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Test Price

2,800 AED

✅ Home Collection Available

TRAPPC11 Gene Limb‑Girdle Muscular Dystrophy, Autosomal Recessive Type 2S (LGMD‑2S) Genetic Test in UAE | 2,800 AED | DNA Labs UAE

Executive Summary & Core Metrics

Executive Summary & Core Metrics

  • Accuracy: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
  • Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
  • Clinical Guidance: Telephonic Post-Test Clinical Guidance by a DHA-licensed Consultant Medical Geneticist.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The TRAPPC11 Gene NGS Test utilizes next‑generation sequencing (NGS) to provide comprehensive coverage of the TRAPPC11 gene. This method identifies single nucleotide variants, insertions, deletions, and copy number variations associated with autosomal recessive limb‑girdle muscular dystrophy type 2S (LGMD‑2S). The assay enables precise diagnosis, prognosis, and family risk stratification.

Feature Our TRAPPC11 NGS Test (ISO‑Lab) Closest Alternative (Standard Genetic Screening)
Methodology Next‑Generation Sequencing (NGS) – full gene coverage Sanger sequencing of selected exons or targeted panel
Diagnostic Precision 99.9% analytical sensitivity & >99% specificity Variable; may miss deep intronic or copy‑number variants
Turnaround Time 3–4 Weeks 4–8 Weeks
Sample Type Whole Blood, DNA FTA Card, or Extracted DNA Whole Blood only

Physician Insight & Safety Protocols

Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403: “This NGS-based test provides critical insight into LGMD‑2S, a rare progressive muscle disorder. A genetic finding must always be correlated with the clinical presentation, electromyography, and muscle biopsy results. I strongly encourage families to pair the result with comprehensive genetic counselling to fully understand the inheritance pattern and implications for family planning. A negative result does not exclude other limb‑girdle dystrophies.”

Medication & Management Advisory

Do not discontinue any prescribed medication or alter your rehabilitation plan without consulting your treating neurologist.

Exclusion Criteria & Emergency Red Flags

  • Acute febrile illness or systemic infection within 48 hours before sample collection.
  • Known haematological malignancy requiring urgent specialist clearance.
  • Severe cutaneous condition at venipuncture site or extreme needle phobia (contact lab for alternative collection).
  • ER Red Flags: Sudden worsening muscle weakness, difficulty breathing or swallowing, dark cola‑coloured urine (rhabdomyolysis), or unexplained falls – seek emergency care immediately.

Patient FAQ & Clinical Guidance

1. What is the purpose of the TRAPPC11 gene test?

This test detects disease‑causing variants in the TRAPPC11 gene to confirm autosomal recessive limb‑girdle muscular dystrophy type 2S (LGMD‑2S). It aids in precise diagnosis, prognosis, and family risk stratification.

2. How is the sample collected and what preparation is needed?

A simple blood draw via VIP mobile phlebotomy or a DNA FTA card sample is required. No fasting or medication discontinuation is necessary.

3. How should I interpret the result and what are the next steps?

A positive result confirms the genetic basis of LGMD‑2S. A follow‑up with a clinical geneticist or neurologist is essential for management and family counselling.

UAE Regulatory & Data Privacy Adherence

Our Commitment to Compliance

  • Licensed by DHA/MOHAP – Facility License: 1143
  • ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139)
  • Data Privacy: Fully compliant with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
  • Patient Safety & Consent: Adheres to Federal Decree‑Law No. 4 of 2016 on Medical Liability.

Clinical & Logistical Metadata

Test Name TRAPPC11 Gene Limb‑Girdle Muscular Dystrophy, Autosomal Recessive Type 2S (LGMD‑2S) Genetic Test
Price (AED) 2,800
Turnaround Time 3–4 Weeks
Sample Type / Matrix Whole Blood, DNA FTA Card, or Extracted DNA
Methodology Used Next‑Generation Sequencing (NGS) – full gene coverage
ICD-10-CM Code G71.0 (Muscular dystrophy)
LOINC Code 81247-9 (Muscular dystrophy panel)
DHA Facility License & Address Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | License No. 1143

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