Test Price
2,800 AED✅ Home Collection Available
MEN1 Genetic Test (NGS) for Multiple Endocrine Neoplasia Type 1 in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% sensitivity for point mutations and copy number variants via ISO 15189-accredited NGS workflow.
- Logistics Excellence: VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM.
- Post-Test Clinical Guidance: Telephonic consultation with our consultant medical geneticist to contextualize results.
- Direct Billing Support: Pre-authorization and insurance verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The MEN1 genetic test employs full-gene Next-Generation Sequencing (NGS) to detect germline mutations in the MEN1 gene, providing definitive risk assessment for multiple endocrine neoplasia type 1. This assay covers all coding exons, intronic boundaries, and promoter regions with an average read depth exceeding 500x, ensuring detection of single nucleotide variants, small insertions/deletions, and large structural rearrangements.
| Feature | Our Test (NGS) | Closest Alternative (Sanger/MLPA) |
|---|---|---|
| Methodology | Full-gene Next-Generation Sequencing | Targeted Sanger sequencing or MLPA |
| Diagnostic Precision | >99.9% sensitivity for point mutations & CNVs | ~85% sensitivity; limited structural variant detection |
| Turnaround Time | 3 to 4 weeks | 4 to 6 weeks |
| Pre-test Requirement | Mandatory genetic counseling & clinical history (pedigree) | Genetic counseling (often limited) |
Physician Insight & Safety Protocols
"Genetic testing for MEN1 is a powerful tool that must be paired with comprehensive endocrine evaluation and lifelong surveillance planning. A positive result does not equate to cancer – it is a guide for proactive management. Always interpret within full clinical context and family history."
— Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Medication Advisory
Do not discontinue any prescribed medications without consulting your physician. Genetic test results must always be correlated clinically and never used as sole basis for treatment changes.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Testing of minors without court-approved parental consent per UAE Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Exclusion: Acutely unwell individuals – postpone collection if febrile or in active endocrine crisis.
- Emergency: Symptoms of severe hypercalcemia (confusion, vomiting, abdominal pain) or sudden vision loss/headache (pituitary apoplexy) require immediate emergency care.
- Emergency: Dizziness, syncope, or severe palpitations in known MEN1 carriers require urgent cardiac/endocrine evaluation.
Patient FAQ & Clinical Guidance
1. Why is NGS used for MEN1 testing?
NGS enables comprehensive analysis of the entire MEN1 gene, detecting single nucleotide variants and small deletions with high sensitivity. This technology uncovers more than 95% of pathogenic mutations, ensuring that no clinically relevant variant goes undetected.
2. What is the sample requirement and turnaround time?
Our test accepts peripheral whole blood, extracted DNA, or dried blood spot on an FTA card. Results are available within 3 to 4 weeks. A simple venipuncture or finger-prick sample collected via our temperature-controlled home service ensures specimen stability from collection to laboratory.
3. Is genetic counseling required before testing?
A mandatory pre-test genetic counseling session is required to discuss implications, family history, and informed consent before sample collection. This session, conducted by a certified genetic counselor or our consultant medical geneticist, ensures you fully understand the risks, benefits, and limitations of the test, aligning with UAE federal regulations.
4. How do insurance and billing work for this test?
Our billing team offers direct insurance verification and pre-authorization support via WhatsApp at +971 54 548 8731. The test price is 2800 AED all-inclusive of genetic counseling, sample collection (including home visit if preferred), testing, and post-result teleconsultation.
UAE Regulatory & Data Privacy Adherence
This service is conducted in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access-restricted, and processed solely for diagnostic purposes under your explicit consent. Our laboratory holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) and is licensed by the Dubai Health Authority (License No. 1143).
Clinical & Logistical Metadata
| Test Name | MEN1 Genetic Test (NGS) for Multiple Endocrine Neoplasia Type 1 |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 weeks (typically 15-20 business days) |
| Sample Type / Matrix | Peripheral Whole Blood, Extracted DNA, or Dried Blood Spot (FTA card) |
| Methodology Used | Full-gene Next-Generation Sequencing (NGS) with CNV detection |
| ICD-10-CM Code | E31.20 (Multiple endocrine neoplasia type I, unspecified) |
| LOINC Code | 80382-5 (MEN1 gene mutation analysis) |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (DNA Labs UAE) |
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