Test Price
850 AED✅ Home Collection Available
NPM1 Gene Mutation Quantitative MRD Monitor Test in UAE | 850 AED
Executive Summary & Core Metrics
- Diagnostic Sensitivity: 99.9% via ISO 9001:2015 certified RQ-PCR.
- Logistics: Hospital extraction only – sample collection strictly within accredited facility.
- Clinical Guidance: Post-test teleconsult with Consultant Medical Genetics for result interpretation.
- Insurance: Direct coverage verification via WhatsApp +971 54 548 8731.
- Price: 850 AED (all-inclusive, no hidden fees).
Test Overview & Methodology
The NPM1 Gene Mutation Quantitative MRD Monitor Test uses highly sensitive Real-Time PCR (RQ-PCR) to measure minimal residual disease (MRD) levels in patients with NPM1-mutated acute myeloid leukemia (AML). This assay provides critical insights for treatment response evaluation and early relapse prediction.
| Feature | DNA Labs UAE Test | Standard Hospital Lab |
|---|---|---|
| Methodology | Real-Time PCR (RQ-PCR) + optional WGS | RQ-PCR only |
| Sensitivity (MRD detection) | 10⁻⁴ to 10⁻⁵ (0.01% – 0.001%) | 10⁻³ (0.1%) |
| Turnaround Time | Sample Mon/Thu 11am ⇒ Report Wed/Sat | 5–7 working days |
| Accreditation | ISO 9001:2015, DHA/MOHAP compliant | Local hospital accreditation |
| Price | 850 AED | 950–1,200 AED (estimated) |
Physician Insight & Safety Protocols
“NPM1 MRD monitoring is the most sensitive predictor of relapse in AML. Interpretation must integrate the full clinical picture including morphology and additional genetic markers. Strict adherence to sample handling protocols is paramount – never freeze the EDTA tube – and correlation with historical MRD trends is essential for accurate risk stratification.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Advisory on Medication
Do not discontinue prescribed medication without consulting your doctor. This test is for monitoring only and does not replace clinical judgment.
Safety Exclusion Criteria & ER Red Flags
- Do not use frozen samples; hemolysis or clot may lead to inaccurate results.
- Ensure MRD Requisition Form 22 is fully completed; incomplete forms delay reporting.
- Seek immediate emergency care if experiencing uncontrolled bleeding, severe infection, or new neurological symptoms – these are unrelated to the test but indicate acute leukemia complications.
Patient FAQ & Clinical Guidance
1. Why is NPM1 MRD monitoring important after AML treatment?
NPM1 MRD status is the most powerful independent predictor of relapse in acute myeloid leukemia. Regular monitoring with RQ-PCR enables early detection of molecular recurrence months before clinical relapse, allowing preemptive intervention and tailored treatment intensity.
2. How should I prepare for the NPM1 MRD test?
No fasting is required. Your healthcare provider will collect a 5 mL blood sample in a lavender-top EDTA tube. Sample must be transported refrigerated, never frozen, and the mandatory MRD Requisition Form 22 must be fully completed with historical data. Note that sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety.
UAE Regulatory & Data Privacy Adherence
This service complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic and clinical data is processed securely under ISO 9001:2015 certified protocols (Cert: INT/EGQ/2509DA/3139). Patient confidentiality and data integrity are maintained at every stage.
Clinical & Logistical Metadata
| Test Name | NPM1 Gene Mutation Quantitative MRD Monitor |
| Price (AED) | 850 |
| Turnaround Time | Sample Mon/Thu 11am ⇒ Report Wed/Sat |
| Sample Type / Matrix | Hospital Extraction Only – Sample collection is conducted strictly within an accredited hospital facility; mobile home phlebotomy is disabled for safety. |
| Methodology Used | Real-Time PCR (RQ-PCR) |
| ICD-10-CM Code | C92.0 |
| LOINC Code | 78579-2 |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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