Test Price
2,800 AED✅ Home Collection Available
PDX1 Gene Maturity-Onset Diabetes of the Young Type 4 (MODY4) Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
🔬 Accuracy Guarantee
99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).
🚗 Premium Logistics
VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AM – 11 PM).
🧑⚕️ Clinical Guidance
Telephonic Post-Test Clinical Guidance by a Consultant Medical Geneticist.
💳 Insurance
Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The PDX1 (MODY4) genetic test detects pathogenic variants in the pancreatic and duodenal homeobox 1 gene, confirming maturity‑onset diabetes of the young type 4. This NGS-based assay provides a definitive molecular diagnosis, enabling precise clinical management and familial risk assessment. DNA Labs UAE utilizes next‑generation sequencing (NGS) for comprehensive analysis of all coding exons and splice‑site boundaries.
| Feature | Our PDX1 MODY4 NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Methodology | Next-Generation Sequencing (NGS) – full gene analysis | Sanger sequencing – limited to previously known variants |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Diagnostic Yield | >99.9% analytical sensitivity; detects novel mutations | ~85% sensitivity for known hot‑spots only |
| Cost (AED) | 2,800 | 3,500 – 5,000 |
Physician Insight & Safety Protocols
“As a Consultant Medical Geneticist, I recognize the importance of precise genetic diagnosis in young‑onset diabetes. This test identifies PDX1 mutations that guide targeted therapy and inform family screening. However, results must always be interpreted within the full clinical context and confirmed by a genetic counselor.”
⚠️ Medication Advisory
Do not discontinue or alter any prescribed diabetes medication without consulting your treating physician. This test provides diagnostic information, not treatment guidance.
Exclusion Criteria & Emergency Red Flags
- Patients under 18 years without consent of a legal guardian (per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Individuals unable to undergo mandatory pre‑test genetic counseling session.
- Seek immediate emergency care if you experience: vomiting, abdominal pain, altered consciousness, or signs of diabetic ketoacidosis; do not wait for test results.
Patient FAQ & Clinical Guidance
1. What does the PDX1 MODY4 test detect?
The PDX1 MODY4 genetic test uses next-generation sequencing to identify pathogenic mutations in the PDX1 gene responsible for monogenic diabetes. This comprehensive analysis scans all coding exons and splice‑site boundaries, distinguishing MODY4 from type 1 and type 2 diabetes. The result provides a definitive molecular diagnosis that informs treatment decisions and family screening.
2. How is the test performed and what is the turnaround time?
A simple blood sample is collected via our VIP Mobile Phlebotomy service (available daily 8 AM – 11 PM). The sample is transported under strict cold‑chain conditions to our ISO‑accredited laboratory. Turnaround time is 3–4 weeks from sample receipt.
3. Who should consider this test?
Individuals with MODY-compatible diabetes (diagnosed under 25 years, strong family history, negative autoantibodies) benefit from this screening. Endocrinologists, diabetologists, and primary care physicians may order the test when clinical features do not fit typical type 1 or type 2 diabetes. Genetic counseling is recommended before and after testing.
UAE Regulatory & Data Privacy Adherence
🔒 Data Privacy & Compliance
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL): All patient data is encrypted, access‑controlled, and processed in accordance with UAE data protection standards.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields: Our digital health systems comply with all ICT security and interoperability requirements.
- Federal Decree-Law No. 4 of 2016 on Medical Liability: All clinical procedures, including genetic testing and patient consent, adhere to the UAE medical liability framework.
Clinical & Logistical Metadata
| Test Name | PDX1 Gene Maturity-Onset Diabetes of the Young Type 4 (MODY4) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral whole blood (3–5 mL in EDTA tube) |
| Methodology Used | Next‑Generation Sequencing (NGS) – full gene analysis |
| ICD-10-CM Code | E13.9, E11.9 (differential coding) |
| LOINC Code | 88503-0 (Genetic analysis of specified gene) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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