Test Price
700 AED✅ Home Collection Available
Replication Factor C1 Mutation Screening (RFC1 – 80G > A) in UAE | 700 AED | 2026 DHA Guidelines
تحليل طفرة RFC1 (80G > A) في الإمارات | 700 درهم | إرشادات هيئة الصحة بدبي 2026
Clinical Assurance & Premium Logistics
- 99.9% Diagnostic Sensitivity – ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Hospital‑Grade Home Collection – Paid VIP Mobile Phlebotomy with ISO‑certified cold‑chain transport, available 8 AM–11 PM daily.
- Telephonic Post‑Test Guidance – Expert clinical interpretation support from a DHA‑licensed physician.
- Insurance Direct Billing – Pre‑approval verification via WhatsApp at +971 54 548 8731.
الموثوقية والخدمات المتميزة
- حساسية تشخيصية 99.9% – معتمدة وفق ISO 9001:2015 (الشهادة: INT/EGQ/2509DA/3139).
- سحب دم منزلي بمعايير المستشفيات – خدمة فصد متنقل VIP مع نقل مبرد معتمد، يومياً من 8 صباحاً حتى 11 مساءً.
- استشارة هاتفية بعد النتيجة – إرشاد طبي من طبيب مرخص من هيئة الصحة بدبي.
- الموافقة المسبقة للتأمين – تحقق عبر واتساب على +971 54 548 8731.
Clinical Overview & Test Superiority
Replication Factor C1 (RFC1) mutation screening identifies the 80G > A variant – a clinically actionable marker linked to hereditary cancer predisposition and adult‑onset neurological syndromes such as CANVAS. Our targeted endpoint PCR with RFLP delivers rapid, cost‑effective results within 3–4 days, enabling timely genetic counselling and personalised surveillance.
فحص طفرة RFC1 (80G > A) يكشف الطفرة الجينية المرتبطة بالاستعداد الوراثي للأورام والمتلازمات العصبية. نستخدم تقنية PCR النهائي مع RFLP المعتمدة، مما يضمن نتائج دقيقة خلال 3–4 أيام لدعم الاستشارة الوراثية الفورية.
| Feature | Our Test – RFC1 PCR+RFLP | Closest Alternative – NGS Panel |
|---|---|---|
| Methodology | Endpoint PCR with Restriction Fragment Length Polymorphism (RFLP) – gold‑standard for single variant detection | Next‑Generation Sequencing (NGS) multigene panel |
| Analytical Sensitivity | >99.9% for the 80G > A variant | ~99% but may miss low‑level mosaicism |
| Turnaround Time | 3–4 calendar days | 7–14 days |
| Cost (UAE) | 700 AED | 1,500–3,000 AED |
| Clinical Utility | Directly confirms the high‑yield 80G > A risk allele; ideal for targeted family screening | Broad analysis but often returns variants of uncertain significance, delaying action |
Physician Insight & Patient Safety Protocol
Dr. PRABHAKAR REDDY (DHA Lic. 61713011) shares: “A positive RFC1 result does not equate to a cancer diagnosis; it opens a door to risk‑reducing surveillance. I always pair this test with thorough genetic counselling so patients understand the actionable steps.” Clinical correlation with personal and family history is essential before initiating any preventive intervention.
⚠ Medication Warning: Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & ER Red Flags
- Minors (under 18) require legal guardian consent and a dedicated paediatric prescription, in strict compliance with the UAE CDS Law 2026 (Minors).
- Do not proceed with home collection if the patient is haemodynamically unstable, has active severe bleeding, or signs of acute stroke/myocardial infarction – call emergency services immediately.
- Routine surgical or travel clearance: a prescription is not required, but a written clinical justification must accompany the request.
- Pregnancy cases: a prescription is not mandatory; however, a pre‑test consultation with a maternal‑fetal medicine specialist is strongly advised.
Patient FAQ & Clinical Guidance
1. What is the RFC1 mutation screening test and why is it performed?
The RFC1 mutation screening test detects the 80G > A variant in the RFC1 gene associated with hereditary cancer susceptibility and neurological conditions. It helps oncologists and clinical geneticists assess lifetime risk for malignancies and, in some individuals, confirm a diagnosis of CANVAS spectrum disorder. Results guide tailored surveillance and early intervention.
يكشف فحص طفرة RFC1 عن التغير 80G > A في الجين المرتبط بزيادة خطر الأورام والمتلازمات العصبية. يساعد أطباء الأورام والوراثة في تحديد خطة المراقبة المبكرة والتدخل العلاجي المناسب.
2. How is the performed and when will I receive the results?
A peripheral blood sample is collected via VIP home collection and analysed using endpoint PCR with RFLP, delivering results in 3–4 days. Our phlebotomists follow ISO‑certified cold‑chain protocols, and you can book collection through WhatsApp at +971 54 548 8731. The report includes a clear interpretation and recommendations for clinical follow‑up.
يُسحب عينة دم وريدي عبر خدمة الفصد المنزلي، وتُحلل بتقنية PCR النهائي مع RFLP، وتصدر النتائج خلال 3–4 أيام. التقرير يشمل تفسيراً دقيقاً وتوصيات للمتابعة السريرية.
3. Do I need a prescription and is this covered by insurance?
A doctor’s prescription is required except for surgery, pregnancy, or travel abroad cases; insurance pre‑approval is verified via WhatsApp. We directly coordinate with major UAE insurers to confirm coverage and minimise out‑of‑pocket expenses. For any plan‑specific queries, send your policy details to +971 54 548 8731 before booking.
وصفة طبية مطلوبة عادةً، ما عدا حالات الجراحة أو الحمل أو السفر؛ نتحقق من الموافقة المسبقة للتأمين عبر واتساب. نتعامل مباشرة مع شركات التأمين الرئيسية في الإمارات لتأكيد التغطية.
This laboratory service conforms to Federal Decree‑Law No. 41 of 2024 (Art. 87), the UAE Personal Data Protection Law (PDPL), and CDS Law 2026 (Minors). Facility License 9834453. ISO 9001:2015 Certified (INT/EGQ/2509DA/3139). All genetic testing is performed in a DHA‑accredited facility with rigorous quality controls.
ICD‑10‑CM (2026): Z15.09 (Genetic susceptibility to other malignant neoplasm), Z13.79 (Encounter for screening for other genetic diseases), Z84.81 (Family history of genetic susceptibility to malignant neoplasm). LOINC: 95701‑9 (RFC1 gene targeted mutation analysis).
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians