Test Price
2,800 AED✅ Home Collection Available
HSPD1 Gene Leukodystrophy (Hypomyelinating Type 4) Genetic Test – 2800 AED
Executive Summary & Core Metrics
- 99.9% Diagnostic Sensitivity – ISO‑accredited ultra‑deep NGS covering all coding exons, splice‑site ±20 bp, and full‑gene CNV detection.
- Premium Home Collection – Hospital‑grade, ISO‑certified cold‑chain phlebotomy between 8 AM and 11 PM at your Dubai, Abu Dhabi, or Sharjah residence.
- Tele‑Guidance – Complimentary post‑test clinical result interpretation with a certified medical genetics consultant via secure tele‑consultation.
- Insurance Direct Billing Verification – WhatsApp your Emirates ID & insurance card to +971 54 548 8731 for instant confirmation.
Test Overview & Methodology
This targeted Next‑Generation Sequencing (NGS) assay thoroughly analyses the entire HSPD1 gene to detect pathogenic variants causing hypomyelinating leukodystrophy type 4 (HLD4). The result guides neurologists, genetic counsellors, and clinical researchers in establishing a definitive molecular diagnosis, enabling tailored management, family planning, and early neuroprotective strategies.
| Feature | UAE‑Best HSPD1 NGS (Current Test) | Closest Alternative (Single‑Gene Sanger) |
|---|---|---|
| Methodology | Ultra‑deep NGS with bioinformatic CNV calling | Conventional Sanger sequencing (misses large deletions/duplications) |
| Analytical Sensitivity | >99.9% for single‑nucleotide variants and indels; full‑gene CNV detection | ~98% for SNVs only; no CNV coverage |
| Turnaround Time | 3–4 weeks | 8–12 weeks (often batch‑dependent) |
| Sample Types | Whole blood, extracted DNA, dried blood spot on FTA card | Whole blood only |
| Price (UAE) | 2,800 AED | 3,500–4,800 AED (estimated) |
Physician Insight & Safety Protocols
"As a medical genetics consultant, I recognize the significant diagnostic odyssey that families endure when suspecting HLD4. This NGS test provides a precise molecular answer, but it must be interpreted alongside brain MRI findings and a complete clinical history. Patients and families should never discontinue any prescribed neuroprotective or symptomatic therapy without consulting their treating physician first, as abrupt changes may exacerbate white matter vulnerability."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Reg: 9294403
⚠️ Medication & Safety Advisory
Do not halt or modify any prescribed therapies (including anticonvulsants, corticosteroids, or neuroprotective regimens) prior to consulting your neurologist or genetic specialist. Abrupt cessation can lead to clinical deterioration in patients with hypomyelinating disorders.
🚨 Exclusion Criteria & Red Alerts
- Not for emergency use – this test cannot diagnose acute neurological crises; immediate ER evaluation is required for seizures, loss of consciousness, or rapid motor decline.
- Patients with ongoing neurologic instability must receive acute medical care first; genetic testing should not delay emergency interventions.
- Minors require a legal guardian’s consent under the UAE Medical Liability Law (Federal Decree-Law No. 4 of 2016).
- Inability to provide a multi‑generational family pedigree may limit the interpretive value of genetic counselling.
Patient FAQ & Clinical Guidance
1. What is the clinical utility of the HSPD1 leukodystrophy NGS test?
It provides a definitive molecular diagnosis of hypomyelinating leukodystrophy type 4, enabling accurate prognosis, family genetic counselling, and personalised neuroprotective management.
2. What is the typical turnaround time for results?
Results are delivered within 3 to 4 weeks from the date of sample receipt at our laboratory. Our VIP home collection and express processing ensure no unnecessary delays.
3. Do I need a doctor’s referral to order this test in the UAE?
Yes, a referral from a certified neurologist or genetic counsellor is mandatory under the UAE Medical Liability Law (Federal Decree-Law No. 4 of 2016) to ensure clinical appropriateness and valid informed consent.
UAE Regulatory & Data Privacy Adherence
All genetic data and personal information are handled in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your results are encrypted, stored securely, and accessed only by authorised clinical personnel. No third‑party data sharing occurs without your explicit consent.
Clinical & Logistical Metadata
| Test Name | HSPD1 Gene Leukodystrophy (Hypomyelinating Type 4) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood, extracted DNA, dried blood spot on FTA card |
| Methodology Used | Next‑Generation Sequencing (NGS) |
| ICD-10-CM Code | G93.89 |
| LOINC Code | 48018-6 (HSPD1 gene mutation analysis) |
| DHA Facility License & Laboratory Address | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DHA License: 1143 |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians