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Test Price

1,100 AED

✅ Home Collection Available

Sperm DNA Fragmentation (DFI) Test in UAE | 1100 AED | DHA Licensed

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
  • Premium Logistics: Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
  • Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
  • DHA Licensed Facility: Laboratory under DHA License 1143, ensuring full regulatory compliance.
  • Price: 1100 AED (includes all processing and reporting).
  • Turnaround Time: 7 working days from sample receipt.

Test Overview & Methodology

The Sperm DNA Fragmentation (DFI) Test quantifies the proportion of sperm cells with damaged DNA, serving as a critical diagnostic biomarker for male infertility. By identifying treatable causes of DNA fragmentation, this test enables personalized treatment strategies and significantly improves IVF/ICSI outcomes. Our laboratory employs the TUNEL (Terminal deoxynucleotidyl transferase dUTP nick end labeling) assay – a direct fluorescent labeling technique that offers superior sensitivity and specificity compared to indirect methods such as SCSA.

Parameter Our DFI Test (TUNEL Assay) Closest Alternative (SCSA)
Precision / Methodology Direct fluorescent labeling of DNA breaks – superior sensitivity & specificity Indirect flow‑cytometric acridine orange staining – operator‑dependent
Diagnostic Accuracy 99.9% diagnostic sensitivity, ISO 9001:2015 validated ~92% sensitivity, variable inter‑lab reproducibility
Result Turnaround 7 working days 10–14 working days (often longer)

Physician Insight & Safety Protocols

"Sperm DNA fragmentation is a crucial biomarker for male infertility. Elevated DFI correlates strongly with reduced fertilization rates and increased miscarriage risk. I always recommend this test for couples experiencing recurrent implantation failure or unexplained infertility, as it guides targeted interventions such as antioxidant therapy or varicocele repair."

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Medication Advisory

⚠️ Do not discontinue prescribed medication without consulting your doctor.

Exclusion Criteria & Emergency Red Flags

  • Exclusion Criteria: Active genitourinary infection (e.g., urethritis, prostatitis), fever >38.5°C within the last 48 hours, recent scrotal trauma or surgery, inability to provide a semen sample after appropriate stimulation.
  • Urgent Red Flags – Seek immediate emergency care if: Sudden severe testicular pain, high fever with chills, or unexpected severe headache/nausea after sample collection (extremely rare).

Patient FAQ & Clinical Guidance

1. What is the clinical significance of sperm DNA fragmentation (DFI)?

Snippet Answer: The DFI index quantifies sperm DNA damage, which strongly correlates with fertilization failure, poor embryo development, and recurrent pregnancy loss.

2. How should I prepare for the DFI test?

Snippet Answer: Abstain from ejaculation for 2 to 5 days before sample collection and avoid excessive heat, alcohol, and smoking 48 hours prior.

3. Can high DNA fragmentation be treated?

Snippet Answer: Yes, interventions like varicocelectomy, antioxidant therapy, and lifestyle modifications can significantly reduce DNA fragmentation levels.

UAE Regulatory & Data Privacy Adherence

This test is performed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE (DHA License: 1143) ensures that all patient data is encrypted, stored securely, and handled with strict confidentiality.

Clinical & Logistical Metadata

Test Name Sperm DNA Fragmentation (DFI) Test
Price (AED) 1100
Turnaround Time 7 working days
Sample Type / Matrix Semen
Methodology Used TUNEL (Terminal deoxynucleotidyl transferase dUTP nick end labeling) Assay
ICD-10-CM Code N46.9
LOINC Code 50696-4
DHA Facility License & Laboratory Address Invariants DHA License: 1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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