KIR GENOTYPING Test
Cost: 2340.0 AED
Symptoms and Diagnosis
KIR genotyping is a genetic test that is used to determine an individual’s KIR (killer cell immunoglobulin-like receptor) gene profile. KIR genes are a group of genes that play a crucial role in the regulation of natural killer (NK) cells, which are a type of immune cell involved in the recognition and elimination of infected or abnormal cells.
The KIR genotyping test analyzes the specific variations or polymorphisms in the KIR genes to identify the presence or absence of different KIR gene alleles. These alleles can have different functional properties and can affect the individual’s immune response and susceptibility to certain diseases.
Test Details
- Components: KIR GENOTYPING Test
- Price: 2340.0 AED
- Sample Condition: 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube. Ship refrigerated. DO NOT FREEZE.
- Report Delivery: Sample Daily by 9 am; Report 2 Working days
- Method: Luminex SSO
- Test type: Transplantation Pathology
- Doctor: Hematologist
- Test Department: Pre Test Information
- Pre Test Information: No special preparation required
How the Test Works
The KIR genotyping test is typically performed using a blood or saliva sample. The DNA from the sample is isolated and specific regions of the KIR genes are amplified using polymerase chain reaction (PCR). The amplified DNA is then sequenced or analyzed using techniques such as Sanger sequencing or next-generation sequencing to determine the specific KIR gene alleles present in the individual.
Clinical Applications
The results of the KIR genotyping test can provide valuable information about an individual’s immune system and can be used in various clinical and research settings. For example, it can help in assessing the compatibility between a donor and recipient for hematopoietic stem cell transplantation, as KIR genes are known to play a role in graft-versus-host disease and graft rejection.
It can also be used to study the association between specific KIR gene alleles and the risk or progression of certain diseases, such as autoimmune disorders, infectious diseases, and cancer.
Conclusion
Overall, KIR genotyping is a useful tool for understanding the genetic variations in the KIR genes and their implications in immune function and disease susceptibility.
Test Name | KIR GENOTYPING Test |
---|---|
Components | |
Price | 2340.0 AED |
Sample Condition | 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube. Ship refrigerated. DO NOT FREEZE. |
Report Delivery | Sample Daily by 9 am; Report 2 Working days |
Method | Luminex SSO |
Test type | Transplantation Pathology |
Doctor | Hematologist |
Test Department: | |
Pre Test Information | No special preparation required |
Test Details | KIR genotyping is a genetic test that is used to determine an individual’s KIR (killer cell immunoglobulin-like receptor) gene profile. KIR genes are a group of genes that play a crucial role in the regulation of natural killer (NK) cells, which are a type of immune cell involved in the recognition and elimination of infected or abnormal cells. The KIR genotyping test analyzes the specific variations or polymorphisms in the KIR genes to identify the presence or absence of different KIR gene alleles. These alleles can have different functional properties and can affect the individual’s immune response and susceptibility to certain diseases. The KIR genotyping test is typically performed using a blood or saliva sample. The DNA from the sample is isolated and specific regions of the KIR genes are amplified using polymerase chain reaction (PCR). The amplified DNA is then sequenced or analyzed using techniques such as Sanger sequencing or next-generation sequencing to determine the specific KIR gene alleles present in the individual. The results of the KIR genotyping test can provide valuable information about an individual’s immune system and can be used in various clinical and research settings. For example, it can help in assessing the compatibility between a donor and recipient for hematopoietic stem cell transplantation, as KIR genes are known to play a role in graft-versus-host disease and graft rejection. It can also be used to study the association between specific KIR gene alleles and the risk or progression of certain diseases, such as autoimmune disorders, infectious diseases, and cancer. Overall, KIR genotyping is a useful tool for understanding the genetic variations in the KIR genes and their implications in immune function and disease susceptibility. |