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KIR Genotyping Test

Original price was: 2,600 د.إ.Current price is: 2,340 د.إ.

-10%

The KIR Genotyping Test, available at DNA Labs UAE for a cost of 2340 AED, is a specialized diagnostic procedure designed to analyze the KIR (Killer-cell Immunoglobulin-like Receptors) genes. These genes play a crucial role in the immune system by regulating the activity of natural killer (NK) cells, which are essential for the body’s defense against tumors and virally infected cells. By determining the specific variations and types of KIR genes present in an individual, this test provides valuable insights into one’s immune system functionality and potential susceptibility to various diseases, including autoimmune disorders and certain types of cancer. The results from the KIR Genotyping Test can also be instrumental in transplant medicine, particularly in bone marrow or stem cell transplantation, by helping to predict transplant success and the risk of graft-versus-host disease. Conducted at the state-of-the-art facilities of DNA Labs UAE, the test is a significant tool for both medical research and personalized medicine, aiding in the development of tailored treatments and therapeutic strategies.

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KIR GENOTYPING Test

Cost: 2340.0 AED

Symptoms and Diagnosis

KIR genotyping is a genetic test that is used to determine an individual’s KIR (killer cell immunoglobulin-like receptor) gene profile. KIR genes are a group of genes that play a crucial role in the regulation of natural killer (NK) cells, which are a type of immune cell involved in the recognition and elimination of infected or abnormal cells.

The KIR genotyping test analyzes the specific variations or polymorphisms in the KIR genes to identify the presence or absence of different KIR gene alleles. These alleles can have different functional properties and can affect the individual’s immune response and susceptibility to certain diseases.

Test Details

  • Components: KIR GENOTYPING Test
  • Price: 2340.0 AED
  • Sample Condition: 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube. Ship refrigerated. DO NOT FREEZE.
  • Report Delivery: Sample Daily by 9 am; Report 2 Working days
  • Method: Luminex SSO
  • Test type: Transplantation Pathology
  • Doctor: Hematologist
  • Test Department: Pre Test Information
  • Pre Test Information: No special preparation required

How the Test Works

The KIR genotyping test is typically performed using a blood or saliva sample. The DNA from the sample is isolated and specific regions of the KIR genes are amplified using polymerase chain reaction (PCR). The amplified DNA is then sequenced or analyzed using techniques such as Sanger sequencing or next-generation sequencing to determine the specific KIR gene alleles present in the individual.

Clinical Applications

The results of the KIR genotyping test can provide valuable information about an individual’s immune system and can be used in various clinical and research settings. For example, it can help in assessing the compatibility between a donor and recipient for hematopoietic stem cell transplantation, as KIR genes are known to play a role in graft-versus-host disease and graft rejection.

It can also be used to study the association between specific KIR gene alleles and the risk or progression of certain diseases, such as autoimmune disorders, infectious diseases, and cancer.

Conclusion

Overall, KIR genotyping is a useful tool for understanding the genetic variations in the KIR genes and their implications in immune function and disease susceptibility.

Test Name KIR GENOTYPING Test
Components
Price 2340.0 AED
Sample Condition 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube. Ship refrigerated. DO NOT FREEZE.
Report Delivery Sample Daily by 9 am; Report 2 Working days
Method Luminex SSO
Test type Transplantation Pathology
Doctor Hematologist
Test Department:
Pre Test Information No special preparation required
Test Details

KIR genotyping is a genetic test that is used to determine an individual’s KIR (killer cell immunoglobulin-like receptor) gene profile. KIR genes are a group of genes that play a crucial role in the regulation of natural killer (NK) cells, which are a type of immune cell involved in the recognition and elimination of infected or abnormal cells.

The KIR genotyping test analyzes the specific variations or polymorphisms in the KIR genes to identify the presence or absence of different KIR gene alleles. These alleles can have different functional properties and can affect the individual’s immune response and susceptibility to certain diseases.

The KIR genotyping test is typically performed using a blood or saliva sample. The DNA from the sample is isolated and specific regions of the KIR genes are amplified using polymerase chain reaction (PCR). The amplified DNA is then sequenced or analyzed using techniques such as Sanger sequencing or next-generation sequencing to determine the specific KIR gene alleles present in the individual.

The results of the KIR genotyping test can provide valuable information about an individual’s immune system and can be used in various clinical and research settings. For example, it can help in assessing the compatibility between a donor and recipient for hematopoietic stem cell transplantation, as KIR genes are known to play a role in graft-versus-host disease and graft rejection. It can also be used to study the association between specific KIR gene alleles and the risk or progression of certain diseases, such as autoimmune disorders, infectious diseases, and cancer.

Overall, KIR genotyping is a useful tool for understanding the genetic variations in the KIR genes and their implications in immune function and disease susceptibility.