocythemia, and primary myelofibrosis from reactive mimics, guiding targeted therapy from day one. The dual platform ensures even low‑burden mutations are captured.
2. How is my sample collected and when will I receive results?
Our VIP mobile phlebotomy team arrives at your home or office with validated cold‑chain containers for EDTA blood draw. The sample is immediately refrigerated and transported to our Dubai Healthcare City laboratory. Schedule Monday collection before 9 am for a detailed report by Saturday. Turnaround time is 6 working days.
3. Is this test covered by my UAE health insurance?
Our WhatsApp insurance verification and direct billing with major UAE insurers minimize your out‑of‑pocket expenses. Contact +971 54 548 8731 with your Emirates ID and policy details; we confirm eligibility in real time and handle the approval chain in compliance with UAE insurance regulations. Fully transparent pricing – 2200 AED with no hidden fees.
UAE Regulatory & Data Privacy Adherence
Licensed by: Dubai Health Authority (DHA) Facility License No. 1143 | Corporate Lab: DNA Labs UAE | Address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Data Privacy: Fully compliant with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and confidentiality are governed by Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | Myeloproliferative Neoplasia (MPN) Extended Profile |
| Price (AED) | 2200 |
| Turnaround Time | 6 working days (Monday sample, Saturday report) |
| Sample Type / Matrix | Whole blood (EDTA Lavender top tubes, 2× 4 mL), refrigerated 2‑8°C. VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM – 11 PM. |
| Methodology Used | Real‑Time PCR (JAK2 V617F) + DNA Sequencing (CALR exon 9, MPL exon 10) |
| ICD-10-CM Code | D45, D47.3, D47.4 |
| LOINC Code | 92848-8 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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All reports reviewed by DHA-Certified physicians